The Arizona Diamondbacks had their most strikeouts in a game versus the Cardinals on September 24, 2019, with 23 strikeouts.

Interpreted as:

most strikeouts in a regular-season game un dbacks history

	TEAM	SO	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Diamondbacks	23	9/24/2019	ARI	vs	STL	W 3-2	65	3	13	1	1	1	3	9	0	0	1	74	19	3	0	0	3	2	.200	.297	.292	.590
2	Diamondbacks	19	5/8/2019	ARI	@	TBR	W 3-2	44	3	9	1	0	0	3	8	0	0	0	52	10	1	0	0	0	3	.205	.327	.227	.554
3	Diamondbacks	18	7/8/2018	ARI	vs	SDP	L 3-4	57	3	11	4	0	0	3	4	2	1	0	63	15	4	0	0	0	3	.193	.270	.263	.533
4	Diamondbacks	18	6/5/2016	ARI	@	CHC	W 3-2	34	3	10	1	0	0	3	5	0	2	1	40	11	1	1	0	1	0	.294	.385	.324	.708
5	Diamondbacks	18	4/25/2007	ARI	vs	SDP	W 3-2	29	3	4	0	0	2	3	4	0	0	0	33	10	2	0	0	0	0	.138	.242	.345	.587
6	Diamondbacks	17	8/8/2021	ARI	@	SDP	L 0-2	30	0	3	2	0	0	0	3	0	0	0	33	5	2	0	0	0	0	.100	.182	.167	.348
7	Diamondbacks	17	9/28/2018	ARI	@	SDP	L 2-3	52	2	10	2	0	0	1	7	1	2	0	61	12	2	0	1	2	1	.192	.295	.231	.526
8	Diamondbacks	17	8/15/2017	ARI	vs	HOU	L 4-9	34	4	8	3	0	0	4	4	0	0	0	38	11	3	0	0	0	1	.235	.316	.324	.639
9	Diamondbacks	17	4/24/2016	ARI	vs	PIT	L 10-12	52	10	15	3	1	4	10	8	0	1	0	62	32	8	2	0	2	0	.288	.383	.615	.999
10	Diamondbacks	17	4/16/2016	ARI	@	SDP	L 3-5	52	3	11	4	0	0	2	4	1	0	0	58	15	4	0	1	1	0	.212	.276	.288	.564
11	Diamondbacks	16	4/17/2025	AZ	@	MIA	W 6-4	32	6	5	1	0	2	6	9	1	6	0	43	12	3	0	1	0	0	.156	.349	.375	.724
12	Diamondbacks	16	9/23/2022	ARI	vs	SFG	L 5-6	38	5	11	3	0	1	5	4	0	0	0	42	17	4	0	0	0	0	.289	.357	.447	.805
13	Diamondbacks	16	4/16/2022	ARI	@	NYM	W 3-2	36	3	9	2	0	1	3	4	0	2	0	40	14	3	0	0	2	0	.250	.325	.389	.714
14	Diamondbacks	16	10/1/2021	ARI	vs	COL	L 7-9	36	7	9	2	0	3	7	1	0	0	1	37	20	5	0	0	0	0	.250	.270	.556	.826
15	Diamondbacks	16	6/6/2021	ARI	@	MIL	L 0-2	33	0	6	1	0	0	0	0	0	0	0	33	7	1	0	0	0	0	.182	.182	.212	.394
16	Diamondbacks	16	4/21/2021	ARI	@	CIN	W 8-5	36	8	6	0	0	1	7	7	3	0	0	46	9	1	0	0	1	1	.167	.348	.250	.598
17	Diamondbacks	16	5/18/2018	ARI	@	NYM	L 1-3	32	1	6	2	0	0	1	0	0	0	0	32	8	2	0	0	0	0	.188	.188	.250	.438
18	Diamondbacks	16	5/4/2018	ARI	vs	HOU	L 0-8	28	0	1	1	0	0	0	1	0	0	0	29	2	1	0	0	0	0	.036	.069	.071	.140
19	Diamondbacks	16	7/16/2016	ARI	vs	LAD	W 2-1	39	2	8	2	1	0	2	4	0	1	2	43	12	3	0	0	3	0	.205	.279	.308	.587
20	Diamondbacks	16	5/8/2016	ARI	@	ATL	W 5-3	42	5	9	1	1	2	5	1	0	1	0	43	18	4	0	0	0	0	.214	.233	.429	.661
21	Diamondbacks	16	7/23/2015	ARI	vs	MIL	W 8-3	36	8	13	3	1	1	7	4	0	1	0	41	21	5	0	1	1	0	.361	.415	.583	.998
22	Diamondbacks	16	7/22/2015	ARI	vs	MIA	L 3-5	35	3	8	3	1	0	3	5	1	0	0	41	13	4	0	0	0	0	.229	.341	.371	.713
23	Diamondbacks	16	7/26/2012	ARI	vs	NYM	L 1-3	31	1	4	2	0	0	1	6	1	0	0	39	6	2	0	1	0	0	.129	.282	.194	.476
24	Diamondbacks	16	6/30/2012	ARI	@	MIL	L 2-10	33	2	6	0	0	1	2	4	0	1	0	37	9	1	0	0	0	0	.182	.270	.273	.543
25	Diamondbacks	16	7/21/2010	ARI	vs	NYM	W 4-3	52	4	12	2	0	3	4	7	1	1	0	60	23	5	0	0	2	0	.231	.333	.442	.776