Babe Ruth has the best career slugging percentage, with a slugging percentage of .690.

Interpreted as:

all-time highest slg with a minimum of 3000 PA by a player

	NAME	SLG	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	.690	10,617	2,503	8,399	2,174	2,873	506	136	714	2,214	2,062	43	1,330	123		5,793	1,356	113				.342	.474	1.164	2727	1,436.8	.513	197	1,369.6
2	Ted Williams T. Williams	.634	9,791	2,292	7,706	1,798	2,654	525	71	521	1,839	2,021	39	709	24	4	4,884	1,117	5	20	86	197	.344	.482	1.116	2349	1,219.7	.493	188	1,067
3	Lou Gehrig L. Gehrig	.632	9,660	2,164	8,001	1,888	2,721	534	163	493	1,995	1,508	45	790	102		5,060	1,190	106			2	.340	.447	1.080	2265	1,046.8	.477	173	980
4	Aaron Judge A. Judge	.613	4,807	1,104	3,966	830	1,160	197	7	353	804	773	37	1,337	60	19	2,430	557	0	31	96	112	.292	.410	1.023	1002	427.9	.423	176	431.5
5	Jimmie Foxx J. Foxx	.609	9,670	2,317	8,134	1,751	2,646	458	125	534	1,922	1,452	13	1,311	87		4,956	1,117	71			69	.325	.428	1.038	2135	934.1	.460	158	780.8
6	Barry Bonds B. Bonds	.607	12,606	2,986	9,847	2,227	2,935	601	77	762	1,996	2,558	106	1,539	514	141	5,976	1,440	4	91	688	165	.298	.444	1.051	2663	1,143.3	.435	172	1,142
7	Hank Greenberg H. Greenberg	.605	6,096	1,394	5,193	1,046	1,628	379	71	331	1,274	852	16	844	58		3,142	781	35			66	.313	.412	1.017	1287	556.1	.453	154	446.7
8	Mark McGwire M. McGwire	.588	7,660	1,874	6,187	1,167	1,626	252	6	583	1,414	1,317	75	1,596	12	8	3,639	841	3	78	150	147	.263	.394	.982	1480	564.9	.415	157	558.2
9	Manny Ramirez M. Ramirez	.585	9,774	2,302	8,244	1,544	2,574	547	20	555	1,831	1,329	109	1,813	38	33	4,826	1,122	2	90	216	243	.312	.411	.996	1931	719.5	.418	153	658.7
10	Shohei Ohtani S. Ohtani	.582	4,141	979	3,584	677	1,010	183	44	268	646	512	25	1,065	162	42	2,085	495	0	20	84	46	.282	.374	.955	772	278.2	.396	156	274.3
11	Joe DiMaggio J. DiMaggio	.579	7,671	1,736	6,821	1,390	2,214	389	131	361	1,537	790	46	369	30	0	3,948	881	14			130	.325	.398	.977	1517	604.1	.439	152	528.8
12	Rogers Hornsby R. Hornsby	.577	9,475	2,259	8,173	1,579	2,930	541	169	301	1,584	1,038	48	679	135		4,712	1,011	216				.358	.434	1.010	2018	899	.459	173	863.2
13	Mike Trout M. Trout	.574	7,047	1,611	5,838	1,175	1,726	320	55	398	1,006	1,044	105	1,606	214	38	3,350	773	0	60	130	73	.296	.408	.982	1372	553.7	.412	167	555.2
14	Larry Walker L. Walker	.565	8,030	1,988	6,907	1,355	2,160	471	62	383	1,311	913	138	1,231	230	76	3,904	916	7	65	117	153	.313	.400	.965	1532	556.6	.412	140	406.2
15	Albert Belle A. Belle	.564	6,673	1,539	5,853	974	1,726	389	21	381	1,239	683	55	961	88	41	3,300	791	4	78	91	193	.295	.369	.933	1184	366.5	.396	139	338.6
16	Johnny Mize J. Mize	.562	7,371	1,884	6,443	1,118	2,011	367	83	359	1,337	856	52	524	28	0	3,621	809	20			76	.312	.397	.959	1421	546.3	.433	157	508.1
17	Juan Gonzalez J. Gonzalez	.561	7,155	1,689	6,556	1,061	1,936	388	25	434	1,404	457	62	1,273	26	19	3,676	847	2	78	74	184	.295	.343	.904	1190	314.6	.383	129	264.9
18	Stan Musial S. Musial	.559	12,712	3,026	10,972	1,949	3,630	725	177	475	1,951	1,599	53	696	78	31	6,134	1,377	35	53	127	243	.331	.417	.976	2474	1,032.5	.435	158	896.7
19	Willie Mays W. Mays	.557	12,493	2,992	10,881	2,062	3,283	523	140	660	1,903	1,464	44	1,526	338	103	6,066	1,323	13	91	192	251	.302	.384	.941	2266	894.8	.409	154	802.7
20	Mickey Mantle M. Mantle	.557	9,909	2,401	8,102	1,676	2,415	344	72	536	1,509	1,733	13	1,710	153	38	4,511	952	14	47	126	113	.298	.421	.977	1941	840	.428	170	821.8
21	Frank Thomas F. Thomas	.555	10,074	2,322	8,199	1,494	2,468	495	12	521	1,704	1,667	87	1,397	32	23	4,550	1,028	0	121	168	226	.301	.419	.974	1954	721.1	.416	154	692
22	Hank Aaron H. Aaron	.555	13,940	3,298	12,364	2,174	3,771	624	98	755	2,297	1,402	32	1,383	240	73	6,856	1,477	21	121	293	328	.305	.374	.928	2453	936.4	.403	153	858.5
23	Jim Thome J. Thome	.554	10,313	2,543	8,422	1,583	2,328	451	26	612	1,699	1,747	69	2,548	19	20	4,667	1,089	1	74	173	165	.276	.402	.956	1925	653.9	.406	145	589.5
24	Vladimir Guerrero V. Guerrero	.553	9,059	2,147	8,155	1,328	2,590	477	46	449	1,496	737	103	985	181	94	4,506	972	0	64	250	277	.318	.379	.931	1575	464.6	.390	136	419
25	David Ortiz D. Ortiz	.552	10,091	2,408	8,640	1,419	2,472	632	19	541	1,768	1,319	38	1,750	17	9	4,765	1,192	2	92	209	236	.286	.380	.931	1760	559.9	.392	140	484.1