Walter Johnson has the most career wins when pitching fewer than 50 innings, with 417 wins.

Interpreted as:

most regular-season wins by a player with under 50 ip

	NAME	W	IP	L	W%	G	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Walter Johnson W. Johnson	417	5916.2	279	.599	802	666	1.70	3,527	531	110	34	4,917		1,902	97	1,374	208	128			155	5.37	2.09	2.57	0.15		5.8	1.06	.262	2.89	7.48
2	Grover Alexander G. Alexander	373	5182.2	208	.642	696	600	2.41	2,209	437	90	33	4,866		1,851	165	951	67	80		20,919	38	3.84	1.65	2.32	0.29	10.6	4.5	1.12	.268	3.21	8.45
3	Christy Mathewson C. Mathewson	373	4754.1	185	.668	630	551	0.97	2,512	434	79	25	4,182		1,585	88	827	54	70			109	4.76	1.57	3.04	0.17		4.4	1.05	.268	3.00	7.92
4	Warren Spahn W. Spahn	363	5243.2	245	.597	750	665	3.09	2,583	382	63	28	4,833	1,801	2,018	434	1,432	41	67	59	21,555	78	4.43	2.46	1.80	0.74	12.0	6.6	1.19	.258	3.46	8.30
5	Greg Maddux G. Maddux	355	5008.1	227	.610	744	740	3.16	3,371	109	35	0	4,726	1,756	1,981	353	999	137	3	177	20,421	70	6.06	1.80	3.37	0.63	16.5	4.9	1.14	.281	3.56	8.49
6	Roger Clemens R. Clemens	354	4916.2	184	.658	709	707	3.12	4,672	118	46	0	4,185	1,707	1,885	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	7.66
7	Steve Carlton S. Carlton	329	5217.2	244	.574	741	709	3.22	4,136	254	55	2	4,672	1,864	2,130	414	1,833	53	13	150	21,682	183	7.13	3.16	2.26	0.71	19.1	8.5	1.25	.279	3.67	8.06
8	Eddie Plank E. Plank	326	4488.2	194	.627	623	529	1.36	2,268	410	69	23	3,960		1,566	42	1,076	188	78			86	4.55	2.16	2.11	0.08		6.4	1.12	.294	3.14	7.94
9	Nolan Ryan N. Ryan	324	5386.0	292	.526	807	773	3.19	5,714	222	61	3	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	6.56
10	Don Sutton D. Sutton	324	5282.1	256	.559	774	756	3.26	3,574	178	58	5	4,692	1,914	2,104	472	1,343	82	12	103	21,631	112	6.09	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.58	7.99
11	Phil Niekro P. Niekro	318	5404.0	274	.537	864	716	3.35	3,342	245	45	29	5,044	2,012	2,337	482	1,809	123	83	86	22,677	227	5.57	3.01	1.85	0.80	14.7	8.0	1.27	.270	3.89	8.40
12	Gaylord Perry G. Perry	314	5350.0	265	.542	777	690	3.11	3,534	303	53	10	4,938	1,846	2,128	399	1,378	108	33	163	21,953	160	5.95	2.32	2.56	0.67	16.1	6.3	1.18	.275	3.58	8.31
13	Tom Seaver T. Seaver	311	4783.0	205	.603	656	647	2.86	3,640	231	61	1	3,971	1,521	1,674	380	1,390	76	6	117	19,369	125	6.85	2.62	2.62	0.72	18.8	7.2	1.12	.259	3.15	7.47
14	Tom Glavine T. Glavine	305	4413.1	203	.600	682	682	3.54	2,607	56	25	0	4,298	1,734	1,900	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	8.76
15	Randy Johnson R. Johnson	303	4135.1	166	.646	618	603	3.29	4,875	100	37	2	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	7.28
16	Early Wynn E. Wynn	300	4564.0	244	.551	691	611	3.54	2,340	289	49	15	4,292	1,793	2,037	339	1,775	64	67	36	19,406	53	4.61	3.50	1.32	0.67	12.1	9.1	1.33	.266	4.02	8.46
17	Lefty Grove L. Grove	300	3938.1	141	.680	616	457	3.06	2,269	298	35	54	3,848	1,341	1,596	162	1,184	41	123		16,622	51	5.19	2.71	1.92	0.37	13.7	7.1	1.28	.284	3.65	8.79
18	Tommy John T. John	288	4710.0	231	.555	760	700	3.34	2,245	162	46	3	4,783	1,749	2,017	302	1,259	98	22	102	19,691	188	4.29	2.41	1.78	0.58	11.4	6.4	1.28	.284	3.85	9.14
19	Bert Blyleven B. Blyleven	287	4970.0	250	.534	692	685	3.31	3,701	242	60	0	4,632	1,830	2,029	430	1,322	155	3	71	20,492	114	6.70	2.39	2.80	0.78	18.1	6.5	1.20	.282	3.67	8.39
20	Robin Roberts R. Roberts	286	4688.2	245	.539	676	609	3.40	2,362	305	45	25	4,582	1,773	1,962	505	901	54	49	71	19,222	34	4.53	1.73	2.62	0.97	12.3	4.7	1.17	.265	3.77	8.80
21	Fergie Jenkins F. Jenkins	284	4500.2	226	.557	664	594	3.34	3,191	267	49	7	4,142	1,669	1,853	484	997	84	37	117	18,404	62	6.38	1.99	3.20	0.97	17.3	5.4	1.14	.268	3.71	8.28
22	Jim Kaat J. Kaat	283	4530.0	237	.544	898	625	3.45	2,462	180	31	17	4,620	1,738	2,038	395	1,083	122	102	117	19,026	128	4.89	2.15	2.27	0.78	12.9	5.7	1.26	.282	4.05	9.18
23	Red Ruffing R. Ruffing	273	4341.1	225	.548	624	538	3.80	1,990	335	45	18	4,288	1,835	2,117	254	1,542	57	69		18,525	46	4.13	3.20	1.29	0.53	10.7	8.3	1.34	.275	4.39	8.89
24	Mike Mussina M. Mussina	270	3562.2	153	.638	537	536	3.68	2,813	57	23	0	3,460	1,458	1,559	376	785	60	0	29	14,593	71	7.11	1.98	3.58	0.95	19.3	5.4	1.19	.292	3.94	8.74
25	Burleigh Grimes B. Grimes	270	4177.0	212	.560	616	496	3.54	1,521	314	35	17	4,420	1,644	2,048	149	1,297	97	94		17,974	92	3.28	2.79	1.17	0.32	8.5	7.2	1.37	.286	4.41	9.52