Since 2006, Justin Verlander has struck out the most batters, with 3,546 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Justin Verlander J. Verlander	3,546	553	266	156	.630	553	3.31	26	9	0	3556.1	3,031	1,308	1,419	370	999	120	0	28	14,553	98	8.97	2.53	3.55	0.94	24.4	6.9	1.13	.280	3.59	78	3.43	81	7.67	311.1
2	Max Scherzer M. Scherzer	3,489	483	220	117	.653	474	3.22	12	5	0	2963.0	2,433	1,059	1,132	354	779	114	2	20	11,987	80	10.60	2.37	4.48	1.08	29.1	6.5	1.08	.287	3.44	77	3.23	78	7.39	302.5
3	Clayton Kershaw C. Kershaw	3,052	455	223	96	.699	451	2.53	25	15	0	2855.1	2,193	804	881	235	713	46	1	28	11,279	108	9.62	2.25	4.28	0.74	27.1	6.3	1.02	.271	2.78	65	2.85	70	6.91	375.1
4	Zack Greinke Z. Greinke	2,765	529	212	128	.624	484	3.33	15	5	1	3061.1	2,831	1,133	1,221	318	683	58	8	22	12,449	96	8.13	2.01	4.05	0.93	22.2	5.5	1.15	.291	3.59	80	3.40	83	8.32	239.5
5	Chris Sale C. Sale	2,579	393	145	88	.622	312	3.01	16	3	12	2084.0	1,692	697	750	213	487	130	25	15	8,389	48	11.14	2.10	5.30	0.92	30.7	5.8	1.05	.297	3.24	70	2.87	68	7.31	303.3
6	Cole Hamels C. Hamels	2,560	423	163	122	.572	422	3.43	17	7	0	2698.0	2,424	1,027	1,103	310	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
7	Jon Lester J. Lester	2,488	452	200	117	.631	451	3.66	15	4	0	2740.0	2,610	1,114	1,215	294	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
8	Felix Hernandez F. Hernandez	2,447	407	165	132	.556	406	3.44	25	11	0	2645.1	2,426	1,012	1,131	259	782	103	0	16	10,956	153	8.33	2.66	3.13	0.88	22.3	7.1	1.21	.294	3.85	85	3.54	86	8.25	168
9	CC Sabathia	2,332	404	182	116	.611	403	3.60	32	10	0	2604.2	2,506	1,042	1,154	288	716	95	0	34	10,893	49	8.06	2.47	3.26	1.00	21.4	6.6	1.24	.297	3.99	84	3.70	85	8.66	183.5
10	Gerrit Cole G. Cole	2,251	317	153	80	.657	317	3.18	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
11	James Shields J. Shields	2,234	407	145	139	.511	405	4.01	23	9	0	2616.0	2,581	1,167	1,267	361	746	97	1	22	10,993	107	7.69	2.57	2.99	1.24	20.3	6.8	1.27	.294	4.36	98	4.16	101	8.88	-13.5
12	Adam Wainwright A. Wainwright	2,202	476	200	128	.610	411	3.52	28	11	3	2666.1	2,575	1,044	1,114	232	735	81	12	40	11,107	51	7.43	2.48	3.00	0.78	19.8	6.6	1.24	.298	3.76	88	3.53	87	8.69	154.3
13	Charlie Morton C. Morton	2,196	416	147	134	.523	409	4.13	3	2	0	2267.2	2,143	1,040	1,139	226	859	200	1	27	9,755	72	8.72	3.41	2.56	0.90	22.5	8.8	1.32	.306	4.52	103	3.89	97	8.51	36.6
14	David Price D. Price	2,076	400	157	82	.657	322	3.32	17	3	3	2143.2	1,930	790	865	221	562	63	19	16	8,807	40	8.72	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
15	Yu Darvish Y. Darvish	2,075	297	115	93	.553	297	3.65	2	1	0	1778.0	1,460	721	756	231	563	83	0	8	7,305	83	10.50	2.85	3.69	1.17	28.4	7.7	1.14	.282	3.83	87	3.58	85	7.39	120
16	Madison Bumgarner M. Bumgarner	2,070	358	134	124	.519	355	3.47	16	7	0	2209.1	2,007	853	933	258	544	89	1	38	9,098	29	8.43	2.22	3.81	1.05	22.8	6.0	1.15	.285	3.80	90	3.62	94	8.18	50.1
17	Lance Lynn L. Lynn	2,015	364	143	99	.591	340	3.74	4	2	1	2006.1	1,856	834	916	231	704	89	4	21	8,520	61	9.04	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
18	Kevin Gausman K. Gausman	1,954	361	112	113	.498	322	3.81	4	2	0	1911.0	1,835	810	866	233	535	38	11	11	7,986	64	9.20	2.52	3.65	1.10	24.5	6.7	1.24	.307	4.08	92	3.59	85	8.64	132.7
19	Sonny Gray S. Gray	1,925	339	125	102	.551	330	3.58	7	5	0	1918.0	1,675	763	836	192	621	57	2	5	7,952	106	9.03	2.91	3.10	0.90	24.2	7.8	1.20	.288	3.92	87	3.51	85	7.86	136.2
20	Ervin Santana E. Santana	1,879	402	139	121	.535	363	4.08	20	10	0	2353.0	2,252	1,066	1,148	314	729	96	20	33	9,899	100	7.19	2.79	2.58	1.20	19.0	7.4	1.27	.282	4.39	98	4.30	104	8.61	-41.2
21	Aaron Nola A. Nola	1,876	285	109	89	.551	285	3.83	6	4	0	1715.2	1,522	730	769	217	449	56	0	16	7,039	18	9.84	2.36	4.18	1.14	26.7	6.4	1.15	.294	4.03	91	3.50	82	7.98	147.1
22	Patrick Corbin P. Corbin	1,860	373	110	142	.437	354	4.51	7	2	2	2047.2	2,179	1,025	1,102	284	630	51	10	24	8,809	67	8.18	2.77	2.95	1.25	21.1	7.2	1.37	.317	4.84	107	4.13	99	9.58	9.7
23	Gio Gonzalez G. Gonzalez	1,860	344	131	101	.565	328	3.70	4	2	0	1933.0	1,744	795	857	171	815	50	4	21	8,242	59	8.66	3.79	2.28	0.80	22.6	9.9	1.32	.294	3.99	91	3.67	91	8.12	77.3
24	Johnny Cueto J. Cueto	1,857	370	144	113	.560	365	3.52	18	8	0	2256.1	2,094	883	955	253	637	120	1	22	9,373	36	7.41	2.54	2.92	1.01	19.8	6.8	1.21	.283	3.81	86	3.93	96	8.35	31.8
25	Jacob deGrom J. deGrom	1,851	248	96	65	.596	248	2.57	4	2	0	1539.2	1,173	440	477	146	345	25	0	13	6,045	30	10.82	2.02	5.37	0.85	30.6	5.7	0.99	.279	2.79	66	2.70	66	6.86	239.4