Pedro Strop has the lowest career ERA- for the Cubs when starting at most 10 games, pitching at least 300 innings with at most 30 saves, with an ERA- of 71.
| NAME | ERA- | IP | GS | SV | G | W | L | W% | ERA | SO | CG | SHO | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Strop | 71 | 375.0 | 0 | 29 | 413 | 22 | 24 | .478 | 2.88 | 428 | 0 | 0 | 246 | 120 | 131 | 26 | 149 | 29 | 95 | 15 | 1,522 | 36 | 10.27 | 3.58 | 2.87 | 0.62 | 28.1 | 9.8 | 1.05 | .247 | 3.14 | 3.18 | 79 | 5.90 | 35.2 |
| 2 | | D. Tidrow | 87 | 397.0 | 0 | 25 | 263 | 28 | 23 | .549 | 3.36 | 266 | 0 | 0 | 362 | 148 | 169 | 27 | 154 | 11 | 120 | 52 | 1,689 | 6 | 6.03 | 3.49 | 1.73 | 0.61 | 15.7 | 9.1 | 1.30 | .272 | 3.83 | 3.49 | 93 | 8.21 | 11.7 |
| 3 | | E. Kush | 94 | 346.1 | 8 | 12 | 150 | 21 | 12 | .636 | 3.48 | 150 | 2 | 1 | 324 | 134 | 146 | 21 | 158 | 10 | 78 | 1,481 | 8 | 3.90 | 4.11 | 0.95 | 0.55 | 10.1 | 10.7 | 1.39 | .265 | 3.79 | 3.87 | 104 | 8.42 | -7 | |
| 4 | | J. Russell | 103 | 306.0 | 5 | 4 | 365 | 10 | 18 | .357 | 4.03 | 223 | 0 | 0 | 310 | 137 | 161 | 41 | 91 | 9 | 62 | 21 | 1,307 | 6 | 6.56 | 2.68 | 2.45 | 1.21 | 17.1 | 7.0 | 1.31 | .285 | 4.74 | 4.34 | 112 | 9.12 | -15.5 |
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