Rickey Henderson has the most career walks when leading off a game, with 394 walks.

	NAME	BB	G	AB	H	2B	3B	HR	RBI	HBP	SO	PA	TB	XBH	SH	SF	IBB	AVG	OBP	SLG	OPS
1	Rickey Henderson R. Henderson	394	2,875	2,462	680	117	17	81	81	19	408	2,875	1,074	215	0	0	0	.276	.380	.436	.816
2	Kenny Lofton K. Lofton	211	1,705	1,487	448	68	22	29	29	7	227	1,705	647	119	0	0	0	.301	.391	.435	.826
3	Brett Butler B. Butler	202	1,844	1,637	473	55	22	8	8	5	174	1,844	596	85	0	0	0	.289	.369	.364	.733
4	Tony Phillips T. Phillips	190	1,381	1,187	317	56	7	30	30	4	249	1,381	477	93	0	0	0	.267	.370	.402	.772
5	Johnny Damon J. Damon	147	1,575	1,422	388	62	13	27	27	6	201	1,575	557	102	0	0	0	.273	.343	.392	.735
6	Chuck Knoblauch C. Knoblauch	139	1,289	1,127	309	51	9	31	31	23	152	1,289	471	91	0	0	0	.274	.365	.418	.783
7	Willie Randolph W. Randolph	138	877	738	205	27	6	4	4	1	69	877	256	37	0	0	0	.278	.392	.347	.739
8	Tim Raines T. Raines	137	1,398	1,252	361	60	26	16	16	9	146	1,398	521	102	0	0	0	.288	.363	.416	.779
9	Lenny Dykstra L. Dykstra	136	1,095	951	236	54	13	20	20	8	132	1,095	376	87	0	0	0	.248	.347	.395	.742
10	Brady Anderson B. Anderson	132	1,294	1,139	298	63	10	44	44	23	196	1,294	513	117	0	0	0	.262	.350	.450	.800
11	Eric Young E. Young	128	1,242	1,097	296	59	14	20	20	17	112	1,242	443	93	0	0	0	.270	.355	.404	.759
12	Otis Nixon O. Nixon	121	1,093	971	268	28	3	3	3	1	139	1,093	311	34	0	0	0	.276	.357	.320	.677
13	Davey Lopes D. Lopes	119	1,058	934	243	40	7	28	28	5	151	1,058	381	75	0	0	0	.260	.347	.408	.755
14	Vince Coleman V. Coleman	118	1,275	1,149	303	42	20	5	5	8	232	1,275	400	67	0	0	0	.264	.336	.348	.685
15	Craig Biggio C. Biggio	114	1,560	1,407	400	106	9	53	53	39	233	1,560	683	168	0	0	0	.284	.354	.485	.840
16	Denard Span D. Span	112	1,157	1,042	257	57	8	15	15	3	157	1,157	375	80	0	0	0	.247	.322	.360	.681
17	Paul Molitor P. Molitor	111	1,570	1,451	423	78	19	33	33	8	188	1,570	638	130	0	0	0	.292	.345	.440	.785
18	Wade Boggs W. Boggs	107	926	818	247	49	2	5	5	1	62	926	315	56	0	0	0	.302	.383	.385	.768
19	Ron LeFlore R. LeFlore	98	1,039	940	248	37	7	6	6	1	223	1,039	317	50	0	0	0	.264	.334	.337	.671
20	Al Bumbry A. Bumbry	98	1,069	970	279	43	11	12	12	1	164	1,069	380	66	0	0	0	.288	.354	.392	.745
21	Matt Carpenter M. Carpenter	97	767	666	186	45	6	25	25	4	157	767	318	76	0	0	0	.279	.374	.477	.852
22	Brian Roberts B. Roberts	96	1,133	1,037	277	74	3	13	13	0	138	1,133	396	90	0	0	0	.267	.329	.382	.711
23	Curtis Granderson C. Granderson	89	986	890	223	39	12	47	47	7	220	986	427	98	0	0	0	.251	.324	.480	.803
24	Lou Whitaker L. Whitaker	89	911	819	238	42	8	23	23	3	103	911	365	73	0	0	0	.291	.362	.446	.808
25	George Springer G. Springer	88	1,048	943	270	38	4	63	63	14	219	1,048	505	105	0	0	0	.286	.356	.536	.892