Between the 1970 and 1979 seasons, Nolan Ryan struck out the most batters, with 2,678 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Nolan Ryan N. Ryan	2,678	348	155	146	.515	333	3.14	164	42	2	2465.0	1,731	860	984	133	1,515	75	8	34	10,453	116	9.78	5.53	1.77	0.49	25.6	14.5	1.32	.264	3.59	89	3.05	85	6.32	150.5
2	Tom Seaver T. Seaver	2,304	348	178	101	.638	345	2.61	147	40	0	2652.1	2,105	768	843	190	741	28	2	65	10,607	64	7.82	2.51	3.11	0.64	21.7	7.0	1.07	.261	2.86	73	2.64	74	7.14	272
3	Steve Carlton S. Carlton	2,097	368	178	126	.586	366	3.18	165	32	0	2747.0	2,413	971	1,103	238	960	31	0	87	11,361	81	6.87	3.15	2.18	0.78	18.5	8.4	1.23	.271	3.61	85	3.26	89	7.91	125.5
4	Bert Blyleven B. Blyleven	2,082	353	148	128	.536	350	2.88	145	39	0	2624.2	2,335	841	949	186	711	70	2	43	10,722	61	7.14	2.44	2.93	0.64	19.4	6.6	1.16	.280	3.25	78	2.80	76	8.01	260.7
5	Gaylord Perry G. Perry	1,907	369	184	133	.580	368	2.92	197	36	1	2905.0	2,559	942	1,088	207	758	51	1	75	11,759	68	5.91	2.35	2.52	0.64	16.2	6.4	1.14	.266	3.37	80	3.02	83	7.93	199.6
6	Phil Niekro P. Niekro	1,866	406	164	151	.521	376	3.26	160	25	8	2881.0	2,642	1,045	1,228	259	920	76	19	53	12,043	116	5.83	2.87	2.03	0.81	15.5	7.6	1.24	.267	3.84	83	3.50	90	8.25	120.6
7	Fergie Jenkins F. Jenkins	1,841	360	178	130	.578	354	3.38	184	33	0	2706.2	2,507	1,015	1,128	301	518	51	5	55	11,009	34	6.12	1.72	3.55	1.00	16.7	4.7	1.12	.266	3.75	86	3.29	86	8.34	158.8
8	Don Sutton D. Sutton	1,767	352	166	110	.601	349	3.07	117	39	2	2557.1	2,174	871	975	214	660	45	3	45	10,403	63	6.22	2.32	2.68	0.75	17.0	6.3	1.11	.254	3.43	87	3.11	88	7.65	121.3
9	Vida Blue V. Blue	1,600	330	155	109	.587	327	3.07	124	32	1	2398.2	2,080	819	927	161	780	19	1	42	9,827	69	6.00	2.93	2.05	0.60	16.3	7.9	1.19	.264	3.48	88	3.12	87	7.80	125.1
10	Jerry Koosman J. Koosman	1,587	337	124	127	.494	313	3.30	85	15	5	2281.1	2,119	837	947	173	747	40	13	74	9,498	53	6.26	2.95	2.12	0.68	16.7	7.9	1.26	.280	3.74	92	3.22	89	8.36	97.6
11	Jim Palmer J. Palmer	1,559	355	186	103	.644	352	2.58	175	44	2	2745.0	2,275	787	883	184	861	26	3	31	11,105	55	5.11	2.82	1.81	0.60	14.0	7.8	1.14	.247	2.90	73	3.28	90	7.46	110.6
12	Mickey Lolich M. Lolich	1,496	319	115	117	.496	277	3.43	133	20	1	2110.0	2,048	803	897	202	581	32	15	40	8,765	71	6.38	2.48	2.57	0.86	17.1	6.6	1.25	.286	3.83	94	3.23	87	8.74	107.8
13	J.R. Richard	1,374	221	97	67	.591	204	3.24	72	15	0	1492.1	1,162	538	594	71	730	17	3	14	6,236	90	8.29	4.40	1.88	0.43	22.0	11.7	1.27	.270	3.58	95	2.92	84	7.01	94.8
14	Andy Messersmith A. Messersmith	1,340	276	110	86	.561	257	2.93	86	24	9	1899.0	1,506	619	710	154	696	34	16	33	7,791	51	6.35	3.30	1.93	0.73	17.2	8.9	1.16	.243	3.36	84	3.36	94	7.14	43.9
15	Joe Coleman J. Coleman	1,319	380	107	97	.525	246	3.76	64	12	6	1937.2	1,813	810	919	183	795	63	68	51	8,277	89	6.13	3.69	1.66	0.85	15.9	9.6	1.35	.275	4.27	102	3.74	100	8.42	-0.8
16	Catfish Hunter C. Hunter	1,309	329	169	102	.624	327	3.17	140	30	0	2399.0	2,047	846	936	257	606	34	2	31	9,702	33	4.91	2.27	2.16	0.96	13.5	6.2	1.11	.239	3.51	90	3.67	102	7.68	-26.2
17	Rudy May R. May	1,238	338	110	107	.507	271	3.46	74	22	3	1870.1	1,649	720	825	143	708	31	23	42	7,807	36	5.96	3.41	1.75	0.69	15.9	9.1	1.26	.265	3.97	100	3.43	97	7.93	20.1
18	Luis Tiant L. Tiant	1,229	322	142	92	.607	285	3.42	120	28	3	2063.0	1,904	783	839	204	595	28	18	22	8,498	12	5.36	2.60	2.07	0.89	14.5	7.0	1.21	.264	3.66	86	3.59	92	8.31	68.8
19	Jon Matlack J. Matlack	1,215	251	102	98	.510	245	2.97	85	28	1	1803.0	1,662	595	693	115	485	20	4	62	7,405	51	6.06	2.42	2.51	0.57	16.4	6.5	1.19	.278	3.46	84	2.89	81	8.30	133.8
20	Fred Norman F. Norman	1,208	340	100	94	.515	253	3.54	54	15	4	1794.2	1,642	705	777	170	744	19	28	69	7,636	80	6.06	3.73	1.62	0.85	15.8	9.7	1.33	.268	3.90	99	3.74	105	8.23	-39.1
21	Jerry Reuss J. Reuss	1,141	323	114	108	.514	287	3.79	83	22	6	1967.0	2,000	828	942	121	742	34	18	66	8,486	73	5.22	3.40	1.54	0.55	13.4	8.7	1.39	.291	4.31	105	3.40	95	9.15	41.9
22	Wilbur Wood W. Wood	1,138	363	136	123	.525	276	3.31	113	24	22	2150.1	2,087	792	923	170	570	50	68	31	8,931	49	4.76	2.39	2.00	0.71	12.7	6.4	1.24	.274	3.86	89	3.37	91	8.73	73.8
23	Rick Reuschel R. Reuschel	1,122	284	114	101	.530	274	3.43	57	17	3	1834.1	1,856	699	790	115	508	48	7	64	7,734	56	5.50	2.49	2.21	0.56	14.5	6.6	1.29	.293	3.88	87	3.11	81	9.11	149.6
24	Frank Tanana F. Tanana	1,120	193	91	66	.580	187	2.93	85	24	0	1411.1	1,238	459	507	128	377	47	3	24	5,775	38	7.14	2.40	2.97	0.82	19.4	6.5	1.14	.271	3.23	82	3.11	85	7.89	88.7
25	Steve Renko S. Renko	1,112	323	94	109	.463	272	3.95	47	9	4	1846.0	1,764	810	912	184	775	17	20	74	7,926	60	5.42	3.78	1.43	0.90	14.0	9.8	1.38	.271	4.45	103	3.96	106	8.60	-37