Andy Pettitte has allowed the most career runs in the postseason, with 121 runs.

	NAME	R	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Andy Pettitte A. Pettitte	121	44	19	11	.633	44	3.81	183	0	0	0	276.2	285	117	31	76	3	0	4	1,157	4	5.95	2.47	2.41	1.01	15.8	6.6	1.30	.294	3.94	9.27
2	Clayton Kershaw C. Kershaw	102	39	13	13	.500	32	4.49	213	0	0	1	194.1	165	97	30	51	4	2	5	788	11	9.86	2.36	4.18	1.39	27.0	6.5	1.11	.276	4.72	7.64
3	Greg Maddux G. Maddux	97	35	11	14	.440	30	3.27	125	2	0	1	198.0	195	72	14	51	9	2	16	836	4	5.68	2.32	2.45	0.64	15.0	6.1	1.24	.284	4.41	8.86
4	Justin Verlander J. Verlander	93	38	17	12	.586	37	3.58	244	2	1	0	226.0	179	90	32	74	5	0	0	920	8	9.72	2.95	3.30	1.27	26.5	8.0	1.12	.260	3.70	7.13
5	Tom Glavine T. Glavine	91	35	14	16	.467	35	3.30	143	3	0	0	218.1	191	80	21	87	7	0	11	912	3	5.89	3.59	1.64	0.87	15.7	9.5	1.27	.260	3.75	7.87
6	Roger Clemens R. Clemens	87	35	12	8	.600	34	3.75	173	1	1	0	199.0	173	83	17	70	6	1	1	837	10	7.82	3.17	2.47	0.77	20.7	8.4	1.22	.273	3.93	7.82
7	CC Sabathia	67	26	10	7	.588	23	4.28	121	1	0	0	130.1	137	62	15	63	8	0	9	586	5	8.36	4.35	1.92	1.04	20.6	10.8	1.53	.322	4.63	9.46
8	John Smoltz J. Smoltz	67	41	15	4	.789	27	2.67	199	2	1	4	209.0	172	62	17	67	3	11	6	856	6	8.57	2.89	2.97	0.73	23.2	7.8	1.14	.272	2.89	7.41
9	Max Scherzer M. Scherzer	63	30	7	8	.467	25	3.78	171	0	0	1	143.0	109	60	20	56	9	1	4	594	8	10.76	3.52	3.05	1.26	28.8	9.4	1.15	.263	3.97	6.86
10	John Lackey J. Lackey	58	29	8	6	.571	23	3.44	114	0	0	0	144.0	135	55	7	47	4	2	6	601	10	7.13	2.94	2.43	0.44	19.0	7.8	1.26	.298	3.63	8.44
11	Mike Mussina M. Mussina	56	23	7	8	.467	21	3.42	145	0	0	0	139.2	121	53	19	33	3	0	7	571	2	9.34	2.13	4.39	1.22	25.4	5.8	1.10	.275	3.61	7.80
12	Tim Wakefield T. Wakefield	56	18	5	7	.417	11	6.75	54	2	0	0	72.0	68	54	13	38	9	2	2	329	1	6.75	4.75	1.42	1.63	16.4	11.6	1.47	.256	7.00	8.50
13	Zack Greinke Z. Greinke	55	22	4	6	.400	21	4.14	100	0	0	0	113.0	103	52	19	33	3	0	0	469	2	7.96	2.63	3.03	1.51	21.3	7.0	1.20	.268	4.38	8.20
14	David Price D. Price	53	23	5	9	.357	14	4.62	91	0	0	1	99.1	91	51	16	28	3	5	1	414	1	8.24	2.54	3.25	1.45	22.0	6.8	1.20	.272	4.80	8.24
15	David Cone D. Cone	52	21	8	3	.727	18	3.80	94	1	0	0	111.1	93	47	12	58	2	2	1	480	6	7.60	4.69	1.62	0.97	19.6	12.1	1.36	.258	4.20	7.52
16	Randy Johnson R. Johnson	51	19	7	9	.438	16	3.50	132	3	2	0	121.0	106	47	15	32	0	2	2	493	0	9.82	2.38	4.13	1.12	26.8	6.5	1.14	.290	3.79	7.88
17	Whitey Ford W. Ford	51	22	10	8	.556	22	2.71	94	7	3	0	146.0	132	44	8	34	3	0	2	594	4	5.79	2.10	2.76	0.49	15.8	5.7	1.14	.273	3.14	8.14
18	Gerrit Cole G. Cole	50	22	11	6	.647	22	2.77	156	0	0	0	133.1	100	41	19	36	3	0	1	537	1	10.53	2.43	4.33	1.28	29.1	6.7	1.02	.251	3.38	6.75
19	Charles Nagy C. Nagy	49	15	3	4	.429	14	4.46	55	0	0	0	84.2	87	42	14	30	3	1	3	372	0	5.85	3.19	1.83	1.49	14.8	8.1	1.38	.270	5.21	9.25
20	David Wells D. Wells	49	27	10	5	.667	17	3.17	83	1	0	0	125.0	116	44	12	25	7	2	2	508	1	5.98	1.80	3.32	0.86	16.3	4.9	1.13	.273	3.53	8.35
21	Catfish Hunter C. Hunter	49	22	9	6	.600	19	3.26	70	4	1	1	132.1	114	48	21	35	1	2	6	536	2	4.76	2.38	2.00	1.43	13.1	6.5	1.13	.227	3.33	7.75
22	Al Leiter A. Leiter	47	21	2	3	.400	11	4.63	68	0	0	0	81.2	81	42	9	36	3	0	4	352	2	7.49	3.97	1.89	0.99	19.3	10.2	1.43	.305	5.18	8.93
23	Jon Lester J. Lester	46	26	9	7	.563	22	2.51	133	0	0	0	154.0	117	43	15	40	3	2	0	610	4	7.77	2.34	3.33	0.88	21.8	6.6	1.02	.243	2.69	6.84
24	Jaret Wright J. Wright	46	16	3	6	.333	10	7.07	48	0	0	0	56.0	61	44	16	34	2	0	1	258	2	7.71	5.46	1.41	2.57	18.6	13.2	1.70	.285	7.39	9.80
25	Don Sutton D. Sutton	46	15	6	4	.600	14	3.68	61	3	1	0	100.1	92	41	12	16	3	0	0	407	2	5.47	1.44	3.81	1.08	15.0	3.9	1.08	.254	4.13	8.25