Nolan Ryan has the most career strikeouts - hits allowed, with 1,791.

	NAME	SO-H	SO	H	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Nolan Ryan N. Ryan	1,791	5,714	3,923	807	324	292	.526	773	3.19	222	61	3	5386.0	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56	370.2
2	Randy Johnson R. Johnson	1,529	4,875	3,346	618	303	166	.646	603	3.29	100	37	2	4135.1	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
3	Max Scherzer M. Scherzer	1,056	3,489	2,433	483	220	117	.653	474	3.22	12	5	0	2963.0	1,059	1,132	354	779	114	2	20	11,987	80	10.60	2.37	4.48	1.08	29.1	6.5	1.08	.287	3.44	77	3.23	78	7.39	302.5
4	Pedro Martinez P. Martinez	933	3,154	2,221	476	219	100	.687	409	2.93	46	17	3	2827.1	919	1,006	239	760	141	23	30	11,394	62	10.04	2.42	4.15	0.76	27.7	6.7	1.05	.279	3.20	66	2.91	68	7.07	454.6
5	Chris Sale C. Sale	887	2,579	1,692	393	145	88	.622	312	3.01	16	3	12	2084.0	697	750	213	487	130	25	15	8,389	48	11.14	2.10	5.30	0.92	30.7	5.8	1.05	.297	3.24	70	2.87	68	7.31	303.3
6	Clayton Kershaw C. Kershaw	859	3,052	2,193	455	223	96	.699	451	2.53	25	15	0	2855.1	804	881	235	713	46	1	28	11,279	108	9.62	2.25	4.28	0.74	27.1	6.3	1.02	.271	2.78	65	2.85	70	6.91	375.1
7	Aroldis Chapman A. Chapman	856	1,331	475	863	60	47	.561	0	2.52	0	0	367	821.1	230	255	54	408	33	563	7	3,341	87	14.58	4.47	3.26	0.59	39.8	12.2	1.08	.278	2.79	61	2.36	57	5.20	161.8
8	Craig Kimbrel C. Kimbrel	790	1,282	492	851	56	48	.538	0	2.58	0	0	440	821.2	236	263	75	346	40	656	11	3,306	70	14.04	3.79	3.71	0.82	38.8	10.5	1.02	.267	2.88	63	2.60	64	5.39	131.8
9	Jacob deGrom J. deGrom	678	1,851	1,173	248	96	65	.596	248	2.57	4	2	0	1539.2	440	477	146	345	25	0	13	6,045	30	10.82	2.02	5.37	0.85	30.6	5.7	0.99	.279	2.79	66	2.70	66	6.86	239.4
10	Kenley Jansen K. Jansen	668	1,278	610	934	54	40	.574	0	2.57	0	0	475	927.1	265	284	88	282	32	700	20	3,680	21	12.40	2.74	4.53	0.85	34.7	7.7	0.96	.261	2.76	65	2.62	64	5.92	147.2
11	Sandy Koufax S. Koufax	642	2,396	1,754	397	165	87	.655	314	2.76	137	40	9	2324.1	713	806	204	817	18	44	48	9,497	87	9.28	3.16	2.93	0.79	25.2	8.6	1.11	.256	3.12	75	2.69	75	6.79	226.6
12	Gerrit Cole G. Cole	624	2,251	1,627	317	153	80	.657	317	3.18	8	5	0	1954.0	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
13	Yu Darvish Y. Darvish	615	2,075	1,460	297	115	93	.553	297	3.65	2	1	0	1778.0	721	756	231	563	83	0	8	7,305	83	10.50	2.85	3.69	1.17	28.4	7.7	1.14	.282	3.83	87	3.58	85	7.39	120
14	Billy Wagner B. Wagner	595	1,196	601	853	47	40	.540	0	2.31	0	0	422	903.0	232	262	82	300	33	703	26	3,600	43	11.92	2.99	3.99	0.82	33.2	8.3	1.00	.261	2.61	54	2.72	63	5.99	159
15	Blake Snell B. Snell	549	1,440	891	222	81	62	.566	222	3.15	1	1	0	1158.0	405	440	111	521	11	0	6	4,791	86	11.19	4.05	2.76	0.86	30.1	10.9	1.22	.288	3.42	77	3.31	79	6.92	111.7
16	Josh Hader J. Hader	547	829	282	468	34	31	.523	0	2.64	0	0	226	512.1	150	164	65	198	24	321	6	2,019	19	14.56	3.48	4.19	1.14	41.1	9.8	0.94	.240	2.88	64	2.88	69	4.95	75.7
17	Justin Verlander J. Verlander	507	3,553	3,046	555	266	158	.627	555	3.32	26	9	0	3567.2	1,317	1,428	371	1,004	121	0	28	14,607	99	8.96	2.53	3.54	0.94	24.3	6.9	1.14	.280	3.60	79	3.43	81	7.68	310.9
18	Stephen Strasburg S. Strasburg	506	1,723	1,217	247	113	62	.646	247	3.24	2	2	0	1470.0	530	582	149	394	53	0	20	5,962	44	10.55	2.41	4.37	0.91	28.9	6.6	1.10	.293	3.56	80	3.01	75	7.45	165.9
19	Sam McDowell S. McDowell	505	2,453	1,948	425	141	134	.513	346	3.17	103	23	14	2492.1	879	999	164	1,312	59	39	74	10,587	140	8.86	4.74	1.87	0.59	23.2	12.4	1.31	.270	3.61	90	3.06	84	7.03	160.4
20	David Robertson D. Robertson	502	1,176	674	881	68	46	.596	1	2.93	0	0	179	894.1	291	315	81	365	25	358	38	3,690	57	11.83	3.67	3.22	0.82	31.9	9.9	1.16	.290	3.17	70	2.98	70	6.78	122.3
21	Kerry Wood K. Wood	499	1,582	1,083	446	86	75	.534	178	3.67	11	5	63	1380.0	563	599	148	666	99	138	22	5,863	64	10.32	4.34	2.38	0.97	27.0	11.4	1.27	.278	3.91	86	3.82	87	7.06	84
22	Roger Clemens R. Clemens	487	4,672	4,185	709	354	184	.658	707	3.12	118	46	0	4916.2	1,707	1,885	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	70	3.08	71	7.66	680.4
23	Robbie Ray R. Ray	484	1,734	1,250	265	88	81	.521	261	3.94	2	1	0	1441.0	631	674	216	608	51	1	19	6,097	60	10.83	3.80	2.85	1.35	28.4	10.0	1.29	.296	4.21	94	4.06	99	7.81	5.1
24	Edwin Díaz E. Díaz	483	839	356	520	28	36	.438	0	2.82	0	0	253	519.1	163	176	54	182	40	395	9	2,105	33	14.54	3.15	4.61	0.94	39.9	8.6	1.04	.305	3.05	70	2.55	61	6.17	93.4
25	Freddy Peralta F. Peralta	459	1,153	694	211	70	42	.625	162	3.59	1	0	1	931.0	371	392	118	360	48	6	3	3,853	31	11.15	3.48	3.20	1.14	29.9	9.3	1.13	.265	3.79	85	3.66	87	6.71	59.2