Julio Franco has the most career strikeouts by a player older than 40, with 336 strikeouts.

Interpreted as:

most strikeouts by a player after age 40

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Julio Franco J. Franco	336	637	1,434	181	409	72	7	32	213	164	5	21	6	1,619	591	111	4	12	17	57	.285	.358	.412	.770
2	Carlton Fisk C. Fisk	268	461	1,528	168	403	75	3	53	232	154	19	12	5	1,713	643	131	1	11	25	48	.264	.336	.421	.757
3	Nelson Cruz N. Cruz	238	244	863	101	202	31	1	29	129	80	9	7	0	961	322	61	0	9	9	23	.234	.303	.373	.676
4	Rickey Henderson R. Henderson	222	348	1,050	192	239	38	6	19	95	218	12	72	20	1,290	346	63	3	7	1	22	.228	.364	.330	.694
5	Dave Winfield D. Winfield	184	267	959	118	244	47	5	33	124	91	1	5	4	1,056	400	85	1	4	10	27	.254	.318	.417	.736
6	Raul Ibanez R. Ibanez	157	179	575	60	121	23	4	25	67	68	0	3	2	644	227	52	0	1	1	8	.210	.293	.395	.688
7	Pete Rose P. Rose	151	620	2,123	249	555	74	13	5	204	274	20	27	17	2,446	670	92	13	16	23	45	.261	.349	.316	.665
8	Ichiro Suzuki I. Suzuki	136	449	970	117	245	26	11	5	63	82	4	22	8	1,071	308	42	9	6	3	14	.253	.312	.318	.629
9	Omar Vizquel O. Vizquel	136	380	1,107	108	279	40	6	3	82	87	2	24	15	1,231	340	49	24	11	9	19	.252	.305	.307	.612
10	Andres Galarraga A. Galarraga	132	191	523	61	147	24	0	21	76	42	8	2	5	575	234	45	0	2	6	17	.281	.343	.447	.790
11	Graig Nettles G. Nettles	120	355	743	68	162	30	1	24	121	84	2	1	1	837	266	55	0	8	14	19	.218	.296	.358	.654
12	Darrell Evans D. Evans	116	213	596	71	125	13	1	31	90	110	1	0	3	713	233	45	0	6	10	10	.210	.331	.391	.722
13	Jack Quinn J. Quinn	114	322	418	18	64	10	0	1	43	19	1	0		469	77	11	31				.153	.192	.184	.376
14	Craig Biggio C. Biggio	112	141	517	68	130	31	3	10	50	23	3	4	3	555	197	44	7	5	0	5	.251	.285	.381	.666
15	Tony Perez T. Perez	112	284	675	61	174	32	3	14	97	79	1	0	2	762	254	49	0	7	6	21	.258	.333	.376	.710
16	Barry Bonds B. Bonds	111	270	749	157	205	38	0	59	153	256	13	8	0	1,022	420	97	0	4	84	22	.274	.464	.561	1.025
17	Carl Yastrzemski C. Yastrzemski	110	351	1,208	133	318	60	2	36	187	166	4	0	3	1,385	490	98	0	7	16	35	.263	.352	.406	.758
18	Edgar Martinez E. Martinez	107	141	486	45	128	23	0	12	63	58	2	1	0	549	187	35	0	3	10	15	.263	.342	.385	.727
19	Bartolo Colon B. Colon	101	97	189	10	15	4	0	1	6	1	1	0	0	207	22	5	15	1	0	6	.079	.089	.116	.205
20	Albert Pujols A. Pujols	100	218	582	71	148	17	0	41	118	42	15	3	2	647	288	58	0	8	4	27	.254	.317	.495	.812
21	Jamie Moyer J. Moyer	96	130	229	13	25	3	0	0	11	20	1	0	0	293	28	3	42	1	0	2	.109	.183	.122	.306
22	Willie McCovey W. McCovey	93	165	466	42	111	17	0	16	73	49	2	0	2	523	176	33	0	6	4	10	.238	.310	.378	.687
23	Jason Giambi J. Giambi	92	157	335	31	62	14	0	12	44	52	7	0	1	399	112	26	0	5	4	15	.185	.303	.334	.638
24	Stan Musial S. Musial	91	259	770	91	229	28	3	31	140	99	5	5	0	884	356	62	0	10	13	16	.297	.377	.462	.839
25	Willie Mays W. Mays	90	137	405	51	97	19	1	14	44	71	2	2	5	483	160	34	4	1	6	12	.240	.355	.395	.750

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StatMuse has game-level data for strikeouts going back to the 1916 season.

Some of the information used here was obtained free of charge from Retrosheet.

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TEAM	W	L	PCT	GB
Braves	83	57	.593
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Nationals	67	75	.472	17.0
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DATE	MATCHUP			TIME (ET)
Fri 9/4	ATL	@	PHI	6:40 PM
Sat 9/5	ATL	@	PHI	6:05 PM
Sun 9/6	ATL	@	PHI	1:10 PM
Mon 9/7	ATL	@	PHI	1:05 PM
Tue 9/8	TBR	@	ATL	7:15 PM

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Braves	83	57	.593
Phillies	79	61	.564	4.0
Marlins	71	69	.507	12.0
Nationals	67	75	.472	17.0
Mets	63	77	.450	20.0
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Brewers	87	53	.621
Cubs	78	62	.557	9.0
Cardinals	70	70	.500	17.0
Pirates	68	72	.486	19.0
Reds	67	73	.479	20.0
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Red Sox	75	65	.536	8.5
Blue Jays	69	71	.493	14.5
Orioles	69	71	.493	14.5
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White Sox	73	66	.525
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Twins	67	73	.479	6.5
Tigers	64	75	.460	9.0
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Astros	71	69	.507
Rangers	69	71	.493	2.0
Mariners	66	74	.471	5.0
Athletics	54	86	.386	17.0
Angels	53	87	.379	18.0