Between the 2004 and 2006 seasons, Roy Oswalt and Johan Santana were tied for winning the most games, with 55 wins.

Interpreted as:

most regular-season wins by a player 2004 to 2006 MLB pitcher

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Roy Oswalt R. Oswalt	55	30	.647	104	102	3.14	556	8	3	0	699.1	696	244	261	53	148	25	1	12	2,881	11	7.16	1.90	3.76	0.68	19.3	5.1	1.21	.306	3.36	72	3.20	72	8.96	95.1
2	Johan Santana J. Santana	55	19	.743	101	101	2.75	748	5	3	0	693.1	522	212	226	70	146	14	0	1	2,714	19	9.71	1.90	5.12	0.91	27.6	5.4	0.96	.260	2.93	62	2.91	67	6.78	110.8
3	Chris Carpenter C. Carpenter	51	18	.739	93	93	3.10	549	13	7	0	645.1	567	222	238	63	132	21	0	5	2,595	12	7.66	1.84	4.16	0.88	21.2	5.1	1.08	.275	3.32	73	3.34	78	7.91	69.4
4	Randy Johnson R. Johnson	50	33	.602	102	102	3.73	673	10	2	0	676.1	578	280	315	78	151	32	0	4	2,744	9	8.96	2.01	4.46	1.04	24.5	5.5	1.08	.276	4.19	83	3.38	76	7.69	79.3
5	Kenny Rogers K. Rogers	49	25	.662	99	98	4.04	312	3	2	0	611.0	648	274	300	62	181	26	1	3	2,612	7	4.60	2.67	1.72	0.91	11.9	6.9	1.36	.289	4.42	86	4.38	97	9.55	10.3
6	Jon Garland J. Garland	48	28	.632	99	97	4.30	340	5	4	0	649.1	682	310	330	86	164	17	0	9	2,724	9	4.71	2.27	2.07	1.19	12.5	6.0	1.30	.282	4.57	92	4.57	98	9.45	8.1
7	Cliff Lee C. Lee	46	24	.657	98	98	4.50	433	2	0	0	581.2	606	291	318	81	191	19	0	5	2,522	13	6.70	2.96	2.27	1.25	17.2	7.6	1.37	.292	4.92	102	4.47	103	9.38	-9.8
8	Carlos Zambrano C. Zambrano	46	21	.687	97	97	3.14	600	3	1	0	647.0	506	226	252	55	282	37	0	11	2,713	22	8.35	3.92	2.13	0.77	22.1	10.4	1.22	.259	3.51	71	3.79	85	7.04	48.8
9	Mark Buehrle M. Buehrle	44	31	.587	100	100	3.95	412	8	2	0	686.0	744	301	342	89	139	18	0	11	2,863	2	5.41	1.82	2.96	1.17	14.4	4.9	1.29	.297	4.49	85	4.23	90	9.76	33.3
10	Freddy Garcia F. Garcia	44	28	.611	97	97	4.07	465	4	0	0	654.1	645	296	310	80	172	17	0	8	2,738	32	6.40	2.37	2.70	1.10	17.0	6.3	1.25	.282	4.26	88	4.10	89	8.87	37.9
11	Greg Maddux G. Maddux	44	40	.524	102	102	4.15	404	5	1	0	647.2	676	299	324	84	106	16	0	15	2,670	10	5.61	1.47	3.81	1.17	15.1	4.0	1.21	.287	4.50	94	4.07	91	9.39	28.4
12	Curt Schilling C. Schilling	44	21	.677	95	74	3.97	473	3	0	9	524.0	547	231	233	63	85	11	21	1	2,162	5	8.12	1.46	5.56	1.08	21.9	3.9	1.21	.316	4.00	85	3.38	77	9.40	58.7
13	Jeff Suppan J. Suppan	44	26	.629	95	95	3.95	328	0	0	0	572.1	605	251	291	70	197	23	0	8	2,482	18	5.16	3.10	1.66	1.10	13.2	7.9	1.40	.287	4.58	93	4.66	108	9.51	-23.7
14	Jake Westbrook J. Westbrook	44	34	.564	99	96	4.01	344	10	3	0	637.2	673	284	322	53	172	16	2	10	2,694	12	4.86	2.43	2.00	0.75	12.8	6.4	1.33	.294	4.54	91	3.95	91	9.50	27.1
15	Dontrelle Willis D. Willis	44	33	.571	100	100	3.47	469	13	6	0	656.2	657	253	284	52	199	35	0	17	2,783	10	6.43	2.73	2.36	0.71	16.9	7.2	1.30	.298	3.89	82	3.73	87	9.00	40.6
16	Derek Lowe D. Lowe	42	35	.545	103	102	4.15	374	3	2	0	622.2	668	287	348	57	181	18	1	5	2,686	9	5.41	2.62	2.07	0.82	13.9	6.7	1.36	.297	5.03	94	4.01	92	9.66	24.6
17	Jason Marquis J. Marquis	42	37	.532	98	97	4.60	334	3	1	0	602.2	642	308	336	90	214	31	0	5	2,612	18	4.99	3.20	1.56	1.34	12.8	8.2	1.42	.284	5.02	108	5.11	119	9.59	-56.2
18	Jose Contreras J. Contreras	41	25	.621	93	93	4.40	438	2	1	0	571.0	537	279	306	74	214	27	0	7	2,448	53	6.90	3.37	2.05	1.17	17.9	8.7	1.32	.273	4.82	95	4.48	97	8.46	8.7
19	John Lackey J. Lackey	41	29	.586	99	98	3.87	533	5	3	0	625.0	626	269	291	49	203	28	0	11	2,669	45	7.68	2.92	2.63	0.71	20.0	7.6	1.33	.311	4.19	87	3.49	80	9.01	62.4
20	Jason Schmidt J. Schmidt	41	23	.641	93	93	3.67	596	7	4	0	610.1	514	249	268	55	242	14	0	13	2,558	25	8.79	3.57	2.46	0.81	23.3	9.5	1.24	.278	3.95	85	3.54	83	7.58	50.1
21	Barry Zito B. Zito	41	34	.547	103	103	4.05	485	0	0	0	662.1	612	298	321	81	269	35	0	7	2,824	12	6.59	3.66	1.80	1.10	17.2	9.5	1.33	.272	4.36	92	4.56	103	8.32	-8.6
22	Josh Beckett J. Beckett	40	28	.588	88	88	4.12	476	3	2	0	540.0	481	247	267	66	186	23	0	6	2,251	21	7.93	3.10	2.56	1.10	21.1	8.3	1.24	.277	4.45	94	4.05	94	8.02	14.1
23	Bartolo Colon B. Colon	40	25	.615	77	77	4.32	346	3	1	0	487.1	501	234	254	75	125	9	0	1	2,054	4	6.39	2.31	2.77	1.39	16.8	6.1	1.28	.284	4.69	98	4.44	102	9.25	-5.8
24	Jon Lieber J. Lieber	40	32	.556	89	89	4.46	351	3	1	0	563.0	635	279	302	80	83	13	0	11	2,375	13	5.61	1.33	4.23	1.28	14.8	3.5	1.28	.300	4.83	100	4.17	93	10.15	20.5
25	Pedro Martinez P. Martinez	40	25	.615	87	87	3.62	572	5	2	0	566.2	460	228	240	64	147	30	0	5	2,296	8	9.08	2.33	3.89	1.02	24.9	6.4	1.07	.267	3.81	82	3.44	79	7.31	56.3