Between the 2005 and 2015 seasons, Felix Hernandez struck out the most batters, with 2,142 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Felix Hernandez F. Hernandez	2,142	334	143	101	.586	334	3.11	25	11	0	2262.1	2,019	783	870	184	630	71	0	16	9,251	126	8.52	2.51	3.40	0.73	23.2	6.8	1.17	.295	3.46	78	3.19	78	8.03	226.6
2	CC Sabathia	1,974	326	160	94	.630	326	3.54	33	10	0	2212.2	2,118	870	963	218	573	74	0	33	9,192	46	8.03	2.33	3.45	0.89	21.5	6.2	1.22	.299	3.92	83	3.47	81	8.61	200.7
3	A.J. Burnett	1,958	333	127	119	.516	331	4.04	14	4	0	2086.2	1,984	936	1,030	209	802	119	1	20	8,946	129	8.45	3.46	2.44	0.90	21.9	9.0	1.34	.303	4.44	98	3.84	93	8.56	71.5
4	Justin Verlander J. Verlander	1,943	318	157	97	.618	318	3.52	21	7	0	2111.1	1,901	825	900	187	642	72	0	22	8,761	67	8.28	2.74	3.03	0.80	22.2	7.3	1.20	.290	3.84	83	3.43	81	8.10	183.2
5	Dan Haren D. Haren	1,938	363	147	121	.549	361	3.70	16	6	1	2301.0	2,228	945	1,038	292	461	60	2	37	9,507	94	7.58	1.80	4.20	1.14	20.4	4.8	1.17	.287	4.06	91	3.74	92	8.71	94
6	Cole Hamels C. Hamels	1,922	307	121	91	.571	306	3.31	15	7	0	2013.2	1,794	741	786	222	515	55	0	40	8,216	39	8.59	2.30	3.73	0.99	23.4	6.3	1.15	.286	3.51	81	3.48	85	8.02	140.5
7	James Shields J. Shields	1,842	319	127	97	.567	318	3.74	22	9	0	2112.2	2,067	878	958	260	533	77	0	16	8,784	81	7.85	2.27	3.46	1.11	21.0	6.1	1.23	.298	4.08	92	3.82	94	8.81	59.4
8	Zack Greinke Z. Greinke	1,787	340	134	82	.620	299	3.30	14	4	1	1949.2	1,829	715	777	169	482	51	8	14	8,013	66	8.25	2.22	3.71	0.78	22.3	6.0	1.19	.301	3.59	81	3.20	79	8.44	183.7
9	Clayton Kershaw C. Kershaw	1,746	244	114	56	.671	242	2.43	21	12	0	1611.0	1,198	435	474	97	466	27	1	26	6,379	62	9.75	2.60	3.75	0.54	27.4	7.3	1.03	.272	2.65	64	2.62	67	6.69	225.7
10	Tim Lincecum T. Lincecum	1,704	269	108	83	.565	261	3.61	10	7	1	1643.2	1,438	660	705	136	646	42	3	33	6,920	104	9.33	3.54	2.64	0.74	24.6	9.3	1.27	.296	3.86	96	3.35	88	7.87	94.2
11	Jake Peavy J. Peavy	1,686	281	114	93	.551	280	3.54	15	6	0	1799.2	1,575	707	738	184	504	56	0	30	7,367	35	8.43	2.52	3.35	0.92	22.9	6.8	1.16	.282	3.69	87	3.49	85	7.88	128.3
12	Jon Lester J. Lester	1,664	285	127	79	.617	284	3.55	12	4	0	1801.0	1,675	711	762	161	592	63	0	4	7,511	47	8.32	2.96	2.81	0.80	22.2	7.9	1.26	.301	3.81	83	3.50	86	8.37	108.8
13	Cliff Lee C. Lee	1,613	284	126	79	.615	280	3.35	29	12	0	1915.0	1,881	712	780	186	355	37	1	9	7,861	32	7.58	1.67	4.54	0.87	20.5	4.5	1.17	.299	3.67	81	3.27	79	8.84	179.9
14	Aaron Harang A. Harang	1,611	327	108	124	.466	323	4.15	14	7	0	2006.1	2,101	925	996	254	595	54	1	47	8,583	65	7.23	2.67	2.71	1.14	18.8	6.9	1.34	.304	4.47	102	4.11	99	9.42	14.9
15	John Lackey J. Lackey	1,601	304	132	94	.584	304	3.78	14	5	0	1970.2	2,000	828	903	197	550	90	0	20	8,346	81	7.31	2.51	2.91	0.90	19.2	6.6	1.29	.305	4.12	89	3.75	91	9.13	82.9
16	Max Scherzer M. Scherzer	1,597	240	105	62	.629	231	3.46	5	4	0	1468.0	1,298	564	612	160	423	49	2	9	6,037	55	9.79	2.59	3.78	0.98	26.5	7.0	1.17	.299	3.75	84	3.29	81	7.96	123.7
17	Ervin Santana E. Santana	1,589	316	126	105	.545	313	4.16	14	7	0	1990.2	1,931	920	987	257	625	88	1	30	8,415	73	7.18	2.83	2.54	1.16	18.9	7.4	1.28	.286	4.46	101	4.25	104	8.73	-35
18	Matt Cain M. Cain	1,547	294	97	99	.495	291	3.47	15	6	0	1872.0	1,589	722	767	177	631	54	1	35	7,734	62	7.44	3.03	2.45	0.85	20.0	8.2	1.19	.265	3.69	88	3.77	96	7.64	37
19	Jered Weaver J. Weaver	1,495	291	138	81	.630	291	3.40	13	7	0	1847.0	1,652	698	732	209	488	47	0	15	7,573	36	7.28	2.38	3.06	1.02	19.7	6.4	1.16	.271	3.57	84	3.82	94	8.05	52.1
20	Josh Beckett J. Beckett	1,460	258	112	80	.583	258	3.98	11	5	0	1620.2	1,521	717	766	197	464	66	0	19	6,771	42	8.11	2.58	3.15	1.09	21.6	6.9	1.22	.289	4.25	92	3.86	94	8.45	51.2
21	Ubaldo Jimenez U. Jimenez	1,456	269	100	94	.515	265	4.01	8	3	0	1585.0	1,438	707	766	137	718	70	0	30	6,808	85	8.27	4.08	2.03	0.78	21.4	10.5	1.36	.294	4.35	95	3.87	92	8.17	59.8
22	Scott Kazmir S. Kazmir	1,433	264	96	87	.525	264	3.92	3	1	0	1520.0	1,430	662	728	165	608	59	0	13	6,511	66	8.48	3.60	2.36	0.98	22.0	9.3	1.34	.298	4.31	96	3.95	95	8.47	35.1
23	Roy Halladay R. Halladay	1,415	251	136	66	.673	250	3.11	52	14	0	1774.2	1,661	613	657	149	311	57	0	19	7,160	28	7.18	1.58	4.55	0.76	19.8	4.3	1.11	.289	3.33	74	3.22	76	8.42	202.4
24	Francisco Liriano F. Liriano	1,389	254	88	79	.527	227	3.97	3	1	1	1350.0	1,200	596	631	120	570	41	8	11	5,724	76	9.26	3.80	2.44	0.80	24.3	10.0	1.31	.300	4.21	99	3.54	89	8.00	67.6
25	David Price D. Price	1,372	218	104	56	.650	213	3.09	14	3	0	1441.2	1,261	495	551	129	371	35	0	11	5,866	29	8.57	2.32	3.70	0.81	23.4	6.3	1.13	.286	3.44	79	3.19	80	7.87	129.1