Walter Johnson has the most career shutouts by a pitcher against a team, with 23 shutouts versus the Philadelphia Athletics.

Interpreted as:

most regular-season shutouts by a player against one team

	NAME	SHO	OPP	G	W	L	W%	GS	ERA	SO	CG	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Walter Johnson W. Johnson	23	Athletics	112	59	39	.602	93	1.81	516	74	4	826.0	715		277	22	185	26	17			20	5.62	2.02	2.79	0.24		5.5	1.09	.266	3.02	7.79
2	Walter Johnson W. Johnson	21	Yankees	108	61	38	.616	94	1.61	521	78	3	846.1	687		261	23	209	30	14			31	5.54	2.22	2.49	0.24		6.2	1.06	.256	2.78	7.31
3	Grover Alexander G. Alexander	20	Reds	108	70	24	.745	96	2.04	326	74	4	847.0	736		246	10	152	13	12			6	3.46	1.62	2.14	0.11		4.6	1.05	.257	2.61	7.82
4	Grover Alexander G. Alexander	16	Robins	95	56	23	.709	81	2.02	308	63	6	723.0	654		233	13	122	6	13			8	3.83	1.52	2.52	0.16		4.2	1.07	.260	2.90	8.14
5	Walter Johnson W. Johnson	15	Red Sox	112	53	43	.552	91	1.62	488	75	6	815.0	670		233	6	180	31	20			12	5.39	1.99	2.71	0.07		5.6	1.04	.262	2.57	7.40
6	Ed Walsh E. Walsh	15	Red Sox	65	35	14	.714	44	0.44	294	40	7	453.1	313		106	4	98	8	21			10	5.84	1.95	3.00	0.08		6.5	0.91	.278	2.10	6.21
7	Walter Johnson W. Johnson	14	White Sox	125	63	39	.618	99	1.47	540	81	10	898.1	662		259	13	197	26	25			25	5.41	1.97	2.74	0.13		5.6	0.96	.238	2.59	6.63
8	Eddie Plank E. Plank	14	Browns	68	43	18	.705	62	0.85	320	54	2	542.0	440		144	2	128	16	6			7	5.31	2.13	2.50	0.03		6.1	1.05	.267	2.39	7.31
9	Christy Mathewson C. Mathewson	14	Cubs	96	46	39	.541	87	0.89	355	75	5	749.1	654		283	18	113	4	8			17	4.26	1.36	3.14	0.22		3.8	1.02	.257	3.40	7.85
10	Christy Mathewson C. Mathewson	14	Braves	90	55	24	.696	78	1.19	410	63	3	687.0	598		209	9	133	7	9			16	5.37	1.74	3.08	0.12		4.9	1.06	.270	2.74	7.83
11	Whitey Ford W. Ford	13	White Sox	80	39	21	.650	73	2.17	284	32	0	526.1	450	127	157	29	157	9	2		2,143	12	4.86	2.68	1.81	0.50	13.3	7.3	1.15	.253	2.68	7.69
12	Grover Alexander G. Alexander	13	Cardinals	84	44	25	.638	70	2.36	331	55	5	617.0	576		212	19	117	9	12			6	4.83	1.71	2.83	0.28		4.7	1.12	.279	3.09	8.40
13	Walter Johnson W. Johnson	13	Browns	112	56	37	.602	91	1.61	481	73	3	801.2	658		253	12	179	33	18			20	5.40	2.01	2.69	0.13		5.6	1.04	.260	2.84	7.39
14	Vic Willis V. Willis	13	Superbas	59	31	24	.564	56	0.38	241	47	1	469.1	394		146	7	126	7	3			5	4.62	2.42	1.91	0.13		6.9	1.11	.266	2.80	7.56
15	Christy Mathewson C. Mathewson	13	Robins	77	49	19	.721	65	0.82	386	54	3	585.0	467		154	7	94	5	10			11	5.94	1.45	4.11	0.11		4.2	0.96	.260	2.37	7.18
16	Walter Johnson W. Johnson	12	Indians	109	59	41	.590	93	1.89	460	71	3	809.1	727		273	10	148	30	15			22	5.12	1.65	3.11	0.11		4.5	1.08	.275	3.04	8.08
17	Walter Johnson W. Johnson	12	Tigers	124	66	42	.611	105	1.88	521	79	5	920.0	798		346	11	276	32	19			25	5.10	2.70	1.89	0.11		7.5	1.17	.277	3.38	7.81
18	Doc White D. White	12	Tigers	71	33	22	.600	63	0.52	197	40	2	482.1	470		173	3	116	17	7			8	3.68	2.16	1.70	0.06		6.4	1.21	.313	3.23	8.77
19	Christy Mathewson C. Mathewson	12	Reds	95	65	19	.774	83	0.89	354	69	5	726.1	633		234	14	121	12	11			12	4.39	1.50	2.93	0.17		4.2	1.04	.263	2.90	7.84
20	Bob Gibson B. Gibson	11	Cubs	58	28	22	.560	53	2.95	338	33	1	440.0	367	144	154	27	161	6	2	24	1,823	13	6.91	3.29	2.10	0.55	18.5	8.8	1.20	.263	3.15	7.51
21	Warren Spahn W. Spahn	11	Phillies	92	47	30	.610	83	2.74	339	49	4	667.0	580	203	231	44	183	5	8		2,705	7	4.57	2.47	1.85	0.59	12.5	6.8	1.14	.251	3.12	7.83
22	Warren Spahn W. Spahn	11	Cardinals	125	64	41	.610	115	3.00	376	66	3	919.1	846	306	348	63	247	8	9		3,787	20	3.68	2.42	1.52	0.62	9.9	6.5	1.19	.253	3.41	8.28
23	Harry Brecheen H. Brecheen	11	Cubs	61	31	12	.721	47	2.03	202	35	2	420.1	337	95	102	22	99	6	5		1,656	3	4.33	2.12	2.04	0.47	12.2	6.0	1.04	.237	2.18	7.22
24	Grover Alexander G. Alexander	11	Braves	105	57	28	.671	83	2.06	318	66	7	755.2	692		246	22	115	8	18		3,039	5	3.79	1.37	2.77	0.26	10.5	3.8	1.07	.260	2.93	8.24
25	Chief Bender C. Bender	11	Browns	57	35	12	.745	46	0.82	270	39	2	396.2	319		112	3	84	14	9			7	6.13	1.91	3.21	0.07		5.7	1.02	.288	2.54	7.24