Clay Holmes has a record of 19-15 with an ERA of 2.69, 238 strikeouts and 74 saves in 220 appearances for the Yankees in his career.
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Holmes | 2021 |  NYY | 25 | 5 | 2 | .714 | 0 | 1.61 | 34 | 0 | 0 | 0 | 28.0 | 18 | 5 | 8 | 2 | 4 | 0 | 5 | 0 | 103 | 4 | 10.93 | 1.29 | 8.50 | 0.64 | 33.0 | 3.9 | 0.79 | .254 | 2.57 | 38 | 2.09 | 48 | 5.79 | 6.9 |
| 2 | | C. Holmes | 2022 | NYY | 62 | 7 | 4 | .636 | 0 | 2.54 | 65 | 0 | 0 | 20 | 63.2 | 45 | 18 | 21 | 2 | 20 | 9 | 32 | 2 | 260 | 1 | 9.19 | 2.83 | 3.25 | 0.28 | 25.0 | 7.7 | 1.02 | .262 | 2.97 | 67 | 2.84 | 71 | 6.36 | 8 |
| 3 | | C. Holmes | 2023 | NYY | 66 | 4 | 4 | .500 | 0 | 2.86 | 71 | 0 | 0 | 24 | 63.0 | 51 | 20 | 22 | 2 | 23 | 3 | 41 | 0 | 262 | 5 | 10.14 | 3.29 | 3.09 | 0.29 | 27.1 | 8.8 | 1.17 | .301 | 3.14 | 67 | 2.65 | 60 | 7.29 | 12 |
| 4 | | C. Holmes | 2024 | NYY | 67 | 3 | 5 | .375 | 0 | 3.14 | 68 | 0 | 0 | 30 | 63.0 | 60 | 22 | 29 | 4 | 22 | 3 | 50 | 1 | 271 | 4 | 9.71 | 3.14 | 3.09 | 0.57 | 25.1 | 8.1 | 1.30 | .322 | 4.14 | 78 | 3.02 | 72 | 8.57 | 8.2 |
| Total | 220 | 19 | 15 | .559 | 0 | 2.69 | 238 | 0 | 0 | 74 | 217.2 | 174 | 65 | 80 | 10 | 69 | 15 | 128 | 3 | 896 | 14 | 9.84 | 2.85 | 3.45 | 0.41 | 26.6 | 7.7 | 1.12 | .291 | 3.31 | 66 | 2.74 | 65 | 7.19 | 35.1 |
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