The Detroit Tigers launched their most homers in a game against left-handed pitchers 4 times, with 5 home runs.

Interpreted as:

tigers with most homers in a regular-season game vs lefty

	TEAM	HR	DATE	TM		OPP	VS. HAND	AB	H	2B	3B	RBI	BB	HBP	SO	PA	TB	XBH	SH	SF	IBB	AVG	OBP	SLG	OPS
1	Tigers	5	8/8/2020	DET	@	PIT	LHP	33	15	4	0	9	1	0	8	34	34	9	0	0	0	.455	.471	1.030	1.501
2	Tigers	5	8/19/2015	DET	@	CHC	LHP	41	18	6	1	13	3	0	10	44	41	12	0	0	0	.439	.477	1.000	1.477
3	Tigers	5	7/7/1988	DET	vs	OAK	LHP	15	7	1	0	8	1	0	0	16	23	6	0	0	0	.467	.500	1.533	2.033
4	Tigers	5	9/17/1985	DET	vs	NYY	LHP	35	11	0	0	9	4	0	3	39	26	5	0	0	0	.314	.385	.743	1.127
5	Tigers	4	5/1/2025	DET	@	LAA	LHP	33	11	0	0	10	3	1	7	37	23	4	0	0	0	.333	.405	.697	1.102
6	Tigers	4	6/29/2011	DET	vs	NYM	LHP	23	7	2	0	7	0	0	6	23	21	6	0	0	0	.304	.304	.913	1.217
7	Tigers	4	9/25/2008	DET	vs	TBR	LHP	20	6	0	0	4	2	0	8	22	18	4	0	0	0	.300	.364	.900	1.264
8	Tigers	4	9/8/2008	DET	vs	OAK	LHP	27	11	2	2	13	2	3	4	33	29	8	0	1	0	.407	.485	1.074	1.559
9	Tigers	4	8/9/2008	DET	vs	OAK	LHP	33	13	2	0	10	2	0	2	36	27	6	1	0	1	.394	.429	.818	1.247
10	Tigers	4	9/24/2005	DET	vs	SEA	LHP	30	7	0	0	5	3	0	3	33	19	4	0	0	0	.233	.303	.633	.936
11	Tigers	4	8/27/2003	DET	@	CLE	LHP	21	7	0	0	6	0	1	5	22	19	4	0	0	0	.333	.364	.905	1.268
12	Tigers	4	6/17/1993	DET	vs	CLE	LHP	28	9	1	0	6	3	0	4	31	22	5	0	0	0	.321	.387	.786	1.173
13	Tigers	4	6/6/1990	DET	@	CLE	LHP	21	6	1	0	6	2	0	4	23	19	5	0	0	0	.286	.348	.905	1.253
14	Tigers	4	5/6/1990	DET	@	TOR	LHP	31	12	1	0	6	2	0	2	33	25	5	0	0	0	.387	.424	.806	1.231
15	Tigers	4	8/18/1989	DET	vs	NYY	LHP	16	6	1	0	6	0	0	3	16	19	5	0	0	0	.375	.375	1.188	1.563
16	Tigers	4	6/14/1985	DET	@	NYY	LHP	27	8	0	0	4	3	0	5	30	20	4	0	0	0	.296	.367	.741	1.107
17	Tigers	4	5/25/1980	DET	@	BAL	LHP	35	8	0	0	4	5	1	5	42	20	4	1	0	1	.229	.341	.571	.913
18	Tigers	4	7/29/1974	DET	@	CLE	LHP	19	6	1	0	5	1	0	3	20	19	5	0	0	0	.316	.350	1.000	1.350
19	Tigers	3	4/23/2025	DET	vs	SDP	LHP	29	10	1	0	6	1	0	8	30	20	4	0	0	0	.345	.367	.690	1.056
20	Tigers	3	6/14/2023	DET	vs	ATL	LHP	19	6	0	0	5	3	0	3	22	15	3	0	0	0	.316	.409	.789	1.199
21	Tigers	3	9/7/2022	DET	@	LAA	LHP	24	8	0	0	3	2	0	4	26	17	3	0	0	0	.333	.385	.708	1.093
22	Tigers	3	7/25/2022	DET	vs	SDP	LHP	27	10	1	0	10	3	0	5	31	20	4	0	1	0	.370	.419	.741	1.160
23	Tigers	3	8/31/2021	DET	vs	OAK	LHP	28	9	1	0	3	2	0	5	30	19	4	0	0	0	.321	.367	.679	1.045
24	Tigers	3	8/12/2021	DET	@	BAL	LHP	23	8	1	1	6	1	0	3	24	20	5	0	0	0	.348	.375	.870	1.245
25	Tigers	3	6/10/2021	DET	vs	SEA	LHP	30	11	2	0	7	2	0	5	33	22	5	0	1	0	.367	.394	.733	1.127