Walter Johnson has the most career wins when scoring 1+ run, with 150 wins.

Interpreted as:

most regular-season wins when scoring 1 or more run by a player

	NAME	W	R	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Walter Johnson W. Johnson	150	240	32	.824	201	182	1.61	936	147	27	6	1605.0	1,355		25	335	55	16			43	5.25	1.88	2.79	0.14		5.2	1.05	.260	2.79	7.60
2	Christy Mathewson C. Mathewson	118	152	11	.915	132	122	0.99	520	97	19	2	1051.2	932		17	181	11	9			19	4.45	1.55	2.87	0.15		4.3	1.06	.264	2.64	7.98
3	Grover Alexander G. Alexander	116	154	13	.899	135	130	2.04	519	117	21	1	1175.1	1,035		30	214	12	5		4,688	6	3.97	1.64	2.43	0.23	11.1	4.6	1.06	.257	2.76	7.93
4	Red Ruffing R. Ruffing	113	207	32	.779	171	161	3.53	638	116	14	2	1362.1	1,321	534	72	461	12	8		5,776	13	4.21	3.05	1.38	0.48	11.0	8.0	1.31	.272	4.08	8.73
5	Wes Ferrell W. Ferrell	99	175	18	.846	129	122	3.42	394	101	9	1	1041.1	1,087	396	58	382	10	6		4,521	9	3.41	3.30	1.03	0.50	8.7	8.4	1.41	.280	3.96	9.39
6	Eddie Plank E. Plank	97	130	15	.866	118	112	1.24	501	104	12	0	1025.2	885		9	219	48	5			20	4.40	1.92	2.29	0.08		5.7	1.08	.283	2.83	7.77
7	Warren Spahn W. Spahn	96	141	15	.865	124	122	2.76	535	94	12	1	1027.1	928	315	86	267	4	2	9	4,198	15	4.69	2.34	2.00	0.75	12.7	6.4	1.16	.255	3.14	8.13
8	Burleigh Grimes B. Grimes	90	157	23	.796	127	119	3.33	370	93	9	1	1042.0	1,091		37	307	29	7		4,472	19	3.20	2.65	1.21	0.32	8.3	6.9	1.34	.283	4.33	9.42
9	Ted Lyons T. Lyons	89	162	26	.774	121	115	3.13	271	101	6	2	1034.0	989	360	47	238	3	6		4,248	8	2.36	2.07	1.14	0.41	6.4	5.6	1.19	.255	3.64	8.61
10	Steve Carlton S. Carlton	87	123	10	.897	107	106	2.62	737	55	13	1	856.1	683	249	53	259	6	1	12	3,452	34	7.75	2.72	2.85	0.56	21.3	7.5	1.10	.263	2.89	7.18
11	Early Wynn E. Wynn	87	136	23	.791	123	117	2.82	513	69	13	1	971.1	864	304	60	369	15	5	4	4,065	9	4.75	3.42	1.39	0.56	12.6	9.1	1.27	.259	3.20	8.01
12	Cy Young C. Young	87	115	7	.926	96	88	1.02	411	88	15	1	844.0	690		10	92	17	8			8	4.38	0.98	4.47	0.11		3.0	0.93	.263	2.32	7.36
13	George Mullin G. Mullin	85	162	38	.691	135	127	1.27	420	108	7	1	1101.2	1,056		15	392	42	8			19	3.43	3.20	1.07	0.12		9.0	1.31	.300	4.08	8.63
14	Bob Gibson B. Gibson	83	132	11	.883	106	106	2.41	706	70	18	0	879.1	690	235	50	291	26	0	15	3,575	18	7.23	2.98	2.43	0.51	19.7	8.1	1.12	.256	2.73	7.06
15	George Uhle G. Uhle	82	173	24	.774	128	114	3.39	353	86	9	1	992.1	1,047		33	263	34	11		4,241	18	3.20	2.39	1.34	0.30	8.3	6.2	1.32	.285	4.09	9.50
16	Bob Lemon B. Lemon	80	148	12	.870	109	100	2.87	383	65	11	2	852.2	712	272	50	387	16	6		3,586	14	4.04	4.08	0.99	0.53	10.7	10.8	1.29	.241	3.28	7.52
17	Lefty Grove L. Grove	80	119	10	.889	106	99	2.92	510	70	8	2	832.2	800	270	38	254	4	7		3,510	9	5.51	2.75	2.01	0.41	14.5	7.2	1.27	.282	3.39	8.65
18	Bullet Joe Bush B. Joe Bush	80	130	14	.851	109	95	2.94	361	74	12	1	865.2	812		21	316	6	12			21	3.75	3.29	1.14	0.22		8.7	1.30	.268	3.60	8.44
19	Sad Sam Jones S. Sam Jones	79	152	22	.782	117	108	3.27	281	78	9	3	910.0	925		33	293	13	8			14	2.78	2.90	0.96	0.33		7.6	1.34	.274	4.16	9.15
20	Bucky Walters B. Walters	77	227	22	.778	119	115	3.27	341	79	10	0	960.0	899	349	48	349	13	1		4,036	20	3.20	3.27	0.98	0.45	8.4	8.6	1.30	.259	3.74	8.43
21	Carl Mays C. Mays	77	112	7	.917	98	87	2.38	224	75	12	2	794.2	739	210	21	152	21	8		3,219	6	2.54	1.72	1.47	0.24	7.0	4.7	1.12	.256	2.94	8.37
22	Greg Maddux G. Maddux	72	103	6	.923	96	96	2.77	487	20	6	0	673.2	590	207	42	109	18	0	13	2,691	11	6.51	1.46	4.47	0.56	18.1	4.1	1.04	.269	3.14	7.88
23	Wilbur Cooper W. Cooper	72	111	14	.837	94	91	2.48	265	75	9	0	808.2	758		18	153	24	3			10	2.95	1.70	1.73	0.20		4.7	1.13	.264	3.04	8.44
24	Carl Hubbell C. Hubbell	71	95	9	.888	90	87	2.60	364	67	9	2	739.2	692	214	38	109	19	3		3,014	9	4.43	1.33	3.34	0.46	12.1	3.6	1.08	.263	3.07	8.42
25	Bill Donovan B. Donovan	71	130	17	.807	95	89	1.38	425	82	11	1	829.0	771		7	291	22	6			16	4.61	3.16	1.46	0.08		9.0	1.28	.306	3.50	8.37