Between the 2000 and 2009 seasons, Daniel Cabrera fanned the most batters for the Orioles, with 651 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Daniel Cabrera D. Cabrera	651	147	48	59	.449	146	5.05	6	2	1	841.1	825	472	501	88	478	51	1	16	3,783	60	6.96	5.11	1.36	0.94	17.2	12.6	1.55	.293	5.36	113	4.81	106	8.83	-22
2	Erik Bedard E. Bedard	639	114	40	34	.541	111	3.83	1	1	0	658.0	627	280	308	58	254	22	0	2	2,820	20	8.74	3.47	2.52	0.79	22.7	9.0	1.34	.308	4.21	85	3.58	78	8.58	72.3
3	Sidney Ponson S. Ponson	639	160	53	64	.453	160	4.84	22	4	0	1030.1	1,145	554	590	126	343	24	0	7	4,465	34	5.58	3.00	1.86	1.10	14.3	7.7	1.44	.306	5.15	109	4.46	97	10.00	14.8
4	Rodrigo Lopez R. Lopez	614	167	60	58	.508	141	4.72	5	2	0	912.2	990	479	510	128	281	28	5	15	3,951	19	6.05	2.77	2.19	1.26	15.5	7.1	1.39	.297	5.03	107	4.53	100	9.76	1.9
5	B.J. Ryan	436	391	15	19	.441	0	3.57	0	0	42	361.0	294	143	154	29	182	12	128	20	1,552	13	10.87	4.54	2.40	0.72	28.1	11.7	1.32	.297	3.84	80	3.27	72	7.33	50.3
6	Jason Johnson J. Johnson	408	111	26	46	.361	99	4.73	3	0	0	624.2	670	328	372	90	259	33	3	15	2,776	23	5.88	3.73	1.58	1.30	14.7	9.3	1.49	.292	5.36	107	5.00	110	9.65	-31.5
7	Jeremy Guthrie J. Guthrie	353	95	27	34	.443	89	4.15	2	0	0	566.0	565	261	280	82	165	20	3	5	2,393	12	5.61	2.62	2.14	1.30	14.8	6.9	1.29	.272	4.45	92	4.76	105	8.98	-12
8	Jorge Julio J. Julio	257	281	11	24	.314	0	4.20	0	0	83	291.2	275	136	156	42	133	10	189	15	1,280	26	7.93	4.10	1.93	1.30	20.1	10.4	1.40	.278	4.81	96	4.59	102	8.49	-2.1
9	Bruce Chen B. Chen	235	82	15	18	.455	51	4.61	2	0	0	343.2	363	176	194	68	114	9	16	3	1,481	3	6.15	2.99	2.06	1.78	15.9	7.7	1.39	.280	5.08	104	5.33	117	9.51	-29
10	Buddy Groom B. Groom	212	330	15	13	.536	0	3.91	0	0	18	285.1	296	124	133	26	72	7	108	8	1,207	4	6.69	2.27	2.94	0.82	17.6	6.0	1.29	.303	4.20	87	3.57	78	9.34	31.9
11	Mike Mussina M. Mussina	210	34	11	15	.423	34	3.79	6	1	0	237.2	236	100	105	28	46	3	0	0	987	3	7.95	1.74	4.57	1.06	21.3	4.7	1.19	.297	3.98	80	3.51	73	8.94	34.7
12	John Parrish J. Parrish	195	153	12	12	.500	10	4.52	0	0	1	219.0	207	110	127	20	165	10	37	14	1,018	18	8.01	6.78	1.18	0.82	19.2	16.2	1.70	.298	5.22	100	4.89	106	8.51	-6.5
13	Jose Mercedes J. Mercedes	193	69	22	24	.478	51	5.02	3	0	0	329.2	369	184	196	35	127	13	8	4	1,464	8	5.27	3.47	1.52	0.96	13.2	8.7	1.50	.305	5.35	113	4.56	99	10.07	2.4
14	Chris Ray C. Ray	177	191	10	17	.370	0	4.11	0	0	49	192.2	178	88	95	28	86	5	113	14	834	3	8.27	4.02	2.06	1.31	21.2	10.3	1.37	.279	4.44	91	4.59	100	8.31	0
15	Willis Roberts W. Roberts	172	138	17	15	.531	18	4.57	1	0	7	246.1	262	125	135	27	103	22	53	6	1,101	12	6.28	3.76	1.67	0.99	15.6	9.4	1.48	.302	4.93	106	4.56	102	9.57	-2.6
16	Brian Burres B. Burres	165	79	13	18	.419	39	5.88	0	0	0	258.2	311	169	173	32	117	11	12	3	1,186	11	5.74	4.07	1.41	1.11	13.9	9.9	1.65	.324	6.02	132	4.99	110	10.82	-12.4
17	Rick Bauer R. Bauer	146	125	8	13	.381	9	4.57	0	0	1	240.0	239	122	139	30	93	13	34	7	1,030	11	5.48	3.49	1.57	1.13	14.2	9.0	1.38	.279	5.21	104	4.74	105	8.96	-6
18	Pat Hentgen P. Hentgen	144	41	9	15	.375	35	4.26	2	0	1	245.0	232	116	119	38	87	5	2	4	1,031	6	5.29	3.20	1.66	1.40	14.0	8.4	1.30	.256	4.37	98	4.99	111	8.52	-12.5
19	Adam Loewen A. Loewen	134	35	8	8	.500	29	5.38	0	0	0	164.0	163	98	105	14	106	11	1	0	749	6	7.35	5.82	1.26	0.77	17.9	14.2	1.64	.308	5.76	118	4.77	104	8.95	-2.5
20	Mike Trombley M. Trombley	117	125	7	9	.438	0	3.84	0	0	10	126.2	105	54	57	19	65	6	53	10	548	9	8.31	4.62	1.80	1.35	21.4	11.9	1.34	.252	4.05	84	4.87	104	7.46	-2.9
21	Eric DuBose E. DuBose	115	52	9	15	.375	27	5.21	1	0	0	188.1	181	109	116	25	92	10	7	2	826	6	5.50	4.40	1.25	1.19	13.9	11.1	1.45	.267	5.54	117	5.16	113	8.65	-11.7
22	Scott Erickson S. Erickson	115	45	10	20	.333	44	6.39	4	1	0	253.1	319	180	190	34	116	13	0	2	1,165	8	4.09	4.12	0.99	1.21	9.9	10.0	1.72	.321	6.75	142	5.38	118	11.33	-23
23	Garrett Olson G. Olson	111	33	10	13	.435	33	6.87	0	0	0	165.0	210	126	128	21	90	10	0	2	783	7	6.05	4.91	1.23	1.15	14.2	11.5	1.82	.343	6.98	154	5.27	117	11.45	-13.3
24	Travis Driskill T. Driskill	111	49	11	13	.458	19	5.23	0	0	1	180.2	212	105	113	29	57	9	12	3	804	9	5.53	2.84	1.95	1.44	13.8	7.1	1.49	.306	5.63	120	4.93	111	10.56	-9.5
25	Dennis Sarfate D. Sarfate	106	77	4	4	.500	4	4.82	0	0	0	102.2	83	55	62	11	76	8	20	2	460	6	9.29	6.66	1.39	0.96	23.0	16.5	1.55	.278	5.44	108	4.90	109	7.28	-4.1