most strikeouts pitched in a game after 2000

Since 2001, Gerrit Cole, Ted Lilly and Clay Hensley are tied for the most strikeouts by a pitcher in a game, with 5 strikeouts.

Interpreted as:

most strikeouts by a player pitched in a regular-season game after 2000

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Gerrit Cole G. Cole	5	5/4/2018	HOU	@	ARI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
2	Ted Lilly T. Lilly	5	6/30/2008	CHC	@	SFG	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
3	Clay Hensley C. Hensley	5	5/14/2006	SDP	@	CHC	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
4	Carlos Hernández C. Hernández	4	8/22/2021	KCR	@	CHC	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
5	Eric Lauer E. Lauer	4	7/3/2021	MIL	@	PIT	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
6	Trevor Rogers T. Rogers	4	6/10/2021	MIA	vs	COL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
7	Tyler Anderson T. Anderson	4	5/9/2021	PIT	@	CHC	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
8	Tyler Beede T. Beede	4	7/2/2019	SFG	@	SDP	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
9	Jose Quintana J. Quintana	4	9/24/2017	CHC	@	MIL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
10	Martín Pérez M. Pérez	4	8/9/2017	TEX	@	NYM	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
11	Joe Ross J. Ross	4	7/4/2017	WSH	vs	NYM	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
12	Ivan Nova I. Nova	4	8/23/2016	PIT	vs	HOU	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
13	Adam Wainwright A. Wainwright	4	7/16/2016	STL	vs	MIA	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
14	Jeff Locke J. Locke	4	5/30/2016	PIT	@	MIA	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
15	Rubby De La Rosa R. De La Rosa	4	6/14/2015	ARI	@	SFG	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
16	Jake Arrieta J. Arrieta	4	5/12/2015	CHC	vs	NYM	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
17	Bartolo Colon B. Colon	4	8/8/2014	NYM	@	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
18	Lance Lynn L. Lynn	4	5/27/2014	STL	vs	NYY	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
19	Cliff Lee C. Lee	4	6/24/2013	PHI	@	SDP	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
20	Adam Wainwright A. Wainwright	4	5/11/2013	STL	vs	COL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
21	Shelby Miller S. Miller	4	5/10/2013	STL	vs	COL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
22	A.J. Burnett	4	7/31/2012	PIT	@	CHC	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
23	Matt Garza M. Garza	4	4/12/2012	CHC	vs	MIL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
24	Juan Nicasio J. Nicasio	4	7/1/2011	COL	vs	KCR	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
25	James Shields J. Shields	4	6/24/2011	TBR	@	HOU	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0