Since 1999, Justin Verlander has won the most games, with 262 wins.

Interpreted as:

most regular-season wins by a pitcher since 1999

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Justin Verlander J. Verlander	262	153	.631	540	540	3.33	3,476	26	9	0	3486.1	2,967	1,290	1,395	364	978	118	0	27	14,257	97	8.97	2.52	3.55	0.94	24.4	6.9	1.13	.279	3.60	79	3.43	81	7.66	305.6
2	CC Sabathia	251	161	.609	561	560	3.74	3,093	38	12	0	3577.1	3,404	1,485	1,623	382	1,099	123	0	44	14,989	74	7.78	2.76	2.81	0.96	20.6	7.3	1.26	.294	4.08	87	3.77	87	8.56	223.7
3	Bartolo Colon B. Colon	229	172	.571	515	504	4.10	2,311	31	11	0	3163.2	3,281	1,441	1,562	412	824	58	2	41	13,345	36	6.57	2.34	2.80	1.17	17.3	6.2	1.30	.295	4.44	95	4.15	96	9.33	57.3
4	Zack Greinke Z. Greinke	225	156	.591	586	541	3.49	2,979	17	5	1	3389.1	3,207	1,315	1,410	367	762	79	8	25	13,877	101	7.91	2.02	3.91	0.97	21.5	5.5	1.17	.293	3.74	83	3.51	85	8.52	235
5	Tim Hudson T. Hudson	222	133	.625	482	479	3.49	2,080	26	13	0	3126.2	2,957	1,213	1,319	248	917	124	0	84	13,005	84	5.99	2.64	2.27	0.71	16.0	7.1	1.24	.281	3.80	83	3.78	90	8.51	152.3
6	Clayton Kershaw C. Kershaw	216	94	.697	441	438	2.52	3,000	25	15	0	2787.1	2,133	779	854	233	692	44	1	28	10,999	105	9.69	2.23	4.34	0.75	27.3	6.3	1.01	.270	2.76	64	2.84	70	6.89	365.8
7	Max Scherzer M. Scherzer	215	112	.657	469	460	3.17	3,419	12	5	0	2891.0	2,358	1,017	1,090	338	759	112	2	20	11,680	79	10.64	2.36	4.50	1.05	29.3	6.5	1.08	.286	3.39	76	3.18	77	7.34	309
8	Mark Buehrle M. Buehrle	214	160	.572	518	493	3.81	1,870	33	10	0	3283.1	3,472	1,391	1,542	361	734	79	6	49	13,705	27	5.13	2.01	2.55	0.99	13.6	5.4	1.28	.292	4.23	87	4.11	93	9.52	111.9
9	Roy Halladay R. Halladay	202	105	.658	414	388	3.39	2,104	66	20	1	2735.1	2,637	1,031	1,131	234	590	81	6	28	11,234	56	6.92	1.94	3.57	0.77	18.7	5.3	1.18	.292	3.72	77	3.38	77	8.68	294.5
10	Jon Lester J. Lester	200	117	.631	452	451	3.66	2,488	15	4	0	2740.0	2,610	1,114	1,215	294	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
11	Adam Wainwright A. Wainwright	200	128	.610	478	411	3.53	2,202	28	11	3	2668.1	2,577	1,047	1,117	233	736	81	13	40	11,116	51	7.43	2.48	2.99	0.79	19.8	6.6	1.24	.298	3.77	88	3.53	87	8.69	152.8
12	Andy Pettitte A. Pettitte	189	118	.616	397	394	3.88	1,860	12	3	0	2463.1	2,577	1,063	1,185	223	744	42	1	36	10,482	43	6.80	2.72	2.50	0.81	17.7	7.1	1.35	.309	4.33	87	3.71	83	9.42	204.2
13	John Lackey J. Lackey	188	147	.561	448	446	3.92	2,294	18	8	0	2840.1	2,862	1,237	1,347	319	815	133	0	32	12,030	125	7.27	2.58	2.81	1.01	19.1	6.8	1.29	.300	4.27	92	3.94	94	9.07	79.6
14	Derek Lowe D. Lowe	171	142	.546	598	358	3.97	1,593	10	4	82	2479.1	2,559	1,093	1,219	201	729	70	159	59	10,533	45	5.78	2.65	2.19	0.73	15.1	6.9	1.33	.297	4.42	93	3.81	90	9.29	128.3
15	Felix Hernandez F. Hernandez	169	136	.554	419	418	3.42	2,524	25	11	0	2729.2	2,487	1,037	1,157	264	805	105	0	16	11,284	156	8.32	2.65	3.14	0.87	22.4	7.1	1.21	.293	3.81	84	3.52	85	8.20	181.5
16	Barry Zito B. Zito	165	143	.536	433	421	4.04	1,885	12	5	0	2576.2	2,381	1,157	1,254	282	1,064	97	9	52	11,001	50	6.58	3.72	1.77	0.98	17.1	9.7	1.34	.274	4.38	97	4.38	104	8.32	-43.1
17	Jamie Moyer J. Moyer	165	116	.587	382	376	4.26	1,414	17	4	0	2373.2	2,438	1,123	1,201	324	636	97	2	34	10,073	24	5.36	2.41	2.22	1.23	14.0	6.3	1.30	.278	4.55	97	4.59	104	9.24	-47.8
18	A.J. Burnett	164	157	.511	435	430	3.99	2,513	24	10	0	2731.1	2,519	1,210	1,328	263	1,100	143	1	35	11,665	161	8.28	3.62	2.28	0.87	21.5	9.4	1.32	.295	4.38	97	3.86	92	8.30	97.3
19	Cole Hamels C. Hamels	163	122	.572	423	422	3.43	2,560	17	7	0	2698.0	2,424	1,027	1,103	310	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
20	Roy Oswalt R. Oswalt	163	102	.615	365	341	3.36	1,852	20	8	0	2245.1	2,199	838	897	197	520	80	7	34	9,301	30	7.42	2.08	3.56	0.79	19.9	5.6	1.21	.301	3.60	79	3.36	78	8.81	236.2
21	Randy Johnson R. Johnson	160	87	.648	322	316	3.23	2,546	44	14	0	2157.0	1,823	774	876	242	554	98	3	25	8,765	38	10.62	2.31	4.60	1.01	29.0	6.3	1.10	.297	3.66	72	3.07	69	7.61	332.5
22	Javier Vazquez J. Vazquez	160	145	.525	417	411	4.10	2,397	28	8	0	2667.2	2,588	1,215	1,310	342	695	77	4	56	11,171	74	8.09	2.34	3.45	1.15	21.5	6.2	1.23	.293	4.42	93	3.81	86	8.73	182.2
23	Livan Hernandez L. Hernandez	159	162	.495	468	424	4.46	1,740	41	9	1	2855.1	3,176	1,415	1,514	320	922	69	17	77	12,358	37	5.48	2.91	1.89	1.01	14.1	7.5	1.44	.307	4.77	105	4.35	102	10.01	-25.3
24	David Price D. Price	157	82	.657	400	322	3.32	2,076	17	3	3	2143.2	1,930	790	865	221	562	63	19	16	8,807	40	8.72	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
25	Freddy Garcia F. Garcia	156	108	.591	376	357	4.15	1,621	12	4	0	2264.0	2,243	1,045	1,101	285	708	67	13	42	9,595	95	6.44	2.81	2.29	1.13	16.9	7.4	1.30	.283	4.38	94	4.29	96	8.92	43.9