The Colorado Rockies have the lowest run differential by a team this season, with a differential of -203 runs.

Interpreted as:

worst point differential in MLB this regular season

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	-203	2025	71	.197	14	57	2,362	239	530	112	23	61	235	196	25	691	32	16	2,605	871	196	7	15	5	51	.224	.289	.369	.658
2	Athletics	-113	2025	73	.397	29	44	2,505	312	636	125	8	90	303	236	16	599	41	9	2,775	1,047	223	4	14	5	65	.254	.320	.418	.738
3	Marlins	-88	2025	69	.406	28	41	2,364	282	595	115	8	61	271	206	16	558	54	24	2,618	909	184	14	18	5	41	.252	.314	.385	.698
4	Orioles	-73	2025	70	.429	30	40	2,331	279	562	104	9	81	260	199	30	617	51	14	2,583	927	194	2	21	5	57	.241	.306	.398	.704
5	Nationals	-63	2025	71	.423	30	41	2,355	295	564	116	10	66	280	198	37	539	58	23	2,614	898	192	10	14	3	46	.239	.307	.381	.688
6	White Sox	-62	2025	72	.319	23	49	2,353	248	523	111	4	55	238	235	14	628	51	15	2,631	807	170	10	19	3	40	.222	.295	.343	.638
7	Angels	-62	2025	70	.471	33	37	2,321	292	525	94	7	100	281	177	33	682	33	13	2,554	933	201	6	17	7	42	.226	.288	.402	.690
8	Pirates	-54	2025	73	.397	29	44	2,402	232	541	90	13	50	222	244	28	632	68	21	2,694	807	153	6	14	10	66	.225	.302	.336	.638
9	Royals	-28	2025	72	.472	34	38	2,420	237	604	116	14	46	233	168	24	496	56	24	2,651	886	176	16	23	10	37	.250	.302	.366	.668
10	Guardians	-26	2025	70	.500	35	35	2,278	270	528	95	6	72	255	220	27	570	56	16	2,558	851	173	9	24	10	46	.232	.304	.374	.678
11	Blue Jays	-12	2025	71	.535	38	33	2,394	302	608	121	3	70	290	230	23	486	38	11	2,686	945	194	16	23	12	54	.254	.322	.395	.717
12	Diamondbacks	-5	2025	71	.507	36	35	2,401	361	607	127	15	102	354	260	31	552	54	15	2,730	1,070	244	12	26	9	49	.253	.330	.446	.776
13	Mariners	-2	2025	70	.514	36	34	2,391	308	581	93	4	90	298	254	37	618	71	20	2,707	952	187	11	14	7	41	.243	.323	.398	.722
14	Twins	7	2025	71	.507	36	35	2,387	295	577	112	8	74	283	207	44	591	36	13	2,654	927	194	1	15	4	48	.242	.312	.388	.700
15	Braves	12	2025	70	.443	31	39	2,375	290	583	96	6	76	279	238	22	604	37	12	2,657	919	178	7	15	7	45	.245	.318	.387	.705
16	Cardinals	18	2025	72	.514	37	35	2,444	328	624	125	4	66	312	228	37	562	39	13	2,737	955	195	8	20	10	54	.255	.326	.391	.717
17	Brewers	21	2025	73	.534	39	34	2,419	316	572	98	8	65	292	248	30	603	89	21	2,731	881	171	16	18	8	36	.236	.313	.364	.677
18	Red Sox	22	2025	73	.507	37	36	2,533	353	642	141	10	89	338	253	34	675	62	15	2,841	1,070	240	6	15	15	40	.253	.328	.422	.750
19	Padres	25	2025	70	.557	39	31	2,336	295	581	103	10	60	272	221	17	496	53	14	2,612	884	173	17	21	7	45	.249	.316	.378	.694
20	Rangers	27	2025	72	.500	36	36	2,356	265	539	97	6	76	256	200	25	579	62	17	2,603	876	179	3	19	6	36	.229	.294	.372	.666
21	Phillies	33	2025	71	.592	42	29	2,414	334	620	110	10	75	318	253	26	557	63	14	2,716	975	195	7	16	9	44	.257	.332	.404	.736
22	Astros	39	2025	71	.577	41	30	2,361	292	598	103	7	69	279	202	30	544	43	14	2,622	922	179	9	20	6	59	.253	.318	.391	.708
23	Reds	41	2025	72	.514	37	35	2,424	335	601	120	7	82	322	251	22	630	59	22	2,721	981	209	6	18	7	44	.248	.322	.405	.727
24	Giants	46	2025	71	.577	41	30	2,335	305	543	107	11	69	290	253	23	601	42	15	2,645	879	187	12	22	5	46	.233	.311	.376	.687
25	Rays	62	2025	71	.549	39	32	2,380	325	591	111	4	75	308	220	23	598	97	22	2,648	935	190	5	20	3	45	.248	.316	.393	.708