The Colorado Rockies had the highest ERA by a team in 2022, with an ERA of 5.06.

	TEAM	ERA	SEASON	G	W%	W	L	GS	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Rockies	5.06	2022	162	.420	68	94	162	1,187	1	1	43	1425.1	1,516	802	873	184	539	59	12	6,240	65	7.50	3.40	2.20	1.16	19.0	8.6	1.44	.312	5.51	9.57
2	Nationals	5.00	2022	162	.340	55	107	162	1,220	2	0	28	1411.2	1,469	785	855	244	558	75	12	6,220	59	7.78	3.56	2.19	1.56	19.6	9.0	1.44	.297	5.45	9.37
3	Reds	4.86	2022	162	.383	62	100	162	1,414	1	1	31	1423.1	1,366	768	815	213	612	110	21	6,220	58	8.94	3.87	2.31	1.35	22.7	9.8	1.39	.298	5.15	8.64
4	Royals	4.70	2022	162	.401	65	97	162	1,191	0	0	33	1416.0	1,493	740	810	173	589	71	15	6,249	88	7.57	3.74	2.02	1.10	19.1	9.4	1.47	.312	5.15	9.49
5	Pirates	4.66	2022	162	.383	62	100	162	1,250	0	0	33	1421.0	1,432	735	817	164	586	87	23	6,263	62	7.92	3.71	2.13	1.04	20.0	9.4	1.42	.304	5.17	9.07
6	Red Sox	4.53	2022	162	.481	78	84	162	1,346	5	2	39	1431.0	1,411	721	787	185	526	72	17	6,167	60	8.47	3.31	2.56	1.16	21.8	8.5	1.35	.304	4.95	8.87
7	Athletics	4.52	2022	162	.370	60	102	162	1,203	0	0	34	1426.1	1,394	717	770	195	503	72	37	6,121	62	7.59	3.17	2.39	1.23	19.7	8.2	1.33	.289	4.86	8.80
8	Diamondbacks	4.25	2022	162	.457	74	88	162	1,216	0	0	33	1430.0	1,345	676	740	191	504	59	18	6,065	51	7.65	3.17	2.41	1.20	20.0	8.3	1.29	.282	4.66	8.47
9	Rangers	4.22	2022	162	.420	68	94	162	1,314	1	1	37	1435.0	1,345	673	743	169	581	71	16	6,167	66	8.24	3.64	2.26	1.06	21.3	9.4	1.34	.292	4.66	8.44
10	Tigers	4.04	2022	162	.407	66	96	162	1,195	0	0	38	1419.2	1,336	637	713	167	511	57	9	6,047	59	7.58	3.24	2.34	1.06	19.8	8.5	1.30	.284	4.52	8.47
11	Cubs	4.00	2022	162	.457	74	88	162	1,383	0	0	44	1443.2	1,342	642	731	207	540	73	19	6,162	53	8.62	3.37	2.56	1.29	22.4	8.8	1.30	.287	4.56	8.37
12	Twins	3.98	2022	162	.481	78	84	162	1,336	0	0	28	1437.0	1,320	636	684	184	468	66	19	6,042	50	8.37	2.93	2.85	1.15	22.1	7.7	1.24	.285	4.28	8.27
13	Phillies	3.97	2022	162	.537	87	75	162	1,423	3	1	42	1428.1	1,330	630	685	150	463	68	16	6,006	47	8.97	2.92	3.07	0.95	23.7	7.7	1.26	.302	4.32	8.38
14	Orioles	3.97	2022	162	.512	83	79	162	1,214	2	1	46	1433.1	1,406	632	688	171	443	64	8	6,058	47	7.62	2.78	2.74	1.07	20.0	7.3	1.29	.296	4.32	8.83
15	White Sox	3.92	2022	162	.500	81	81	162	1,450	2	1	48	1447.2	1,330	631	717	166	533	51	15	6,145	64	9.01	3.31	2.72	1.03	23.6	8.7	1.29	.295	4.46	8.27
16	Blue Jays	3.87	2022	162	.568	92	70	162	1,390	0	0	46	1441.1	1,356	620	679	180	424	76	15	6,053	29	8.68	2.65	3.28	1.12	23.0	7.0	1.23	.295	4.24	8.47
17	Marlins	3.87	2022	162	.426	69	93	162	1,437	6	1	41	1437.1	1,311	618	676	173	511	76	19	6,056	54	9.00	3.20	2.81	1.08	23.7	8.4	1.27	.295	4.23	8.21
18	Giants	3.85	2022	162	.500	81	81	162	1,370	1	0	39	1433.0	1,397	613	697	132	441	52	16	6,070	53	8.60	2.77	3.11	0.83	22.6	7.3	1.28	.310	4.38	8.77
19	Brewers	3.83	2022	162	.531	86	76	162	1,530	0	0	52	1446.0	1,238	615	688	190	521	67	12	6,057	47	9.52	3.24	2.94	1.18	25.3	8.6	1.22	.280	4.28	7.71
20	Padres	3.81	2022	162	.549	89	73	162	1,451	0	0	48	1443.1	1,263	611	660	173	468	88	6	6,047	54	9.05	2.92	3.10	1.08	24.0	7.7	1.20	.282	4.12	7.88
21	Cardinals	3.79	2022	162	.574	93	69	162	1,177	3	1	37	1435.2	1,335	605	637	146	489	60	11	6,014	43	7.38	3.07	2.41	0.92	19.6	8.1	1.27	.287	3.99	8.37
22	Angels	3.77	2022	162	.451	73	89	162	1,383	2	2	38	1435.2	1,241	601	668	168	540	60	23	6,038	64	8.67	3.39	2.56	1.05	22.9	8.9	1.24	.276	4.19	7.78
23	Mariners	3.59	2022	162	.556	90	72	162	1,391	0	0	40	1447.0	1,277	577	623	186	447	56	24	5,986	45	8.65	2.78	3.11	1.16	23.2	7.5	1.19	.279	3.87	7.94
24	Mets	3.57	2022	162	.623	101	61	162	1,565	0	0	41	1438.2	1,274	570	606	169	428	71	13	5,950	35	9.79	2.68	3.66	1.06	26.3	7.2	1.18	.297	3.79	7.97
25	Guardians	3.46	2022	162	.568	92	70	162	1,390	1	0	51	1456.0	1,252	560	634	172	435	57	14	5,989	49	8.59	2.69	3.20	1.06	23.2	7.3	1.16	.274	3.92	7.74