The New York Mets had the lowest run differential by a team in 1962, with a differential of -331 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mets	-331	1962	161	.250	40	120	5,492	617	1,318	166	40	139	573	616	32	991	59	48	6,242	1,981	345	58	44	29	122	.240	.318	.361	.679
2	Cubs	-195	1962	162	.364	59	103	5,534	632	1,398	196	56	126	600	504	39	1,044	78	50	6,173	2,084	378	54	42	43	131	.253	.317	.377	.694
3	Colt .45's	-125	1962	162	.400	64	96	5,558	592	1,370	170	47	105	549	493	38	806	42	30	6,198	1,949	322	75	34	37	132	.246	.310	.351	.661
4	Senators	-117	1962	162	.373	60	101	5,484	599	1,370	206	38	132	566	466	15	789	99	53	6,072	2,048	376	71	36	26	135	.250	.308	.373	.682
5	Athletics	-92	1962	162	.444	72	90	5,576	745	1,467	220	58	116	691	556	42	803	76	21	6,302	2,151	394	78	50	35	108	.263	.332	.386	.718
6	Indians	-63	1962	162	.494	80	82	5,484	682	1,341	202	22	180	644	502	54	939	35	16	6,137	2,127	404	52	45	27	117	.245	.312	.388	.700
7	Phillies	-54	1962	161	.503	81	80	5,420	705	1,410	199	39	142	658	531	53	923	79	42	6,131	2,113	380	83	44	38	121	.260	.330	.390	.720
8	Red Sox	-49	1962	160	.475	76	84	5,530	707	1,429	257	53	146	671	525	27	923	39	33	6,177	2,230	456	59	36	39	129	.258	.324	.403	.727
9	Orioles	-28	1962	162	.475	77	85	5,491	652	1,363	225	34	156	617	516	32	931	45	32	6,158	2,124	415	75	44	36	131	.248	.314	.387	.701
10	Angels	12	1962	162	.531	86	76	5,499	718	1,377	232	35	137	667	602	29	917	46	27	6,255	2,090	404	82	43	40	110	.250	.325	.380	.705
11	White Sox	49	1962	162	.525	85	77	5,514	707	1,415	250	56	92	662	620	41	674	76	40	6,297	2,053	398	82	40	41	132	.257	.334	.372	.706
12	Braves	65	1962	162	.531	86	76	5,458	730	1,376	204	38	181	685	581	34	975	57	27	6,155	2,199	423	47	35	44	133	.252	.326	.403	.729
13	Tigers	66	1962	161	.528	85	76	5,456	758	1,352	191	36	209	719	651	33	894	69	21	6,234	2,242	436	56	38	40	122	.248	.330	.411	.740
14	Pirates	80	1962	161	.578	93	68	5,483	706	1,468	240	65	108	655	432	17	836	50	39	6,035	2,162	413	54	49	52	123	.268	.321	.394	.715
15	Twins	85	1962	163	.562	91	71	5,561	798	1,445	215	39	185	758	649	31	823	33	20	6,362	2,293	439	71	50	36	129	.260	.338	.412	.750
16	Cardinals	110	1962	163	.519	84	78	5,643	774	1,528	221	31	137	707	515	45	846	86	41	6,307	2,222	389	69	35	41	129	.271	.335	.394	.728
17	Reds	117	1962	162	.605	98	64	5,645	802	1,523	252	40	167	745	498	41	903	66	39	6,273	2,356	459	57	32	62	114	.270	.332	.417	.749
18	Yankees	137	1962	162	.593	96	66	5,644	817	1,509	240	29	199	791	584	32	842	42	29	6,393	2,404	468	79	54	46	123	.267	.337	.426	.762
19	Dodgers	145	1962	165	.618	102	63	5,628	842	1,510	192	65	140	781	572	32	886	198	43	6,362	2,252	397	83	47	65	126	.268	.337	.400	.737
20	Giants	188	1962	165	.624	103	62	5,588	878	1,552	235	32	204	807	523	42	822	73	50	6,277	2,463	471	76	48	41	120	.278	.341	.441	.782