The New York Yankees have the highest run differential by a team this season, with a differential of 110 runs.

Interpreted as:

Who has the best run differential this regular season?

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	110	2025	77	.584	45	32	2,606	395	666	133	12	118	380	305	32	679	54	20	2,974	1,177	263	3	28	21	52	.256	.338	.452	.789
2	Cubs	104	2025	76	.605	46	30	2,626	411	667	137	15	109	403	268	21	602	90	15	2,944	1,161	261	6	23	9	34	.254	.325	.442	.768
3	Tigers	82	2025	79	.620	49	30	2,673	391	674	129	15	96	377	257	34	692	28	6	2,993	1,121	240	4	25	7	45	.252	.323	.419	.742
4	Dodgers	72	2025	78	.603	47	31	2,662	429	701	132	13	120	411	295	29	634	44	13	3,018	1,219	265	3	29	17	58	.263	.340	.458	.798
5	Rays	70	2025	78	.551	43	35	2,623	371	671	125	6	84	352	244	28	654	104	23	2,922	1,060	215	7	20	3	52	.256	.323	.404	.728
6	Mets	67	2025	77	.597	46	31	2,578	346	635	124	13	102	337	278	48	601	61	10	2,931	1,091	239	3	24	14	65	.246	.328	.423	.751
7	Astros	45	2025	77	.571	44	33	2,581	325	661	111	7	81	310	225	35	599	43	18	2,870	1,029	199	9	20	7	66	.256	.322	.399	.721
8	Giants	42	2025	77	.558	43	34	2,523	323	583	111	12	73	305	278	28	648	42	16	2,865	937	196	14	22	6	51	.231	.312	.371	.683
9	Brewers	40	2025	77	.545	42	35	2,567	353	623	112	8	69	328	266	31	633	94	25	2,904	958	189	17	23	10	38	.243	.319	.373	.692
10	Phillies	35	2025	77	.597	46	31	2,622	362	674	122	11	81	345	271	30	599	65	15	2,946	1,061	214	7	16	9	47	.257	.332	.405	.736
11	Reds	34	2025	78	.513	40	38	2,615	360	643	131	9	86	345	269	24	682	63	23	2,934	1,050	226	6	20	7	47	.246	.320	.402	.721
12	Cardinals	34	2025	78	.538	42	36	2,656	366	676	133	4	74	346	252	43	612	43	14	2,982	1,039	211	9	22	12	56	.255	.327	.391	.718
13	Braves	25	2025	76	.461	35	41	2,576	319	630	107	7	80	306	264	22	641	39	12	2,886	991	194	7	17	9	48	.245	.318	.385	.703
14	Padres	24	2025	76	.539	41	35	2,534	322	634	114	11	65	298	239	21	536	55	15	2,837	965	190	18	25	8	53	.250	.317	.381	.698
15	Red Sox	19	2025	78	.513	40	38	2,692	367	668	145	11	94	350	264	36	722	65	15	3,013	1,117	250	6	15	15	43	.248	.322	.415	.737
16	Rangers	16	2025	78	.487	38	40	2,555	282	583	108	8	78	270	218	29	630	63	18	2,825	941	194	3	20	6	41	.228	.294	.368	.662
17	Mariners	4	2025	75	.507	38	37	2,562	333	627	105	4	96	321	270	39	668	76	20	2,898	1,028	205	11	16	7	45	.245	.324	.401	.725
18	Diamondbacks	-1	2025	76	.513	39	37	2,580	394	661	138	17	110	386	277	35	589	57	17	2,935	1,163	265	13	30	9	52	.256	.333	.451	.784
19	Twins	-9	2025	76	.487	37	39	2,548	320	614	121	8	82	308	227	47	629	36	14	2,839	997	211	1	16	4	50	.241	.313	.391	.704
20	Blue Jays	-10	2025	77	.532	41	36	2,595	330	664	132	4	79	317	246	29	520	38	12	2,910	1,041	215	16	24	13	60	.256	.324	.401	.726
21	Royals	-20	2025	77	.494	38	39	2,587	260	639	126	15	55	256	184	25	524	61	26	2,837	960	196	18	23	12	38	.247	.301	.371	.672
22	Guardians	-26	2025	75	.507	38	37	2,446	283	562	107	7	75	268	230	27	616	60	17	2,737	908	189	9	25	11	46	.230	.300	.371	.671
23	Angels	-53	2025	76	.487	37	39	2,533	314	570	99	8	110	303	192	40	740	35	14	2,789	1,015	217	7	17	9	43	.225	.288	.401	.689
24	Pirates	-61	2025	79	.392	31	48	2,608	257	593	98	13	53	247	260	29	681	71	22	2,922	876	164	8	17	11	69	.227	.303	.336	.639
25	Nationals	-67	2025	77	.416	32	45	2,560	322	614	126	10	80	306	216	38	573	64	26	2,844	1,000	216	14	16	4	49	.240	.307	.391	.697