The Colorado Rockies have the lowest run differential by a team this season, with a differential of -175 runs.

Interpreted as:

worst run differtional this regular season

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	-175	2025	56	.161	9	47	1,851	177	404	84	15	46	175	155	17	549	27	13	2,041	656	145	7	11	5	37	.218	.283	.354	.638
2	Orioles	-97	2025	55	.345	19	36	1,844	213	437	80	7	60	200	157	25	493	38	13	2,043	711	147	2	15	3	42	.237	.303	.386	.689
3	Athletics	-89	2025	56	.411	23	33	1,925	235	491	91	7	69	226	176	10	440	27	7	2,125	803	167	3	11	5	54	.255	.319	.417	.736
4	Marlins	-76	2025	54	.407	22	32	1,853	229	466	89	8	51	219	165	14	446	46	18	2,056	724	148	11	13	5	32	.251	.315	.391	.706
5	Pirates	-60	2025	57	.368	21	36	1,893	183	428	69	10	40	177	200	21	490	56	13	2,128	637	119	5	9	10	53	.226	.306	.337	.642
6	Angels	-56	2025	55	.455	25	30	1,820	224	408	78	6	79	217	136	23	542	24	8	1,998	735	163	5	14	6	31	.224	.284	.404	.688
7	White Sox	-48	2025	56	.321	18	38	1,826	196	404	83	2	46	190	181	12	470	45	9	2,039	629	131	6	14	1	30	.221	.294	.344	.638
8	Nationals	-47	2025	55	.455	25	30	1,821	235	438	89	8	57	222	158	26	429	53	17	2,027	714	154	10	12	1	33	.241	.308	.392	.700
9	Blue Jays	-26	2025	55	.491	27	28	1,838	209	448	90	2	47	200	186	20	398	33	9	2,074	683	139	13	17	10	41	.244	.317	.372	.689
10	Guardians	-17	2025	55	.545	30	25	1,795	223	419	79	5	57	211	173	21	443	39	14	2,019	679	141	8	22	7	30	.233	.305	.378	.683
11	Rangers	-12	2025	57	.474	27	30	1,835	185	403	67	5	57	180	145	19	459	50	13	2,015	651	129	2	14	3	27	.220	.282	.355	.636
12	Diamondbacks	-6	2025	56	.482	27	29	1,904	279	484	110	11	77	272	202	27	423	49	11	2,164	847	198	8	23	7	37	.254	.331	.445	.776
13	Royals	-5	2025	57	.526	30	27	1,905	188	469	97	11	33	185	136	21	398	47	20	2,095	687	141	13	20	8	25	.246	.301	.361	.661
14	Brewers	1	2025	57	.509	29	28	1,890	246	438	76	5	48	225	199	24	464	74	17	2,140	668	129	14	13	8	27	.232	.311	.353	.664
15	Braves	8	2025	54	.463	25	29	1,834	220	455	76	6	57	211	183	16	458	33	11	2,050	714	139	6	11	4	35	.248	.320	.389	.709
16	Red Sox	12	2025	58	.466	27	31	2,016	275	509	106	8	71	263	197	24	522	54	13	2,253	844	185	5	11	12	27	.252	.325	.419	.743
17	Padres	18	2025	54	.574	31	23	1,804	233	457	79	7	52	213	169	13	379	41	11	2,014	706	138	12	16	6	34	.253	.319	.391	.711
18	Mariners	18	2025	54	.556	30	24	1,829	247	435	68	3	73	238	210	29	481	49	16	2,087	728	144	8	11	3	31	.238	.324	.398	.722
19	Rays	20	2025	55	.509	28	27	1,832	226	448	80	3	53	217	164	13	452	76	15	2,026	693	136	1	16	0	38	.245	.309	.378	.687
20	Twins	26	2025	55	.545	30	25	1,823	216	431	86	7	51	206	150	34	449	29	11	2,020	684	144	1	12	4	36	.236	.305	.375	.680
21	Reds	32	2025	57	.491	28	29	1,924	264	478	100	7	58	252	199	20	508	54	19	2,158	766	165	3	12	5	32	.248	.323	.398	.722
22	Astros	36	2025	55	.545	30	25	1,829	230	468	77	6	54	220	167	27	417	25	13	2,046	719	137	8	15	6	44	.256	.325	.393	.718
23	Giants	39	2025	56	.554	31	25	1,845	242	427	84	8	55	231	195	16	473	26	12	2,077	692	147	9	12	4	36	.231	.309	.375	.684
24	Phillies	45	2025	55	.655	36	19	1,881	267	490	85	8	60	253	208	20	434	53	11	2,129	771	153	5	15	6	36	.260	.338	.410	.748
25	Cardinals	45	2025	56	.571	32	24	1,906	269	500	106	4	52	255	183	26	436	35	11	2,138	770	162	6	17	9	43	.262	.333	.404	.737