The Boston Red Sox have a record of 46-50 on April 21 all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Americans	4/21/1905	0-1	BSA	vs	PHA	L 4-5	.000	31	4	7	0	0	0	2	5	0	9	2		38	7	0	2				.226	.333	.226	.559
2	Americans	4/21/1906	0-1	BSA	@	WSH	L 3-4	.000	36	3	5	1	1	0	3	3	0		2		40	8	2	1				.139	.205	.222	.427
3	Red Sox	4/21/1908	0-1	BOS	vs	PHA	L 0-4	.000	33	0	6	0	0	0	0	0	0	5	1		34	6	0	1				.182	.182	.182	.364
4	Red Sox	4/21/1909	1-0	BOS	vs	PHA	W 6-2	1.000	32	6	7	0	1	0	3	4	0	4	5		37	9	1	1				.219	.306	.281	.587
5	Red Sox	4/21/1910	1-0	BSA	vs	WSH	W 10-3	1.000	31	10	10	0	1	3	10	4	1		4		38	21	4	2				.323	.417	.677	1.094
6	Red Sox	4/21/1911	1-0	BSA	vs	PHA	W 13-4	1.000	38	13	17	6	0	1	12	3	0	1	1		44	26	7	3				.447	.488	.684	1.172
7	Red Sox	4/21/1913	0-1	BSA	@	PHA	L 4-6	.000	30	4	8	1	0	0	3	9	1	7	2		43	9	1	3				.267	.450	.300	.750
8	Red Sox	4/21/1914		BSA	vs	PHA	N 1-1		43	1	6	0	1	0	0	4	0	3	0		48	8	1	1				.140	.213	.186	.399
9	Red Sox	4/21/1915	0-1	BSA	@	WSH	L 3-11	.000	32	3	8	2	1	1	3	4	0	3	0		36	15	4	0				.250	.333	.469	.802
10	Red Sox	4/21/1916	0-1	BSA	@	PHA	L 1-3	.000	29	1	4	0	0	0	1	3	0	2	0		33	4	0	1				.138	.219	.138	.357
11	Red Sox	4/21/1917	1-0	BSA	vs	NYY	W 6-4	1.000	31	6	11	2	1	0	6	1	0	1	0		35	15	3	3				.355	.375	.484	.859
12	Red Sox	4/21/1921	1-0	BSA	vs	WSH	W 1-0	1.000	29	1	7	1	0	0	1	2	0	2	0	0	32	8	1	1				.241	.290	.276	.566
13	Red Sox	4/21/1923	0-1	BSA	@	NYY	L 6-7	.000	37	6	13	4	0	1	6	1	1	0	0	1	41	20	5	2				.351	.385	.541	.925
14	Red Sox	4/21/1924	0-1	BSA	vs	PHA	L 0-4	.000	30	0	5	1	0	0	0	3	0	0	0	0	33	6	1	0				.167	.242	.200	.442
15	Red Sox	4/21/1925	0-1	BSA	@	NYY	L 1-5	.000	33	1	6	0	0	1	1	1	0	8	0	0	34	9	1	0				.182	.206	.273	.479
16	Red Sox	4/21/1926	0-1	BSA	@	NYY	L 5-8	.000	35	5	9	3	1	0	5	2	0	4	1	0	39	14	4	2				.257	.297	.400	.697
17	Red Sox	4/21/1927	0-1	BSA	vs	WSH	L 4-7	.000	30	4	4	0	0	1	4	7	0	3	0	0	37	7	1	0				.133	.297	.233	.531
18	Red Sox	4/21/1931	0-1	BSA	@	WSH	L 3-12	.000	36	3	7	3	0	0	3	4	0	4	0	0	40	10	3	0				.194	.275	.278	.553
19	Red Sox	4/21/1932	1-0	BSA	@	WSH	W 1-0	1.000	31	1	4	1	0	0	1	0	0	4	0	0	32	5	1	1				.129	.129	.161	.290
20	Red Sox	4/21/1933	0-1	BSA	vs	NYY	L 5-7	.000	35	5	8	3	0	0	3	2	0	7	0	0	37	11	3	0				.229	.270	.314	.585
21	Red Sox	4/21/1934	1-0	BSA	vs	NYY	W 9-6	1.000	34	9	9	4	0	0	9	6	0	6	2	0	40	13	4	0				.265	.375	.382	.757
22	Red Sox	4/21/1936	1-0	BSA	vs	WSH	W 8-1	1.000	25	8	9	1	0	1	7	7	0	0	1	0	34	13	2	2				.360	.500	.520	1.020
23	Red Sox	4/21/1938	1-0	BSA	vs	NYY	W 3-2	1.000	24	3	3	0	1	0	3	10	1	4	0	1	36	5	1	1				.125	.400	.208	.608
24	Red Sox	4/21/1939	1-0	BSA	vs	PHA	W 9-2	1.000	34	9	8	3	0	0	8	7	1	3	0	0	42	11	3	0			0	.235	.381	.324	.704
25	Red Sox	4/21/1941	0-1	BSA	@	WSH	L 5-6	.000	40	5	11	2	2	0	5	2	0	2	1	0	42	17	4	0			0	.275	.310	.425	.735
	Total		46-50					.479	3,286	450	862	164	18	76	421	400	20		62	17	3,771	1,290	258	50	15	15	73	.262	.345	.393	.737