Rick Reichardt has the most strikeouts by a rookie in a game, with 6 strikeouts against the Cleveland Indians on May 31, 1966.

Interpreted as:

most strikeouts by a rookie in 1 regular-season game

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Rick Reichardt R. Reichardt	6	5/31/1966	CAL	vs	CLE	8	0	0	0	0	0	0	0	0	0	0	8	0	0	0	0	0	0
2	Dylan Crews D. Crews	5	3/29/2025	WSH	vs	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
3	Connor Norby C. Norby	5	9/26/2024	MIA	@	MIN	6	0	0	0	0	0	0	1	0	0	0	7	0	0	0	0	0	0
4	Bryson Stott B. Stott	5	4/16/2022	PHI	@	MIA	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
5	Daniel Johnson D. Johnson	5	5/2/2021	CLE	@	CWS	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
6	Brandon Lowe B. Lowe	5	5/8/2019	TBR	vs	ARI	6	0	1	0	0	0	0	0	0	0	0	6	1	0	0	0	0	0
7	Dustin Fowler D. Fowler	5	7/9/2018	OAK	@	HOU	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
8	Chad Wallach C. Wallach	5	3/30/2018	MIA	vs	CHC	7	0	0	0	0	0	0	0	0	0	0	7	0	0	0	0	0	0
9	Matt Davidson M. Davidson	5	5/30/2017	CWS	vs	BOS	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
10	Roman Quinn R. Quinn	5	9/24/2016	PHI	@	NYM	6	1	1	0	0	0	0	0	0	0	0	6	1	0	0	0	0	0
11	Max Kepler M. Kepler	5	9/4/2016	MIN	vs	CWS	7	2	1	0	0	0	0	0	0	0	0	7	1	0	0	0	0	0
12	Tim Anderson T. Anderson	5	8/10/2016	CWS	@	KCR	6	0	1	0	0	0	1	1	0	0	0	7	1	0	0	0	0	0
13	Randal Grichuk R. Grichuk	5	5/18/2015	STL	@	NYM	6	0	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
14	David Adams D. Adams	5	9/29/2013	NYY	@	HOU	6	0	1	0	1	0	0	0	0	0	0	6	3	1	0	0	0	0
15	Bryce Harper B. Harper	5	6/16/2012	WSH	vs	NYY	7	0	0	0	0	0	0	0	0	0	0	7	0	0	0	0	0	0
16	Justin Smoak J. Smoak	5	6/13/2010	TEX	@	MIL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
17	Jason Heyward J. Heyward	5	6/4/2010	ATL	@	LAD	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
18	Geovany Soto G. Soto	5	4/26/2008	CHC	@	WSH	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
19	Clay Hensley C. Hensley	5	5/14/2006	SDP	@	CHC	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
20	Andy Phillips A. Phillips	5	5/2/2005	NYY	@	TBD	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
21	Mark Teixeira M. Teixeira	5	8/18/2003	TEX	@	DET	7	0	1	0	0	0	0	0	0	0	0	7	1	0	0	0	0	0
22	Ryan Thompson R. Thompson	5	9/29/1993	NYM	vs	STL	7	0	0	0	0	0	0	0	0	0	0	7	0	0	0	0	0	0
23	Roberto Mejia R. Mejia	5	8/9/1993	COL	@	LAD	6	1	1	0	0	0	0	0	0	0	0	6	1	0	0	0	0	0
24	Phil Plantier P. Plantier	5	10/1/1991	BOS	vs	DET	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
25	Dean Palmer D. Palmer	5	9/23/1991	TEX	@	SEA	6	1	1	1	0	0	2	0	0	0	0	6	2	1	0	0	0	0

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Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.

Some of the information used here was obtained free of charge from Retrosheet.

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Rick Reichardt has the most strikeouts by a rookie in a game, with 6 strikeouts against the Cleveland Indians on May 31, 1966.

Interpreted as:

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