Since 2000, Mariano Rivera has the most saves, with 523 saves.

Interpreted as:

most regular-season saves by a player in by a pitcher since 2000

	NAME	SV	G	W	L	W%	GS	ERA	SO	CG	SHO	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Mariano Rivera M. Rivera	523	849	56	47	.544	0	2.05	836	0	0	907.0	698	207	227	49	167	38	768	28	3,562	8	8.30	1.66	5.01	0.49	23.5	4.7	0.95	.263	2.25	46	2.61	59	6.93	180.9
2	Kenley Jansen K. Jansen	452	881	49	37	.570	0	2.61	1,230	0	0	877.0	584	254	272	83	265	31	660	18	3,484	21	12.62	2.72	4.64	0.85	35.3	7.6	0.97	.267	2.79	66	2.57	63	5.99	143.3
3	Craig Kimbrel C. Kimbrel	440	837	56	47	.544	0	2.59	1,265	0	0	809.2	482	233	259	73	339	40	651	11	3,257	70	14.06	3.77	3.73	0.81	38.8	10.4	1.01	.266	2.88	63	2.58	63	5.36	131.9
4	Francisco Rodriguez F. Rodriguez	437	948	52	53	.495	0	2.86	1,142	0	0	976.0	738	310	336	98	389	17	677	42	4,011	68	10.53	3.59	2.94	0.90	28.5	9.7	1.15	.271	3.10	69	3.30	79	6.81	97
5	Joe Nathan J. Nathan	376	768	57	30	.655	15	2.72	922	0	0	833.0	606	252	272	67	298	22	585	31	3,376	45	9.96	3.22	3.09	0.72	27.3	8.8	1.09	.261	2.94	64	3.07	73	6.55	107.5
6	Trevor Hoffman T. Hoffman	373	596	25	47	.347	0	3.02	553	0	0	580.1	481	195	211	54	143	5	502	23	2,347	19	8.58	2.22	3.87	0.84	23.6	6.1	1.08	.268	3.27	75	3.15	75	7.46	71.8
7	Jonathan Papelbon J. Papelbon	368	689	41	36	.532	3	2.44	808	0	0	725.2	572	197	226	57	185	34	585	18	2,938	14	10.02	2.29	4.37	0.71	27.5	6.3	1.04	.278	2.80	58	2.80	69	7.09	105.2
8	Aroldis Chapman A. Chapman	339	809	57	45	.559	0	2.61	1,263	0	0	771.1	454	224	248	52	397	33	527	7	3,158	82	14.74	4.63	3.18	0.61	40.0	12.6	1.10	.285	2.89	64	2.41	58	5.30	147.3
9	Francisco Cordero F. Cordero	329	780	45	51	.469	0	3.38	777	0	0	805.2	732	303	335	62	357	27	571	28	3,460	36	8.68	3.99	2.18	0.69	22.5	10.3	1.35	.300	3.74	75	3.58	81	8.18	77.2
10	Fernando Rodney F. Rodney	327	951	48	71	.403	0	3.80	943	0	0	933.0	817	394	433	73	464	52	590	38	4,064	65	9.10	4.48	2.03	0.70	23.2	11.4	1.37	.294	4.18	91	3.76	90	7.88	43.6
11	Huston Street H. Street	324	668	42	34	.553	0	2.95	665	0	0	680.0	542	223	237	70	183	8	525	37	2,718	20	8.80	2.42	3.63	0.93	24.5	6.7	1.07	.263	3.14	71	3.32	81	7.17	61.7
12	Billy Wagner B. Wagner	321	629	30	26	.536	0	2.30	802	0	0	650.0	443	166	190	60	192	26	529	21	2,577	35	11.10	2.66	4.18	0.83	31.1	7.5	0.98	.256	2.63	53	2.81	64	6.13	111.4
13	Jason Isringhausen J. Isringhausen	291	644	33	33	.500	0	3.18	585	0	0	648.2	519	229	256	54	277	20	479	32	2,740	28	8.12	3.84	2.11	0.75	21.4	10.1	1.23	.258	3.55	76	3.72	87	7.20	40.3
14	Jose Valverde J. Valverde	288	626	27	33	.450	0	3.27	692	0	0	630.1	490	229	255	67	264	26	520	31	2,646	24	9.88	3.77	2.62	0.96	26.2	10.0	1.20	.265	3.64	76	3.65	85	7.00	45.6
15	Mark Melancon M. Melancon	262	732	37	40	.481	0	2.94	643	0	0	726.2	657	237	276	44	192	25	454	23	2,981	44	7.96	2.38	3.35	0.54	21.6	6.4	1.17	.295	3.42	73	3.03	76	8.14	75.9
16	Edwin Díaz E. Díaz	232	470	23	33	.411	0	3.04	761	0	0	465.0	327	157	169	52	168	34	355	9	1,898	30	14.73	3.25	4.53	1.01	40.1	8.9	1.06	.311	3.27	75	2.64	63	6.33	79.6
17	Armando Benitez A. Benitez	230	478	25	28	.472	0	3.12	535	0	0	487.1	356	169	188	64	233	5	378	19	2,026	11	9.88	4.30	2.30	1.18	26.4	11.5	1.21	.246	3.47	73	4.04	94	6.57	14.6
18	Raisel Iglesias R. Iglesias	229	541	39	51	.433	21	2.94	806	0	0	679.2	529	222	247	80	188	25	411	15	2,740	17	10.67	2.49	4.29	1.06	29.4	6.9	1.05	.274	3.27	69	3.26	77	7.00	72.4
19	Joakim Soria J. Soria	229	773	36	45	.444	1	3.11	831	0	0	763.0	633	264	279	67	231	27	427	18	3,146	33	9.80	2.72	3.60	0.79	26.4	7.3	1.13	.284	3.29	73	3.11	74	7.47	92.7
20	Brad Lidge B. Lidge	225	603	26	32	.448	1	3.54	799	0	0	603.1	492	237	257	57	287	34	368	41	2,589	46	11.92	4.28	2.78	0.85	30.9	11.1	1.29	.308	3.83	82	3.26	75	7.34	72.7
21	Greg Holland G. Holland	220	556	30	28	.517	0	3.14	677	0	0	547.2	417	191	211	43	241	7	355	20	2,271	50	11.13	3.96	2.81	0.71	29.8	10.6	1.20	.287	3.47	74	3.02	73	6.85	66.2
22	Troy Percival T. Percival	219	397	21	21	.500	1	3.37	370	0	0	385.0	281	144	157	51	168	14	322	13	1,599	17	8.65	3.93	2.20	1.19	23.1	10.5	1.17	.231	3.67	76	4.28	97	6.57	6.3
23	Rafael Soriano R. Soriano	207	591	24	28	.462	8	2.89	641	0	0	636.1	489	204	213	62	197	15	343	20	2,571	13	9.07	2.79	3.25	0.88	24.9	7.7	1.08	.258	3.01	71	3.34	81	6.92	58.6
24	Josh Hader J. Hader	206	433	29	29	.500	0	2.67	773	0	0	474.2	262	141	151	58	185	22	292	5	1,870	18	14.66	3.51	4.18	1.10	41.3	9.9	0.94	.245	2.86	65	2.81	67	4.97	74.1
25	Brian Fuentes B. Fuentes	204	650	26	43	.377	0	3.62	639	0	0	613.1	515	247	267	64	258	52	381	25	2,622	32	9.38	3.79	2.48	0.94	24.4	9.8	1.26	.280	3.92	81	3.86	88	7.56	37.4