Since 2005, Justin Verlander has won the most games, with 266 wins.

Interpreted as:

most regular-season wins by a player since 2005

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Justin Verlander J. Verlander	266	158	.627	555	555	3.32	3,553	26	9	0	3567.2	3,046	1,317	1,428	371	1,004	121	0	28	14,607	99	8.96	2.53	3.54	0.94	24.3	6.9	1.14	.280	3.60	79	3.43	81	7.68	310.9
2	Clayton Kershaw C. Kershaw	223	96	.699	455	451	2.53	3,052	25	15	0	2855.1	2,193	804	881	235	713	46	1	28	11,279	108	9.62	2.25	4.28	0.74	27.1	6.3	1.02	.271	2.78	65	2.85	70	6.91	375.1
3	Max Scherzer M. Scherzer	220	117	.653	483	474	3.22	3,489	12	5	0	2963.0	2,433	1,059	1,132	354	779	114	2	20	11,987	80	10.60	2.37	4.48	1.08	29.1	6.5	1.08	.287	3.44	77	3.23	78	7.39	302.5
4	Zack Greinke Z. Greinke	217	145	.599	562	517	3.47	2,879	17	5	1	3244.1	3,064	1,251	1,346	341	736	71	8	22	13,278	100	7.99	2.04	3.91	0.95	21.7	5.5	1.17	.294	3.73	83	3.46	84	8.50	236.2
5	Jon Lester J. Lester	200	117	.631	452	451	3.66	2,488	15	4	0	2740.0	2,610	1,114	1,215	294	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
6	Adam Wainwright A. Wainwright	200	128	.610	478	411	3.53	2,202	28	11	3	2668.1	2,577	1,047	1,117	233	736	81	13	40	11,116	51	7.43	2.48	2.99	0.79	19.8	6.6	1.24	.298	3.77	88	3.53	87	8.69	152.8
7	CC Sabathia	197	126	.610	435	434	3.63	2,493	33	10	0	2801.1	2,691	1,130	1,246	307	778	102	0	35	11,716	56	8.01	2.50	3.20	0.99	21.3	6.6	1.24	.297	4.00	85	3.70	86	8.65	194.7
8	Felix Hernandez F. Hernandez	169	136	.554	419	418	3.42	2,524	25	11	0	2729.2	2,487	1,037	1,157	264	805	105	0	16	11,284	156	8.32	2.65	3.14	0.87	22.4	7.1	1.21	.293	3.81	84	3.52	85	8.20	181.5
9	Cole Hamels C. Hamels	163	122	.572	423	422	3.43	2,560	17	7	0	2698.0	2,424	1,027	1,103	310	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
10	David Price D. Price	157	82	.657	400	322	3.32	2,076	17	3	3	2143.2	1,930	790	865	221	562	63	19	16	8,807	40	8.72	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
11	John Lackey J. Lackey	155	114	.576	364	363	3.81	1,930	14	5	0	2329.2	2,311	985	1,070	256	656	111	0	24	9,825	96	7.46	2.53	2.94	0.99	19.6	6.7	1.27	.299	4.13	90	3.87	94	8.93	71.1
12	Gerrit Cole G. Cole	153	80	.657	317	317	3.18	2,251	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
13	Ervin Santana E. Santana	151	129	.539	425	386	4.11	1,978	21	11	0	2486.2	2,391	1,135	1,221	331	776	104	20	35	10,482	104	7.16	2.81	2.55	1.20	18.9	7.4	1.27	.282	4.42	99	4.31	104	8.65	-44.1
14	Rick Porcello R. Porcello	150	125	.545	355	351	4.40	1,561	10	3	0	2096.1	2,270	1,025	1,122	260	489	84	2	17	8,912	70	6.70	2.10	3.19	1.12	17.5	5.5	1.32	.308	4.82	102	4.06	97	9.75	26.3
15	Jered Weaver J. Weaver	150	98	.605	331	331	3.63	1,621	14	8	0	2067.1	1,912	833	879	262	551	55	0	17	8,531	37	7.06	2.40	2.94	1.14	19.0	6.5	1.19	.273	3.83	89	4.06	99	8.32	5.6
16	Charlie Morton C. Morton	147	134	.523	416	409	4.13	2,196	3	2	0	2267.2	2,143	1,040	1,139	226	859	200	1	27	9,755	72	8.72	3.41	2.56	0.90	22.5	8.8	1.32	.306	4.52	103	3.89	97	8.51	36.6
17	Dan Haren D. Haren	147	121	.549	363	361	3.70	1,938	16	6	1	2301.0	2,228	945	1,038	292	461	60	2	37	9,507	94	7.58	1.80	4.20	1.14	20.4	4.8	1.17	.287	4.06	91	3.74	92	8.71	94
18	Chris Sale C. Sale	145	88	.622	393	312	3.01	2,579	16	3	12	2084.0	1,692	697	750	213	487	130	25	15	8,389	48	11.14	2.10	5.30	0.92	30.7	5.8	1.05	.297	3.24	70	2.87	68	7.31	303.3
19	James Shields J. Shields	145	139	.511	407	405	4.01	2,234	23	9	0	2616.0	2,581	1,167	1,267	361	746	97	1	22	10,993	107	7.69	2.57	2.99	1.24	20.3	6.8	1.27	.294	4.36	98	4.16	101	8.88	-13.5
20	Mark Buehrle M. Buehrle	145	115	.558	354	354	3.84	1,289	18	5	0	2296.0	2,486	979	1,081	252	494	52	0	35	9,617	19	5.05	1.94	2.61	0.99	13.4	5.1	1.30	.297	4.24	89	4.11	96	9.74	50.3
21	Johnny Cueto J. Cueto	144	113	.560	370	365	3.52	1,857	18	8	0	2256.1	2,094	883	955	253	637	120	1	22	9,373	36	7.41	2.54	2.92	1.01	19.8	6.8	1.21	.283	3.81	86	3.93	96	8.35	31.8
22	Lance Lynn L. Lynn	143	99	.591	364	340	3.74	2,015	4	2	1	2006.1	1,856	834	916	231	704	89	4	21	8,520	61	9.04	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
23	Roy Halladay R. Halladay	136	66	.673	251	250	3.11	1,415	52	14	0	1774.2	1,661	613	657	149	311	57	0	19	7,160	28	7.18	1.58	4.55	0.76	19.8	4.3	1.11	.289	3.33	74	3.22	76	8.42	202.4
24	Madison Bumgarner M. Bumgarner	134	124	.519	358	355	3.47	2,070	16	7	0	2209.1	2,007	853	933	258	544	89	1	38	9,098	29	8.43	2.22	3.81	1.05	22.8	6.0	1.15	.285	3.80	90	3.62	94	8.18	50.1
25	J.A. Happ	133	100	.571	354	328	4.13	1,661	4	3	0	1893.2	1,822	868	919	261	668	41	10	16	8,048	47	7.89	3.17	2.49	1.24	20.6	8.3	1.31	.288	4.37	100	4.28	103	8.66	-23.1