The San Diego Padres scored their most runs in a game against the Nationals on July 16, 2021, with 24 runs.

Interpreted as:

padres most highest scoring regular-season game

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Padres	24	7/16/2021	SDP	@	WSH	W 24-8	50	22	3	1	5	23	9	0	7	3	0	60	42	9	1	0	0	0	.440	.525	.840	1.365
2	Padres	21	5/10/2025	SDP	@	COL	W 21-0	50	24	4	1	5	20	5	0	4	0	0	56	45	10	0	1	0	0	.480	.518	.900	1.418
3	Padres	20	5/19/2001	SDP	@	MON	W 20-7	46	20	3	0	4	19	7	2	4	1	0	57	35	7	1	1	0	0	.435	.518	.761	1.279
4	Padres	20	7/27/1996	SDP	@	FLA	W 20-12	47	19	4	0	3	20	8	0	10	1	0	55	32	7	0	0	0	0	.404	.491	.681	1.172
5	Padres	19	6/15/2022	SDP	@	CHC	W 19-5	46	21	7	1	3	19	6	2	5	0	0	55	39	11	0	1	1	1	.457	.527	.848	1.375
6	Padres	19	5/25/2019	SDP	@	TOR	W 19-4	45	20	2	0	7	19	6	3	11	1	0	54	43	9	0	0	0	2	.444	.537	.956	1.493
7	Padres	18	5/31/2010	SDP	vs	NYM	W 18-6	37	19	2	0	2	17	8	1	3	0	0	48	27	4	1	1	0	3	.514	.596	.730	1.325
8	Padres	18	7/29/2007	SDP	@	HOU	W 18-11	47	19	6	0	3	17	5	0	8	0	0	53	34	9	0	1	1	0	.404	.453	.723	1.176
9	Padres	18	8/23/2002	SDP	vs	FLA	W 18-2	44	18	0	0	3	13	5	0	6	1	0	49	27	3	0	0	0	0	.409	.469	.614	1.083
10	Padres	17	4/12/2010	SDP	vs	ATL	W 17-2	44	19	5	1	2	17	5	0	7	1	0	49	32	8	0	0	0	0	.432	.490	.727	1.217
11	Padres	17	6/7/1998	SDP	@	TEX	W 17-8	40	15	4	0	1	17	9	0	0	0	1	49	22	5	0	0	1	1	.375	.490	.550	1.040
12	Padres	17	4/7/1996	SDP	@	HOU	W 17-2	47	17	6	0	3	16	6	1	8	0	1	54	32	9	0	0	0	0	.362	.444	.681	1.125
13	Padres	17	8/24/1993	SDP	vs	STL	W 17-4	38	14	4	1	5	17	5	0	3	0	0	44	35	10	0	1	0	0	.368	.432	.921	1.353
14	Padres	17	7/18/1989	SDP	vs	PIT	W 17-4	43	22	2	0	3	17	7	0	4	1	0	51	33	5	0	1	1	0	.512	.569	.767	1.336
15	Padres	17	5/23/1970	SDP	@	SFG	W 17-16	63	21	3	0	5	15	12	1	11	0	0	79	39	8	3	0	2	0	.333	.447	.619	1.066
16	Padres	16	4/29/2023	SDP	vs	SFG	W 16-11	41	17	5	0	6	14	10	0	11	3	0	51	40	11	0	0	1	0	.415	.529	.976	1.505
17	Padres	16	5/21/2021	SDP	vs	SEA	W 16-1	40	17	2	1	3	16	6	0	8	2	0	46	30	6	0	0	0	1	.425	.500	.750	1.250
18	Padres	16	6/14/2019	SDP	@	COL	W 16-12	56	21	5	1	4	15	6	0	10	1	0	62	40	10	0	0	0	1	.375	.435	.714	1.150
19	Padres	16	4/9/2016	SDP	@	COL	W 16-3	44	19	2	0	4	16	6	0	8	0	1	50	33	6	0	0	0	2	.432	.500	.750	1.250
20	Padres	16	8/10/2008	SDP	@	COL	W 16-7	45	20	3	0	4	16	7	1	6	0	0	53	35	7	0	0	0	2	.444	.528	.778	1.306
21	Padres	16	8/22/2000	SDP	vs	NYM	W 16-1	37	12	6	0	3	15	8	0	7	1	0	45	27	9	0	0	0	0	.324	.444	.730	1.174
22	Padres	16	8/6/1995	SDP	@	COL	W 16-8	43	19	3	1	4	16	4	1	6	0	0	49	36	8	0	1	0	2	.442	.490	.837	1.327
23	Padres	16	4/5/1983	SDP	@	SFG	W 16-13	43	17	5	0	1	15	10	0	5	1	1	54	25	6	0	1	2	0	.395	.500	.581	1.081
24	Padres	16	7/26/1970	SDP	@	PHI	W 16-2	43	16	3	0	4	15	4	2	9	1	0	49	31	7	0	0	0	0	.372	.449	.721	1.170
25	Padres	15	3/21/2024	SDP	@	LAD	W 15-11	43	18	3	1	1	14	6	2	8	1	0	53	26	5	0	2	0	1	.419	.491	.605	1.095