4 players are tied for the most strikeouts for the Pirates in a game, with 5 strikeouts. The first three are Starling Marte on April 18, 2013, Bert Blyleven on July 27, 1979 and Ron Kline on September 22, 1958.

Interpreted as:

most strikeouts in a regular-season game for a pirate

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Starling Marte S. Marte	5	4/18/2013	PIT	vs	ATL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
2	Bert Blyleven B. Blyleven	5	7/27/1979	PIT	@	MON	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
3	Ron Kline R. Kline	5	9/22/1958	PIT	@	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
4	Pep Young P. Young	5	9/29/1935	PIT	@	CIN	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0			0
5	Joey Bart J. Bart	4	6/23/2025	PIT	@	MIL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
6	Oneil Cruz O. Cruz	4	6/19/2025	PIT	@	DET	6	0	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
7	Andrew McCutchen A. McCutchen	4	6/5/2025	PIT	vs	HOU	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
8	Ke'Bryan Hayes K. Hayes	4	5/30/2025	PIT	@	SDP	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
9	Oneil Cruz O. Cruz	4	5/18/2025	PIT	@	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
10	Jack Suwinski J. Suwinski	4	4/18/2025	PIT	vs	CLE	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
11	Yasmani Grandal Y. Grandal	4	8/9/2024	PIT	@	LAD	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
12	Oneil Cruz O. Cruz	4	7/30/2024	PIT	@	HOU	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
13	Jack Suwinski J. Suwinski	4	5/16/2024	PIT	@	CHC	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
14	Michael A. Taylor M. A. Taylor	4	4/14/2024	PIT	@	PHI	4	0	0	0	0	0	0	1	0	0	0	5	0	0	0	0	0	0
15	Oneil Cruz O. Cruz	4	4/14/2024	PIT	@	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
16	Andrew McCutchen A. McCutchen	4	3/28/2024	PIT	@	MIA	5	0	0	0	0	0	1	1	0	0	0	6	0	0	0	0	0	0
17	Ke'Bryan Hayes K. Hayes	4	9/26/2023	PIT	@	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
18	Liover Peguero L. Peguero	4	9/22/2023	PIT	@	CIN	4	0	0	0	0	0	0	1	0	0	0	5	0	0	0	0	0	0
19	Jack Suwinski J. Suwinski	4	6/22/2023	PIT	@	MIA	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
20	Ke'Bryan Hayes K. Hayes	4	5/28/2023	PIT	@	SEA	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
21	Jack Suwinski J. Suwinski	4	4/7/2023	PIT	vs	CWS	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
22	Canaan Smith-Njigba C. Smith-Njigba	4	4/4/2023	PIT	@	BOS	4	1	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
23	Jack Suwinski J. Suwinski	4	9/18/2022	PIT	@	NYM	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
24	Oneil Cruz O. Cruz	4	9/17/2022	PIT	@	NYM	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
25	Oneil Cruz O. Cruz	4	9/14/2022	PIT	@	CIN	5	1	1	0	0	1	2	0	0	0	0	5	4	1	0	0	0	0