Babe Ruth has the most career home runs per plate appearance when making 10,000+ plate appearances, with 0.07.

	NAME	HR/PA	PA	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	0.07	10,617	714	2,503	8,399	2,174	2,873	506	136	2,214	2,062	43	1,330	123		5,793	1,356	113				.342	.474	.690	1.164	2727	1,436.8	.513	197	1,369.6
2	Barry Bonds B. Bonds	0.06	12,606	762	2,986	9,847	2,227	2,935	601	77	1,996	2,558	106	1,539	514	141	5,976	1,440	4	91	688	165	.298	.444	.607	1.051	2663	1,143.3	.435	172	1,142
3	Jim Thome J. Thome	0.06	10,313	612	2,543	8,422	1,583	2,328	451	26	1,699	1,747	69	2,548	19	20	4,667	1,089	1	74	173	165	.276	.402	.554	.956	1925	653.9	.406	145	589.5
4	Alex Rodriguez A. Rodriguez	0.06	12,207	696	2,784	10,566	2,021	3,115	548	31	2,086	1,338	176	2,287	329	76	5,813	1,275	16	111	97	261	.295	.380	.550	.930	2178	690.1	.395	141	629.5
5	Ken Griffey Jr. K. Griffey Jr.	0.06	11,304	630	2,671	9,801	1,662	2,781	524	38	1,836	1,312	81	1,779	184	69	5,271	1,192	8	102	246	199	.284	.370	.538	.907	1892	521.1	.384	132	453.4
6	Mike Schmidt M. Schmidt	0.05	10,062	548	2,404	8,352	1,506	2,234	408	59	1,595	1,507	79	1,883	174	92	4,404	1,015	16	108	201	156	.267	.380	.527	.908	1717	591	.395	147	539.8
7	Hank Aaron H. Aaron	0.05	13,940	755	3,298	12,364	2,174	3,771	624	98	2,297	1,402	32	1,383	240	73	6,856	1,477	21	121	293	328	.305	.374	.555	.928	2453	936.4	.403	153	858.5
8	Albert Pujols A. Pujols	0.05	13,041	703	3,080	11,421	1,914	3,384	686	16	2,218	1,373	123	1,404	117	43	6,211	1,405	1	123	316	426	.296	.374	.544	.918	2233	685	.385	141	673
9	David Ortiz D. Ortiz	0.05	10,091	541	2,408	8,640	1,419	2,472	632	19	1,768	1,319	38	1,750	17	9	4,765	1,192	2	92	209	236	.286	.380	.552	.931	1760	559.9	.392	140	484.1
10	Willie Mays W. Mays	0.05	12,493	660	2,992	10,881	2,062	3,283	523	140	1,903	1,464	44	1,526	338	103	6,066	1,323	13	91	192	251	.302	.384	.557	.941	2266	894.8	.409	154	802.7
11	Frank Thomas F. Thomas	0.05	10,074	521	2,322	8,199	1,494	2,468	495	12	1,704	1,667	87	1,397	32	23	4,550	1,028	0	121	168	226	.301	.419	.555	.974	1954	721.1	.416	154	692
12	Eddie Mathews E. Mathews	0.05	10,101	512	2,391	8,537	1,509	2,315	354	72	1,453	1,444	26	1,487	68	39	4,349	938	36	58	107	123	.271	.376	.509	.885	1685	557.5	.389	143	531.2
13	Frank Robinson F. Robinson	0.05	11,743	586	2,808	10,006	1,829	2,943	528	72	1,812	1,420	198	1,532	204	77	5,373	1,186	17	102	218	270	.294	.389	.537	.926	2083	807.2	.404	153	717.1
14	Reggie Jackson R. Jackson	0.05	11,416	563	2,820	9,864	1,551	2,584	463	49	1,702	1,375	96	2,597	228	115	4,834	1,075	13	68	164	183	.262	.356	.490	.846	1749	503	.374	139	497.6
15	Ernie Banks E. Banks	0.05	10,395	512	2,528	9,421	1,305	2,583	407	90	1,636	763	70	1,236	50	53	4,706	1,009	45	96	198	229	.274	.330	.500	.830	1496	354.6	.359	118	228.9
16	Fred McGriff F. McGriff	0.05	10,174	493	2,460	8,757	1,349	2,490	441	24	1,550	1,305	39	1,882	72	38	4,458	958	2	71	171	226	.284	.377	.509	.886	1678	454.1	.383	134	415.9
17	Rafael Palmeiro R. Palmeiro	0.05	12,046	569	2,831	10,472	1,663	3,020	585	38	1,835	1,353	87	1,348	97	40	5,388	1,192	15	119	172	232	.288	.371	.515	.885	1975	522.8	.380	130	453.5
18	Gary Sheffield G. Sheffield	0.05	10,947	509	2,576	9,217	1,636	2,689	467	27	1,676	1,475	135	1,171	253	104	4,737	1,003	9	111	130	235	.292	.393	.514	.907	1907	574.5	.391	141	567.2
19	Mel Ott M. Ott	0.05	11,337	511	2,730	9,456	1,859	2,876	488	72	1,860	1,708	64	896	89		5,041	1,071	109			38	.304	.414	.533	.947	2204	826.4	.430	156	794.2
20	Chipper Jones C. Jones	0.04	10,614	468	2,499	8,984	1,619	2,726	549	38	1,623	1,512	18	1,409	150	46	4,755	1,055	3	97	177	253	.303	.401	.529	.930	1904	598.1	.397	141	563
21	Miguel Cabrera M. Cabrera	0.04	11,796	511	2,797	10,356	1,551	3,174	627	17	1,881	1,258	74	2,105	40	21	5,368	1,155	5	103	238	364	.306	.382	.518	.901	1981	585.3	.382	139	547.8
22	Andre Dawson A. Dawson	0.04	10,769	438	2,627	9,927	1,373	2,774	503	98	1,591	589	111	1,509	314	109	4,787	1,039	24	118	143	217	.279	.323	.482	.806	1471	247.5	.350	117	211.8
23	Billy Williams B. Williams	0.04	10,519	426	2,488	9,350	1,410	2,711	434	88	1,475	1,045	43	1,046	90	49	4,599	948	8	73	182	200	.290	.361	.492	.853	1630	511.5	.376	132	377.3
24	Carlos Beltran C. Beltran	0.04	11,031	435	2,586	9,768	1,582	2,725	565	78	1,587	1,084	51	1,795	312	49	4,751	1,078	18	110	104	203	.279	.350	.486	.837	1621	297.8	.358	118	246.4
25	Adrian Beltre A. Beltre	0.04	12,130	477	2,933	11,068	1,524	3,166	636	38	1,707	848	97	1,732	121	42	5,309	1,151	14	103	112	279	.286	.339	.480	.819	1705	256.1	.350	115	216.7