Early Wynn won the most games in 1959, with 22 wins.

	NAME	W	SEASON	TM	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Early Wynn E. Wynn	22	1959	CWS	10	.688	37	37	3.17	179	14	5	0	255.2	202	90	106	20	119	9	0	5	1,076	5	6.30	4.19	1.50	0.70	16.6	11.1	1.26	.243	3.73	84	3.66	95	7.11	5.5
2	Lew Burdette L. Burdette	21	1959	MIL	15	.583	41	39	4.07	105	20	4	1	289.2	312	131	144	38	38	1	2	3	1,193	2	3.26	1.18	2.76	1.18	8.8	3.2	1.21	.271	4.47	113	3.93	112	9.69	-16.1
3	Sam Jones S. Jones	21	1959	SFG	15	.583	50	35	2.83	209	16	4	5	270.2	232	85	99	18	109	8	12	6	1,148	5	6.95	3.62	1.92	0.60	18.2	9.5	1.26	.266	3.29	73	3.16	83	7.71	19
4	Warren Spahn W. Spahn	21	1959	MIL	15	.583	40	36	2.96	143	21	4	0	292.0	282	96	106	21	70	1	3	9	1,203	2	4.41	2.16	2.04	0.65	11.9	5.8	1.21	.270	3.27	82	3.23	92	8.69	8.7
5	Johnny Antonelli J. Antonelli	19	1959	SFG	10	.655	40	38	3.10	165	17	4	1	282.0	247	97	107	29	76	3	1	6	1,150	1	5.27	2.43	2.17	0.93	14.3	6.6	1.15	.249	3.41	80	3.55	94	7.88	7.4
6	Cal McLish C. McLish	19	1959	CLE	8	.704	35	32	3.63	113	13	0	1	235.1	253	95	110	26	72	5	1	6	1,021	4	4.32	2.75	1.57	0.99	11.1	7.1	1.38	.282	4.21	96	4.00	104	9.68	-4
7	Roy Face R. Face	18	1959	PIT	1	.947	57	0	2.70	69	0	0	10	93.1	91	28	29	5	25	1	47	8	380	4	6.65	2.41	2.76	0.48	18.2	6.6	1.24	.307	2.80	70	2.60	69	8.78	12.5
8	Vern Law V. Law	18	1959	PIT	9	.667	34	33	2.98	110	20	2	1	266.0	245	88	91	25	53	2	1	11	1,080	5	3.72	1.79	2.08	0.85	10.2	4.9	1.12	.247	3.08	77	3.56	94	8.29	6.7
9	Bob Shaw B. Shaw	18	1959	CWS	6	.750	47	26	2.69	89	8	3	3	230.2	217	69	72	15	54	6	12	5	949	3	3.47	2.11	1.65	0.59	9.4	5.7	1.17	.257	2.81	71	3.40	88	8.47	11.9
10	Jim Bunning J. Bunning	17	1959	DET	13	.567	40	35	3.89	201	14	1	1	249.2	220	108	111	37	75	11	4	0	1,037	1	7.25	2.70	2.68	1.33	19.4	7.2	1.18	.257	4.00	98	3.89	96	7.93	4.9
11	Don Drysdale D. Drysdale	17	1959	LAD	13	.567	44	36	3.46	242	15	4	2	270.2	237	104	113	26	93	18	7	9	1,142	4	8.05	3.09	2.60	0.86	21.2	8.1	1.22	.277	3.76	83	3.23	80	7.88	24.4
12	Frank Lary F. Lary	17	1959	DET	10	.630	32	32	3.55	137	11	3	0	223.0	225	88	109	23	46	11	0	4	931	2	5.53	1.86	2.98	0.93	14.7	4.9	1.22	.283	4.40	89	3.42	84	9.08	15.7
13	Don Mossi D. Mossi	17	1959	DET	9	.654	34	30	3.36	125	15	3	0	228.0	210	85	92	20	49	3	2	0	927	2	4.93	1.93	2.55	0.79	13.5	5.3	1.14	.260	3.63	84	3.27	81	8.29	19.7
14	Camilo Pascual C. Pascual	17	1959	WSH	10	.630	32	30	2.64	185	17	6	0	238.2	202	70	80	10	69	3	1	7	984	5	6.98	2.60	2.68	0.38	18.8	7.0	1.14	.268	3.02	67	2.44	61	7.62	41.3
15	Gary Bell G. Bell	16	1959	CLE	11	.593	44	28	4.04	136	12	1	5	234.0	208	105	107	28	105	5	11	4	1,005	8	5.23	4.04	1.30	1.08	13.5	10.4	1.34	.246	4.12	107	4.35	113	8.00	-13.1
16	Bud Daley B. Daley	16	1959	KCA	13	.552	39	29	3.16	125	12	2	1	216.1	212	76	90	24	62	11	5	2	911	7	5.20	2.58	2.02	1.00	13.7	6.8	1.27	.273	3.74	80	3.84	95	8.82	5.4
17	Whitey Ford W. Ford	16	1959	NYY	10	.615	35	29	3.04	114	9	2	2	204.0	194	69	82	13	89	1	4	5	877	5	5.03	3.93	1.28	0.57	13.0	10.1	1.39	.274	3.62	83	3.58	96	8.56	3.3
18	Glen Hobbie G. Hobbie	16	1959	CHC	13	.552	46	33	3.69	138	10	3	0	234.0	204	96	105	15	106	6	3	1	991	9	5.31	4.08	1.30	0.58	13.9	10.7	1.32	.260	4.04	94	3.63	94	7.85	6.1
19	Bob Buhl B. Buhl	15	1959	MIL	9	.625	31	25	2.86	105	12	4	0	198.0	181	63	76	19	74	2	2	3	832	4	4.77	3.36	1.42	0.86	12.6	8.9	1.29	.256	3.45	80	3.88	110	8.23	-9.9
20	Milt Pappas M. Pappas	15	1959	BAL	9	.625	33	27	3.27	120	15	4	3	209.1	175	76	82	8	75	4	4	2	858	14	5.16	3.22	1.60	0.34	14.0	8.7	1.19	.257	3.53	89	3.03	81	7.52	16.9
21	Robin Roberts R. Roberts	15	1959	PHI	17	.469	35	35	4.27	137	19	2	0	257.1	267	122	137	34	35	5	0	4	1,075	1	4.79	1.22	3.91	1.19	12.7	3.3	1.17	.270	4.79	108	3.66	95	9.34	5.9
22	Jack Sanford J. Sanford	15	1959	SFG	12	.556	36	31	3.16	132	10	0	1	222.1	198	78	90	22	70	7	2	4	933	7	5.34	2.83	1.89	0.89	14.1	7.5	1.21	.251	3.64	82	3.68	97	8.01	2.5
23	Hoyt Wilhelm H. Wilhelm	15	1959	BAL	11	.577	32	27	2.19	139	13	3	0	226.0	178	55	64	13	77	10	2	3	902	5	5.54	3.07	1.81	0.52	15.4	8.5	1.13	.249	2.55	60	3.22	86	7.09	13.3
24	Paul Foytack P. Foytack	14	1959	DET	14	.500	39	37	4.64	110	11	2	1	240.1	239	124	137	34	64	2	1	3	1,000	6	4.12	2.40	1.72	1.27	11.0	6.4	1.26	.259	5.13	117	4.29	106	8.95	-5.6
25	Larry Jackson L. Jackson	14	1959	STL	13	.519	40	37	3.30	145	12	3	0	256.0	271	94	103	13	64	4	2	3	1,081	7	5.10	2.25	2.27	0.46	13.4	5.9	1.31	.302	3.62	79	2.87	70	9.53	33.9