Nolan Ryan has struck out the most batters in a month, with 87 strikeouts in June 1977.

	NAME	SO	MONTH	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	87	June 1977	7	2	3	.400	7	2.67	3	1	0	57.1	38	17	24	2	35	2	0	2	243	7	13.66	5.49	2.49	0.31	35.8	14.4	1.27	.308	3.77	5.97
2	Nolan Ryan N. Ryan	85	August 1974	7	4	3	.571	7	1.88	6	0	0	62.1	40	13	15	2	24	2	0	1	250	1	12.27	3.47	3.54	0.29	34.0	9.6	1.03	.277	2.17	5.78
3	Rube Waddell R. Waddell	85	July 1902	12	9	1	.900	9	2.26	9	1	0	99.2	81	25	30	4	21	3	2			4	7.68	1.90	4.05	0.36		5.9	1.02	.314	2.71	7.31
4	Nolan Ryan N. Ryan	83	July 1972	8	4	4	.500	8	3.03	5	3	0	62.1	32	21	22	6	28	2	0	0	244	4	11.98	4.04	2.96	0.87	34.0	11.5	0.96	.208	3.18	4.62
5	Rube Waddell R. Waddell	81	August 1904	8	5	3	.625	8	1.85	7	1	0	78.0	56	16	18	1	25	7	0			0	9.35	2.88	3.24	0.12		8.7	1.04	.320	2.08	6.46
6	Rube Waddell R. Waddell	80	August 1905	11	8	1	.889	8		6	4	0	74.1	51		18	2	23	1	3			1	9.69	2.78	3.48	0.24		12.1	1.00	.583	2.18	6.17
7	Bill Bailey B. Bailey	79	September 1914	11	5	4	.556	10	3.08	5	0	0	76.0	64	26	35	0	46	3	0			6	9.36	5.45	1.72	0.00		25.8	1.45	1.280	4.14	7.58
8	Nolan Ryan N. Ryan	76	September 1972	7	4	3	.571	7	1.81	5	0	0	59.2	34	12	16	2	29	1	0	1	241	4	11.46	4.37	2.62	0.30	31.5	12.0	1.06	.241	2.41	5.13
9	Sam McDowell S. McDowell	76	May 1968	7	5	2	.714	7	1.48	5	1	0	61.0	39	10	16	4	21	2	0	1	239	0	11.21	3.10	3.62	0.59	31.8	8.8	0.98	.257	2.36	5.75
10	Sandy Koufax S. Koufax	76	May 1965	7	5	2	.714	7	2.05	4	1	0	61.1	41	14	18	2	12	3	0	0	242	2	11.15	1.76	6.33	0.29	31.4	5.0	0.86	.262	2.64	6.02
11	Chris Sale C. Sale	75	June 2015	6	2	2	.500	6	1.83	0	0	0	44.1	28	9	10	2	8	1	0	0	170	1	15.23	1.62	9.38	0.41	44.1	4.7	0.81	.310	2.03	5.68
12	Nolan Ryan N. Ryan	75	August 1973	8	4	3	.571	7	3.22	4	1	0	58.2	43	21	23	3	29	2	1	1	251	3	11.51	4.45	2.59	0.46	29.9	11.6	1.23	.282	3.53	6.60
13	Gerrit Cole G. Cole	74	September 2019	6	5	0	1.000	6	1.07	0	0	0	42.0	20	5	6	4	7	1	0	0	152	2	15.86	1.50	10.57	0.86	48.7	4.6	0.64	.242	1.29	4.29
14	Ed Walsh E. Walsh	74	September 1908	13	9	4	.692	12		11	6	0	107.0	70		13	1	12	2	1		396	2	6.22	1.01	6.17	0.08	18.7	3.0	0.77	.225	1.09	5.89
15	Frank Tanana F. Tanana	73	June 1975	7	4	1	.800	7	3.53	3	0	0	58.2	55	23	23	6	14	4	0	2	242	4	11.20	2.15	5.21	0.92	30.2	5.8	1.18	.338	3.53	8.44
16	Sandy Koufax S. Koufax	73	August 1965	8	4	2	.667	7	2.55	5	1	1	60.0	38	17	18	5	14	0	1	3	233	4	10.95	2.10	5.21	0.75	31.3	6.0	0.87	.234	2.70	5.70
17	Sandy Koufax S. Koufax	73	June 1962	8	4	2	.667	7	1.23	4	2	1	58.1	24	8	10	2	16	0	1	1	214	1	11.26	2.47	4.56	0.31	34.1	7.5	0.69	.179	1.54	3.70
18	Rube Waddell R. Waddell	73	July 1903	9	5	3	.625	9	2.96	7	2	0	73.0	67	24	27	1	26	2	0			5	9.00	3.21	2.81	0.12		10.3	1.27	.440	3.33	8.26
19	Pedro Martinez P. Martinez	72	June 1997	6	2	2	.500	6	1.78	4	1	0	50.2	29	10	10	3	15	0	0	3	198	0	12.79	2.66	4.80	0.53	36.4	7.6	0.87	.241	1.78	5.15
20	Sam McDowell S. McDowell	71	May 1970	7	4	1	.800	7	2.44	4	1	0	59.0	40	16	17	5	21	0	0	2	234	2	10.83	3.20	3.38	0.76	30.3	9.0	1.03	.255	2.59	6.10
21	Tom Seaver T. Seaver	71	May 1970	7	3	4	.429	7	2.58	4	1	0	59.1	39	17	17	7	20	1	0	3	234	1	10.77	3.03	3.55	1.06	30.3	8.5	0.99	.237	2.58	5.92
22	Sam McDowell S. McDowell	71	August 1965	9	4	3	.571	8	2.73	4	0	1	59.1	45	18	23	1	25	4	1	2	247	2	10.77	3.79	2.84	0.15	28.7	10.1	1.18	.301	3.49	6.83
23	Christy Mathewson C. Mathewson	71	August 1903	10	9	1	.900	10		8	0	0	83.1	85		35	1	19	3	0		358	4	7.67	2.05	3.74	0.11	19.8	5.3	1.25	.318	3.78	9.18
24	Randy Johnson R. Johnson	70	August 2002	6	4	1	.800	6	2.14	2	2	0	46.1	29	11	13	3	14	4	0	1	184	1	13.60	2.72	5.00	0.58	38.0	7.6	0.93	.280	2.53	5.63
25	Pedro Martinez P. Martinez	70	September 1999	5	4	0	1.000	5	0.88	2	1	0	41.0	20	4	5	1	6	3	0	0	150	1	15.37	1.32	11.67	0.22	46.7	4.0	0.63	.271	1.10	4.39