Randy Johnson has the most career starts when striking out 15+ batters, with 28 starts.

Interpreted as:

most regular-season starts by a pitcher with 15 or more k

	NAME	GS	SO	G	W	L	W%	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Randy Johnson R. Johnson	28	464	29	21	3	.875	1.36	16	7	0	244.1	138	37	39	11	57	7	1	0	928	4	17.09	2.10	8.14	0.41	50.0	6.1	0.80	.326	1.44	5.08
2	Nolan Ryan N. Ryan	26	423	26	20	2	.909	1.51	18	6	0	243.2	113	41	48	6	112	9	0	1	956	13	15.62	4.14	3.78	0.22	44.2	11.7	0.92	.264	1.77	4.17
3	Pedro Martinez P. Martinez	10	156	10	9	1	.900	0.53	5	2	0	85.0	37	5	6	3	11	2	0	0	301	1	16.52	1.16	14.18	0.32	51.8	3.7	0.56	.264	0.64	3.92
4	Roger Clemens R. Clemens	10	166	10	8	0	1.000	0.84	6	3	0	86.0	46	8	9	2	7	3	0	0	314	1	17.37	0.73	23.71	0.21	52.9	2.2	0.62	.324	0.94	4.81
5	Sandy Koufax S. Koufax	8	129	8	5	2	.714	1.96	5	0	0	82.2	51	18	21	9	33	1	0	5	331	3	14.04	3.59	3.91	0.98	39.0	10.0	1.02	.264	2.29	5.55
6	Rube Waddell R. Waddell	7	112	7	5	2	.714	0.32	7	0	0	83.1	49		17	1	26	3	0		325	4	12.10	2.81	4.31	0.11	34.5	8.0	0.90	.262	1.84	5.29
7	Max Scherzer M. Scherzer	6	98	6	5	0	1.000	1.12	3	2	0	48.1	19	6	6	4	5	2	0	1	171	0	18.25	0.93	19.60	0.74	57.3	2.9	0.50	.242	1.12	3.54
8	Sam McDowell S. McDowell	6	92	6	4	1	.800	1.32	3	0	0	54.2	29	8	11	1	19	1	1	2	208	2	15.15	3.13	4.84	0.16	44.2	9.1	0.88	.295	1.81	4.77
9	Tom Seaver T. Seaver	5	81	5	4	0	1.000	0.94	4	1	0	48.0	14	5	5	3	10	0	0	1	168	0	15.19	1.88	8.10	0.56	48.2	6.0	0.50	.149	0.94	2.63
10	Steve Carlton S. Carlton	5	82	5	1	3	.250	3.64	4	0	0	42.0	44	17	17	5	13	0	0	0	177	2	17.57	2.79	6.31	1.07	46.3	7.3	1.36	.506	3.64	9.43
11	Dazzy Vance D. Vance	5	77	5	4	0	1.000	2.87	4	1	0	47.0	37	15	15	0	18	0	0		190	0	14.74	3.45	4.28	0.00	40.5	9.5	1.17	.389	2.87	7.09
12	Chris Sale C. Sale	4	62	4	2	0	1.000	1.78	0	0	0	30.1	13	6	6	2	4	1	0	0	110	0	18.40	1.19	15.50	0.59	56.4	3.6	0.56	.268	1.78	3.86
13	Curt Schilling C. Schilling	4	63	4	3	1	.750	1.32	2	1	0	34.0	19	5	5	3	4	0	0	0	123	0	16.68	1.06	15.75	0.79	51.2	3.3	0.68	.302	1.32	5.03
14	Dwight Gooden D. Gooden	4	63	4	3	1	.750	1.09	3	2	0	33.0	28	4	5	0	4	1	0	0	130	1	17.18	1.09	15.75	0.00	48.5	3.1	0.97	.452	1.36	7.64
15	Bob Feller B. Feller	4	66	4	3	1	.750	1.75	4	0	0	36.0	19	7	8	0	24	2	0		150	2	16.50	6.00	2.75	0.00	44.0	16.0	1.19	.328	2.00	4.75
16	Gerrit Cole G. Cole	3	46	3	3	0	1.000	0.75	1	1	0	24.0	6	2	2	1	1	0	0	0	79	0	17.25	0.38	46.00	0.38	58.2	1.3	0.29	.161	0.75	2.25
17	Frank Tanana F. Tanana	3	47	3	2	0	1.000	1.93	2	0	0	28.0	25	6	6	3	6	1	0	0	113	1	15.11	1.93	7.83	0.96	41.6	5.3	1.11	.393	1.93	8.04
18	J.R. Richard	3	45	3	2	0	1.000	1.55	2	0	0	29.0	20	5	6	1	7	0	0	1	116	1	13.97	2.17	6.43	0.31	38.8	6.0	0.93	.302	1.86	6.21
19	Mickey Lolich M. Lolich	3	47	3	2	0	1.000	1.67	2	0	0	27.0	14	5	5	2	8	3	0	0	104	0	15.67	2.67	5.88	0.67	45.2	7.7	0.81	.273	1.67	4.67
20	Bob Gibson B. Gibson	3	46	3	2	1	.667	1.67	3	0	0	27.0	15	5	8	1	5	0	0	0	102	0	15.33	1.67	9.20	0.33	45.1	4.9	0.74	.280	2.67	5.00
21	Luis Tiant L. Tiant	3	51	3	3	0	1.000	0.96	3	1	0	28.0	18	3	3	2	6	0	0	0	106	0	16.39	1.93	8.50	0.64	48.1	5.7	0.86	.340	0.96	5.79
22	Don Wilson D. Wilson	3	49	3	3	0	1.000	1.00	3	1	0	27.0	11	3	3	1	7	0	0	1	98	2	16.33	2.33	7.00	0.33	50.0	7.1	0.67	.244	1.00	3.67
23	Bob Veale B. Veale	3	47	3	1	1	.500	0.59	2	1	0	30.1	19	2	2	0	12	0	0	4	121	0	13.95	3.56	3.92	0.00	38.8	9.9	1.02	.306	0.59	5.64
24	Walker Buehler W. Buehler	2	31	2	2	0	1.000	1.50	2	0	0	18.0	8	3	3	3	0	0	0	0	61	1	15.50	0.00		1.50	50.8	0.0	0.44	.185	1.50	4.00
25	Clayton Kershaw C. Kershaw	2	30	2	2	0	1.000	0.50	2	1	0	18.0	6	1	1	0	1	0	0	0	60	0	15.00	0.50	30.00	0.00	50.0	1.7	0.39	.207	0.50	3.00