Before 1961, Ty Cobb scored the most runs, with 2,244 runs.

Interpreted as:

most runs by a player through 1960

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Ty Cobb T. Cobb	2,244	3,034	11,434	4,189	724	295	117	1,933	1,249	94	681	897		13,068	5,854	1,136	291				.366	.433	.512	.945	2534	1,093.6	.445	165	975.1
2	Babe Ruth B. Ruth	2,174	2,503	8,399	2,873	506	136	714	2,214	2,062	43	1,330	123		10,617	5,793	1,356	113				.342	.474	.690	1.164	2727	1,436.8	.513	197	1,369.6
3	Lou Gehrig L. Gehrig	1,888	2,164	8,001	2,721	534	163	493	1,995	1,508	45	790	102		9,660	5,060	1,190	106			2	.340	.447	.632	1.080	2265	1,046.8	.477	173	980
4	Tristram Speaker T. Speaker	1,882	2,789	10,195	3,514	792	222	117	1,531	1,381	103	394	436		11,988	5,101	1,131	309				.345	.428	.500	.928	2264	921	.436	157	812.3
5	Mel Ott M. Ott	1,859	2,730	9,456	2,876	488	72	511	1,860	1,708	64	896	89		11,337	5,041	1,071	109			38	.304	.414	.533	.947	2204	826.4	.430	156	794.2
6	Eddie Collins E. Collins	1,821	2,826	9,949	3,315	438	187	47	1,300	1,499	77	468	741		12,037	4,268	672	512				.333	.424	.429	.853	2032	693.4	.409	144	619.7
7	Stan Musial S. Musial	1,812	2,644	9,830	3,294	675	170	429	1,741	1,448	47	572	73	31	11,397	5,596	1,274	35	37	97	220	.335	.421	.569	.991	2272	980.1	.443	163	865.2
8	Ted Williams T. Williams	1,798	2,292	7,706	2,654	525	71	521	1,839	2,021	39	709	24	4	9,791	4,884	1,117	5	20	86	197	.344	.482	.634	1.116	2349	1,219.7	.493	188	1,067
9	Charlie Gehringer C. Gehringer	1,775	2,323	8,860	2,839	574	146	184	1,427	1,186	50	372	181		10,237	4,257	904	141			27	.320	.404	.480	.884	1797	516.6	.405	124	350
10	Jimmie Foxx J. Foxx	1,751	2,317	8,134	2,646	458	125	534	1,922	1,452	13	1,311	87		9,670	4,956	1,117	71			69	.325	.428	.609	1.038	2135	934.1	.460	158	780.8
11	Honus Wagner H. Wagner	1,739	2,794	10,439	3,420	643	252	101	1,732	963	125	735	723		11,748	4,870	996	221				.328	.391	.467	.858	2044	725.8	.408	147	650
12	Cap Anson C. Anson	1,722	2,277	9,104	3,012	529	124	97	1,306	953	32	146	247		10,123	4,080	750	34				.331	.396	.448	.844	2154	654.1	.397	134	525.3
13	Jesse Burkett J. Burkett	1,720	2,067	8,426	2,850	320	182	75	952	1,029	75	561	389		9,620	3,759	577	90				.338	.415	.446	.861	1921	592.9	.411	137	526.7
14	Willie Keeler W. Keeler	1,719	2,123	8,591	2,932	241	145	33	810	524	129	136	495		9,610	3,562	419	366				.341	.388	.415	.802	1640	406.6	.383	124	330.8
15	Billy Hamilton B. Hamilton	1,697	1,594	6,283	2,164	242	95	40	742	1,189	89	271	914		7,608	2,716	377	47				.344	.455	.432	.888	1716	578.6	.433	142	505.5
16	Bid McPhee B. McPhee	1,684	2,138	8,304	2,258	303	189	53	935	982	69	260	568		9,429	3,098	545	56				.272	.355	.373	.728	1594	183	.350	108	117.7
17	Jimmy Ryan J. Ryan	1,643	2,014	8,172	2,513	451	157	118	1,093	804	83	295	419		9,124	3,632	726	65				.308	.375	.444	.820	1709	379	.387	119	266.7
18	George Van Haltren G. Van Haltren	1,642	1,990	8,043	2,544	286	161	69	1,015	871	38	385	583		9,017	3,359	516	65				.316	.386	.418	.803	1647	328.4	.384	119	259.3
19	Paul Waner P. Waner	1,627	2,549	9,459	3,152	605	191	113	1,309	1,091	38	376	104		10,762	4,478	909	174			45	.333	.404	.473	.878	1868	537	.403	135	487.9
20	Fred Clarke F. Clarke	1,622	2,246	8,584	2,678	361	220	67	1,015	875	154	511	509		9,838	3,680	648	225				.312	.386	.429	.814	1663	445.8	.390	131	386.2
21	Roger Connor R. Connor	1,620	1,998	7,797	2,467	441	233	138	1,071	1,002	39	151	244		8,847	3,788	812	9				.316	.397	.486	.883	1952	630.3	.409	142	569.9
22	Jake Beckley J. Beckley	1,602	2,389	9,538	2,934	473	244	87	1,578	616	183	442	315		10,504	4,156	804	167				.308	.361	.436	.797	1803	356.2	.376	119	288.8
23	Ed Delahanty E. Delahanty	1,600	1,837	7,511	2,597	522	186	101	1,466	741	94	366	455		8,400	3,794	809	54				.346	.411	.505	.916	1836	616.8	.428	144	559.3
24	Bill Dahlen B. Dahlen	1,590	2,444	9,036	2,461	413	163	84	1,234	1,064	140	759	548		10,405	3,452	660	165				.272	.358	.382	.740	1589	236.5	.357	108	139.6
25	Rogers Hornsby R. Hornsby	1,579	2,259	8,173	2,930	541	169	301	1,584	1,038	48	679	135		9,475	4,712	1,011	216				.358	.434	.577	1.010	2018	899	.459	173	863.2