Max Kepler and José Ramírez were tied for the most homers on April 27, 2022, with 2 home runs.

Interpreted as:

4/27/22 most home runs by a player

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	SO	PA	TB	XBH	SF	GIDP	AVG	OBP	SLG	OPS
1	Max Kepler M. Kepler	2	1	3	2	2	0	0	2	1	0	4	8	2	0	0	.667	.750	2.667	3.417
2	José Ramírez J. Ramírez	2	1	4	2	2	0	0	4	0	0	4	8	2	0	0	.500	.500	2.000	2.500
3	Jesus Aguilar J. Aguilar	1	1	2	1	1	0	0	1	2	0	4	4	1	0	1	.500	.750	2.000	2.750
4	Nick Ahmed N. Ahmed	1	1	3	1	1	0	0	1	0	0	3	4	1	0	0	.333	.333	1.333	1.667
5	J.P. Crawford	1	1	4	1	1	0	0	1	0	1	4	4	1	0	0	.250	.250	1.000	1.250
6	C.J. Cron	1	1	4	1	1	0	0	1	0	0	4	4	1	0	0	.250	.250	1.000	1.250
7	Brandon Drury B. Drury	1	1	5	1	2	0	0	1	0	2	5	5	1	0	0	.400	.400	1.000	1.400
8	Joey Gallo J. Gallo	1	1	4	1	1	0	0	1	0	3	4	4	1	0	0	.250	.250	1.000	1.250
9	Mitch Garver M. Garver	1	1	4	1	2	0	0	1	0	0	4	5	1	0	0	.500	.500	1.250	1.750
10	Odubel Herrera O. Herrera	1	1	4	1	1	0	0	2	0	1	5	4	1	1	0	.250	.200	1.000	1.200
11	Eric Hosmer E. Hosmer	1	1	2	1	2	0	0	2	2	0	4	5	1	0	0	1.000	1.000	2.500	3.500
12	Kevin Kiermaier K. Kiermaier	1	1	3	1	2	0	0	2	0	0	3	5	1	0	0	.667	.667	1.667	2.333
13	Tommy Pham T. Pham	1	1	4	3	2	0	0	1	1	2	5	5	1	0	0	.500	.600	1.250	1.850
14	Chad Pinder C. Pinder	1	1	4	1	2	0	0	1	0	2	4	5	1	0	0	.500	.500	1.250	1.750
15	Jurickson Profar J. Profar	1	1	3	2	1	0	0	3	2	0	5	4	1	0	0	.333	.600	1.333	1.933
16	Anthony Santander A. Santander	1	1	4	1	1	0	0	2	0	2	4	4	1	0	0	.250	.250	1.000	1.250
17	Giancarlo Stanton G. Stanton	1	1	3	1	2	0	0	3	0	1	4	5	1	1	0	.667	.500	1.667	2.167
18	Taylor Ward T. Ward	1	1	4	4	3	1	1	4	1	0	5	9	3	0	0	.750	.800	2.250	3.050
19	Patrick Wisdom P. Wisdom	1	1	4	2	1	0	0	2	1	2	5	4	1	0	0	.250	.400	1.000	1.400
20	Abraham Toro A. Toro	1	1	4	1	1	0	0	1	0	2	4	4	1	0	0	.250	.250	1.000	1.250
21	Chas McCormick C. McCormick	1	1	5	2	2	0	0	1	0	0	5	5	1	0	1	.400	.400	1.000	1.400
22	Jake Burger J. Burger	1	1	4	1	3	1	0	1	0	0	4	7	2	0	0	.750	.750	1.750	2.500
23	Ryan Jeffers R. Jeffers	1	1	3	1	2	1	0	3	0	0	3	6	2	0	0	.667	.667	2.000	2.667
24	Andrew Vaughn A. Vaughn	1	1	4	1	2	1	0	4	0	0	4	6	2	0	0	.500	.500	1.500	2.000

StatMuse has game-level data for home runs going back to the 1901 season.

Some of the information used here was obtained free of charge from Retrosheet.

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Max Kepler and José Ramírez were tied for the most homers on April 27, 2022, with 2 home runs.

Interpreted as:

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