Between the 1973 and 2015 seasons, Jim Thome had the most strikeouts, with 2,548 strikeouts.

Interpreted as:

most strikeouts by a player from 1973 to 2015

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Jim Thome J. Thome	2,548	2,543	8,422	1,583	2,328	451	26	612	1,699	1,747	69	19	20	10,313	4,667	1,089	1	74	173	165	.276	.402	.554	.956	1925	653.9	.406	145	589.5
2	Adam Dunn A. Dunn	2,379	2,001	6,883	1,097	1,631	334	10	462	1,168	1,317	86	63	25	8,328	3,371	806	2	40	122	100	.237	.364	.490	.854	1285	297.9	.367	123	240
3	Sammy Sosa S. Sosa	2,306	2,354	8,813	1,475	2,408	379	45	609	1,667	929	59	234	107	9,896	4,704	1,033	17	78	154	202	.273	.344	.534	.878	1559	345.1	.370	124	307.3
4	Alex Rodriguez A. Rodriguez	2,220	2,719	10,341	2,002	3,070	541	31	687	2,055	1,324	175	326	76	11,964	5,734	1,259	16	108	97	257	.297	.382	.554	.937	2161	702.2	.398	142	642.4
5	Andres Galarraga A. Galarraga	2,003	2,257	8,096	1,195	2,333	444	32	399	1,425	583	178	128	81	8,916	4,038	875	1	58	106	179	.288	.347	.499	.846	1355	286.5	.365	118	193.8
6	Jose Canseco J. Canseco	1,942	1,887	7,057	1,186	1,877	340	14	462	1,407	906	84	200	88	8,129	3,631	816	1	81	63	178	.266	.353	.515	.867	1293	321.2	.375	130	300.8
7	Mike Cameron M. Cameron	1,901	1,955	6,839	1,064	1,700	383	59	278	968	867	87	297	83	7,884	3,035	720	31	60	19	114	.249	.338	.444	.782	1043	70.3	.341	107	69.2
8	Fred McGriff F. McGriff	1,882	2,460	8,757	1,349	2,490	441	24	493	1,550	1,305	39	72	38	10,174	4,458	958	2	71	171	226	.284	.377	.509	.886	1678	454.1	.383	134	415.9
9	Mike Schmidt M. Schmidt	1,868	2,391	8,318	1,504	2,227	408	59	547	1,592	1,502	78	174	92	10,022	4,394	1,014	16	108	201	156	.268	.380	.528	.909	1713	591.1	.396	147	540.6
10	Bobby Abreu B. Abreu	1,840	2,425	8,480	1,453	2,470	574	59	288	1,363	1,476	33	400	128	10,081	4,026	921	7	85	115	165	.291	.395	.475	.870	1648	417.8	.378	129	382
11	Derek Jeter D. Jeter	1,840	2,747	11,195	1,923	3,465	544	66	260	1,311	1,082	170	358	97	12,602	4,921	870	97	58	39	287	.310	.377	.440	.817	1877	346.6	.360	119	305.9
12	Reggie Jackson R. Jackson	1,817	2,045	7,152	1,117	1,884	335	29	406	1,283	1,004	52	149	70	8,262	3,495	770	1	53	116	149	.263	.356	.489	.845	1262	338	.373	136	338.1
13	Manny Ramirez M. Ramirez	1,813	2,302	8,244	1,544	2,574	547	20	555	1,831	1,329	109	38	33	9,774	4,826	1,122	2	90	216	243	.312	.411	.585	.996	1931	719.5	.418	153	658.7
14	Alfonso Soriano A. Soriano	1,803	1,975	7,750	1,152	2,095	481	31	412	1,159	496	86	289	84	8,395	3,874	924	9	54	68	123	.270	.319	.500	.819	1163	161.7	.348	111	112.7
15	Ken Griffey Jr. K. Griffey Jr.	1,779	2,671	9,801	1,662	2,781	524	38	630	1,836	1,312	81	184	69	11,304	5,271	1,192	8	102	246	199	.284	.370	.538	.907	1892	521.1	.384	132	453.4
16	Craig Biggio C. Biggio	1,753	2,850	10,876	1,844	3,060	668	55	291	1,175	1,160	285	414	124	12,503	4,711	1,014	101	81	68	150	.281	.363	.433	.796	1768	248.9	.352	115	238.9
17	Andruw Jones A. Jones	1,748	2,196	7,599	1,204	1,933	383	36	434	1,289	891	97	152	59	8,664	3,690	853	6	71	69	192	.254	.337	.486	.823	1229	161.4	.352	111	122.2
18	Dale Murphy D. Murphy	1,748	2,180	7,960	1,197	2,111	350	39	398	1,266	986	28	161	68	9,040	3,733	787	6	60	159	209	.265	.346	.469	.815	1291	273.7	.357	119	202.4
19	Carlos Delgado C. Delgado	1,745	2,035	7,283	1,241	2,038	483	18	473	1,512	1,109	172	14	8	8,657	3,976	974	0	93	186	152	.280	.383	.546	.929	1513	435.7	.391	135	394
20	Torii Hunter T. Hunter	1,741	2,372	8,857	1,296	2,452	498	39	353	1,391	661	97	195	99	9,692	4,087	890	6	71	52	262	.277	.331	.461	.793	1291	137.2	.342	110	111.7
21	Ryan Howard R. Howard	1,729	1,460	5,376	813	1,410	267	21	357	1,135	682	58	12	4	6,168	2,790	645	0	52	152	109	.262	.349	.519	.868	940	218.3	.364	124	183
22	Jim Edmonds J. Edmonds	1,729	2,011	6,858	1,251	1,949	437	25	393	1,199	998	49	67	50	7,980	3,615	855	10	65	91	122	.284	.376	.527	.903	1352	362.4	.385	132	326.3
23	Chili Davis C. Davis	1,698	2,435	8,673	1,240	2,380	424	30	350	1,372	1,194	15	142	98	9,996	3,914	804	20	94	188	232	.274	.360	.451	.811	1420	249.9	.354	118	225.1
24	Rickey Henderson R. Henderson	1,694	3,081	10,961	2,295	3,055	510	66	297	1,115	2,190	98	1,406	335	13,346	4,588	873	30	67	61	172	.279	.401	.419	.820	2074	509.6	.372	132	507.9
25	Dave Winfield D. Winfield	1,686	2,973	11,003	1,669	3,110	540	88	465	1,833	1,216	25	223	96	12,358	5,221	1,093	19	95	172	319	.283	.353	.475	.827	1811	416.2	.364	128	400.6