Between June 16, 2025 and June 20, 2025, the St. Louis Cardinals and the Houston Astros are tied for the highest run differential, with a differential of 13 runs this season.
| TEAM | DIFF | SEASON | G | W% | W | L | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 13 | 2025 | 3 | 1.000 | 3 | 0 | 112 | 25 | 33 | 5 | 0 | 6 | 23 | 13 | 3 | 27 | 2 | 1 | 130 | 56 | 11 | 1 | 1 | 1 | 1 | .295 | .380 | .500 | .880 |
| 2 |  | Astros | 13 | 2025 | 4 | .500 | 2 | 2 | 153 | 29 | 51 | 8 | 0 | 10 | 28 | 16 | 5 | 31 | 0 | 2 | 174 | 89 | 18 | 0 | 0 | 0 | 7 | .333 | .414 | .582 | .995 |
| 3 |  | Braves | 12 | 2025 | 3 | 1.000 | 3 | 0 | 96 | 17 | 22 | 5 | 1 | 2 | 15 | 18 | 0 | 16 | 0 | 0 | 116 | 35 | 8 | 0 | 2 | 1 | 2 | .229 | .345 | .365 | .709 |
| 4 |  | Royals | 11 | 2025 | 3 | 1.000 | 3 | 0 | 100 | 16 | 21 | 5 | 1 | 7 | 16 | 10 | 0 | 15 | 2 | 1 | 111 | 49 | 13 | 1 | 0 | 2 | 1 | .210 | .282 | .490 | .772 |
| 5 |  | Tigers | 7 | 2025 | 3 | .667 | 2 | 1 | 97 | 20 | 26 | 7 | 1 | 6 | 20 | 12 | 2 | 23 | 0 | 0 | 115 | 53 | 14 | 0 | 4 | 0 | 2 | .268 | .348 | .546 | .894 |
| 6 |  | Rockies | 7 | 2025 | 4 | .750 | 3 | 1 | 144 | 22 | 37 | 6 | 2 | 12 | 22 | 7 | 4 | 41 | 3 | 2 | 156 | 83 | 20 | 1 | 0 | 0 | 4 | .257 | .310 | .576 | .886 |
| 7 |  | Twins | 4 | 2025 | 3 | .333 | 1 | 2 | 100 | 19 | 28 | 7 | 0 | 7 | 19 | 12 | 3 | 25 | 0 | 1 | 115 | 56 | 14 | 0 | 0 | 0 | 0 | .280 | .374 | .560 | .934 |
| 8 |  | Blue Jays | 4 | 2025 | 3 | .667 | 2 | 1 | 99 | 18 | 28 | 8 | 0 | 7 | 18 | 9 | 6 | 20 | 0 | 1 | 115 | 57 | 15 | 0 | 1 | 1 | 3 | .283 | .374 | .576 | .950 |
| 9 |  | Dodgers | 4 | 2025 | 4 | .750 | 3 | 1 | 131 | 21 | 35 | 7 | 1 | 4 | 20 | 13 | 4 | 30 | 2 | 0 | 150 | 56 | 12 | 0 | 2 | 1 | 3 | .267 | .347 | .427 | .774 |
| 10 |  | Mariners | 4 | 2025 | 3 | .333 | 1 | 2 | 93 | 9 | 19 | 5 | 0 | 1 | 8 | 11 | 0 | 31 | 4 | 0 | 105 | 27 | 6 | 0 | 1 | 0 | 2 | .204 | .286 | .290 | .576 |
| 11 |  | Rays | 3 | 2025 | 4 | .500 | 2 | 2 | 138 | 21 | 47 | 7 | 2 | 3 | 21 | 13 | 2 | 37 | 4 | 1 | 155 | 67 | 12 | 2 | 0 | 0 | 4 | .341 | .405 | .486 | .891 |
| 12 |  | Guardians | 2 | 2025 | 3 | .667 | 2 | 1 | 99 | 8 | 20 | 6 | 1 | 2 | 8 | 5 | 0 | 28 | 3 | 1 | 105 | 34 | 9 | 0 | 1 | 0 | 0 | .202 | .238 | .343 | .582 |
| 13 |  | Angels | 2 | 2025 | 4 | .750 | 3 | 1 | 140 | 11 | 28 | 2 | 1 | 5 | 11 | 9 | 3 | 37 | 2 | 1 | 153 | 47 | 8 | 1 | 0 | 2 | 1 | .200 | .263 | .336 | .599 |
| 14 |  | Cubs | 1 | 2025 | 2 | .500 | 1 | 1 | 63 | 12 | 14 | 3 | 0 | 5 | 12 | 7 | 3 | 17 | 0 | 0 | 73 | 32 | 8 | 0 | 0 | 0 | 2 | .222 | .329 | .508 | .837 |
| 15 |  | Phillies | 1 | 2025 | 4 | .750 | 3 | 1 | 137 | 14 | 33 | 7 | 1 | 5 | 14 | 11 | 3 | 27 | 1 | 1 | 151 | 57 | 13 | 0 | 0 | 0 | 1 | .241 | .311 | .416 | .727 |
| 16 |  | Brewers | -1 | 2025 | 2 | .500 | 1 | 1 | 72 | 11 | 21 | 6 | 0 | 4 | 11 | 7 | 1 | 17 | 3 | 2 | 80 | 39 | 10 | 0 | 0 | 1 | 1 | .292 | .363 | .542 | .904 |
| 17 |  | Marlins | -1 | 2025 | 4 | .250 | 1 | 3 | 132 | 13 | 31 | 2 | 2 | 3 | 13 | 9 | 2 | 30 | 2 | 0 | 145 | 46 | 7 | 0 | 2 | 0 | 3 | .235 | .290 | .348 | .638 |
| 18 |  | Giants | -2 | 2025 | 3 | .333 | 1 | 2 | 93 | 6 | 21 | 3 | 0 | 1 | 6 | 12 | 3 | 24 | 0 | 1 | 110 | 27 | 4 | 2 | 0 | 0 | 3 | .226 | .333 | .290 | .624 |
| 19 |  | Yankees | -2 | 2025 | 4 | .250 | 1 | 3 | 130 | 9 | 27 | 6 | 0 | 4 | 9 | 12 | 1 | 38 | 2 | 2 | 145 | 45 | 10 | 1 | 1 | 2 | 3 | .208 | .278 | .346 | .624 |
| 20 |  | Orioles | -3 | 2025 | 4 | .500 | 2 | 2 | 133 | 18 | 30 | 3 | 0 | 6 | 18 | 10 | 2 | 36 | 2 | 2 | 145 | 51 | 9 | 0 | 0 | 1 | 3 | .226 | .290 | .383 | .673 |
| 21 |  | Reds | -4 | 2025 | 3 | .667 | 2 | 1 | 92 | 15 | 24 | 5 | 0 | 2 | 15 | 9 | 1 | 23 | 2 | 1 | 102 | 35 | 7 | 0 | 0 | 0 | 0 | .261 | .333 | .380 | .714 |
| 22 |  | Diamondbacks | -4 | 2025 | 3 | .333 | 1 | 2 | 100 | 14 | 23 | 5 | 1 | 2 | 13 | 11 | 4 | 27 | 1 | 2 | 117 | 36 | 8 | 0 | 2 | 0 | 0 | .230 | .325 | .360 | .685 |
| 23 |  | Red Sox | -4 | 2025 | 3 | .667 | 2 | 1 | 88 | 5 | 9 | 0 | 1 | 3 | 5 | 7 | 2 | 29 | 1 | 0 | 97 | 20 | 4 | 0 | 0 | 0 | 2 | .102 | .186 | .227 | .413 |
| 24 |  | Padres | -4 | 2025 | 4 | .250 | 1 | 3 | 132 | 17 | 33 | 8 | 1 | 3 | 16 | 9 | 4 | 31 | 2 | 0 | 150 | 52 | 12 | 1 | 4 | 1 | 5 | .250 | .309 | .394 | .703 |
| 25 |  | Pirates | -7 | 2025 | 3 | .333 | 1 | 2 | 104 | 13 | 23 | 3 | 0 | 3 | 13 | 9 | 0 | 29 | 1 | 1 | 115 | 35 | 6 | 1 | 1 | 1 | 1 | .221 | .281 | .337 | .617 |
Some of the information used here was obtained free of charge from Retrosheet.
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