Between the 1910 and 1928 seasons, Grover Alexander pitched the most innings in the NL, with 5036.1 innings.

	NAME	IP	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Grover Alexander G. Alexander	5036.1	665	364	197	.649	578	2.50	2,159	428	90	32	4,679	1,397	1,763	150	922	69	76	20,222	36	3.86	1.65	2.34	0.27	10.7	4.6	1.11	.268	3.15	72	2.83	81	8.36	355.7
2	Eppa Rixey E. Rixey	3797.0	562	232	210	.525	469	3.00	1,230	259	34	13	3,822	1,265	1,612	68	917	62	66	15,727	87	2.92	2.17	1.34	0.16	7.8	5.8	1.25	.279	3.82	86	3.15	89	9.06	156.1
3	Wilbur Cooper W. Cooper	3466.1	509	216	174	.554	403	2.86	1,250	279	35	14	3,388	1,102	1,388	103	844	97	83	14,299	44	3.25	2.19	1.48	0.27	8.7	5.9	1.22	.274	3.60	86	3.17	94	8.80	74
4	Burleigh Grimes B. Grimes	3256.0	448	207	162	.561	380	3.41	1,243	260	27	10	3,358	1,234	1,557	105	988	75	58	13,910	75	3.44	2.73	1.26	0.29	8.9	7.1	1.33	.283	4.30	94	3.47	95	9.28	66.1
5	Lee Meadows L. Meadows	3160.0	489	188	180	.511	406	3.37	1,063	219	25	7	3,278	1,184	1,490	85	955	90	59	13,366	60	3.03	2.72	1.11	0.24	8.0	7.1	1.34	.286	4.24	96	3.41	97	9.34	68.6
6	Rube Marquard R. Marquard	3128.2	506	196	163	.546	385	3.10	1,482	189	30	19	3,072	1,078	1,357	105	783	29	78	12,912	72	4.26	2.25	1.89	0.30	11.5	6.1	1.23	.282	3.90	97	2.92	90	8.84	100.9
7	Babe Adams B. Adams	2839.1	452	182	134	.576	338	2.78	960	197	41	14	2,704	878	1,075	66	402	41	78	11,347	24	3.04	1.27	2.39	0.21	8.5	3.5	1.09	.267	3.41	86	2.76	84	8.57	167.4
8	Bill Doak B. Doak	2773.2	450	168	155	.520	367	2.95	1,011	162	34	16	2,659	908	1,169	70	846	65	62	11,533	38	3.28	2.75	1.20	0.23	8.8	7.3	1.26	.271	3.79	93	3.22	100	8.63	-4
9	Art Nehf A. Nehf	2587.0	419	176	115	.605	306	3.09	817	177	27	13	2,567	889	1,079	96	601	38	79	10,654	33	2.84	2.09	1.36	0.33	7.7	5.6	1.22	.271	3.75	93	3.32	98	8.93	4.1
10	Jesse Barnes J. Barnes	2569.2	422	152	150	.503	312	3.22	653	180	26	14	2,686	918	1,150	89	515	25	78	10,676	22	2.29	1.80	1.27	0.31	6.1	4.8	1.25	.276	4.03	95	3.34	98	9.41	3.1
11	Rube Benton R. Benton	2517.1	437	150	144	.510	311	3.09	950	145	23	21	2,472	863	1,115	52	712	95	82	10,539	66	3.40	2.55	1.33	0.19	9.0	6.8	1.26	.277	3.99	100	3.11	99	8.84	14.1
12	Dolf Luque D. Luque	2506.1	367	149	137	.521	301	3.00	931	176	23	11	2,417	835	1,043	71	708	22	52	10,388	39	3.34	2.54	1.31	0.25	9.0	6.8	1.25	.271	3.75	83	3.43	94	8.68	63.4
13	Slim Sallee S. Sallee	2474.0	419	161	124	.565	266	2.55	742	170	23	36	2,362	700	920	64	478	35	111	10,002	9	2.70	1.74	1.55	0.23	7.4	4.8	1.15	.265	3.35	86	2.89	96	8.59	30.1
14	Jeff Pfeffer J. Pfeffer	2397.1	345	158	112	.585	279	2.76	832	193	28	10	2,309	734	910	67	588	105	52	9,927	34	3.12	2.21	1.41	0.25	8.4	5.9	1.21	.269	3.42	86	3.13	98	8.67	16.8
15	Jimmy Ring J. Ring	2357.1	389	118	149	.442	294	4.13	833	154	9	11	2,551	1,082	1,329	105	953	30	56	10,330	88	3.18	3.64	0.87	0.40	8.1	9.2	1.49	.291	5.07	106	3.99	102	9.74	-1.3
16	Lefty Tyler L. Tyler	2230.0	323	127	116	.523	267	2.95	1,003	181	30	7	1,990	730	947	51	829	67	45	9,222	55	4.05	3.35	1.21	0.21	10.9	9.0	1.26	.267	3.82	96	3.11	101	8.03	-2.7
17	Hippo Vaughn H. Vaughn	2216.1	305	151	105	.590	270	2.33	1,138	177	35	4	1,971	575	789	35	621	63	31	9,097	41	4.62	2.52	1.83	0.14	12.5	6.8	1.17	.267	3.20	79	2.56	86	8.00	96.3
18	Fred Toney F. Toney	2206.0	336	139	102	.577	271	2.69	718	158	28	12	2,037	659	835	58	583	46	49	8,988	37	2.93	2.38	1.23	0.24	8.0	6.5	1.19	.261	3.41	87	3.12	101	8.31	-14.6
19	Bill Sherdel B. Sherdel	2185.1	416	140	114	.551	214	3.41	680	133	10	25	2,350	827	999	108	523	48	142	9,254	20	2.80	2.15	1.30	0.44	7.3	5.7	1.31	.284	4.11	93	3.69	98	9.68	17
20	Jesse Haines J. Haines	2153.2	319	140	109	.562	268	3.44	685	157	20	5	2,265	822	1,010	101	572	45	32	9,095	31	2.86	2.39	1.20	0.42	7.5	6.3	1.32	.281	4.22	90	3.80	98	9.47	17
21	Dick Rudolph D. Rudolph	2049.0	279	121	109	.526	240	2.66	786	172	27	8	1,971	605	778	35	402	27	36	8,286	39	3.45	1.77	1.96	0.15	9.5	4.9	1.16	.275	3.42	94	2.50	88	8.66	76.7
22	Red Ames R. Ames	2011.1	359	111	117	.487	232	2.73	858	118	18	29	1,914	611	838	30	574	40	90	8,274	78	3.84	2.57	1.49	0.13	10.4	6.9	1.24	.278	3.75	94	2.71	92	8.56	53.9
23	Bob Harmon B. Harmon	1895.0	300	101	122	.453	223	3.31	586	133	15	12	1,811	696	872	38	697	34	58	7,871	32	2.78	3.31	0.84	0.18	7.4	8.9	1.32	.272	4.14	109	3.33	108	8.60	-57.7
24	Larry Cheney L. Cheney	1881.1	313	116	100	.537	225	2.70	926	132	20	19	1,605	564	784	36	733	59	63	7,865	119	4.43	3.51	1.26	0.17	11.8	9.3	1.24	.257	3.75	92	3.00	101	7.68	-5.6
25	Hal Carlson H. Carlson	1838.2	338	99	113	.467	217	3.87	541	112	15	18	2,057	790	911	80	453	34	87	7,795	17	2.65	2.22	1.19	0.39	6.9	5.8	1.37	.296	4.46	101	3.64	95	10.07	48