Roger Clemens has the most career runs above average, with 680.4.

	NAME	PRAA	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9
1	Roger Clemens R. Clemens	680.4	709	354	184	.658	707	3.12	4,672	118	46	0	4916.2	4,185	1,707	1,885	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	70	3.08	71	7.66
2	Cy Young C. Young	620	906	511	316	.618	815	2.63	2,803	749	76	17	7356.0	7,092	2,147	3,167	138	1,217	161	84		29,565	156	3.43	1.49	2.30	0.17	9.5	4.1	1.13	.275	3.87	74	2.84	79	8.68
3	Randy Johnson R. Johnson	554.3	618	303	166	.646	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28
4	Greg Maddux G. Maddux	519.5	744	355	227	.610	740	3.16	3,371	109	35	0	5008.1	4,726	1,756	1,981	353	999	137	3	177	20,421	70	6.06	1.80	3.37	0.63	16.5	4.9	1.14	.281	3.56	76	3.25	78	8.49
5	Walter Johnson W. Johnson	472.8	802	417	279	.599	666	2.17	3,509	531	110	34	5914.1	4,913	1,424	1,902	97	1,363	205	127		23,405	154	5.34	2.07	2.57	0.15	15.0	5.8	1.06	.264	2.89	68	2.42	76	7.48
6	Lefty Grove L. Grove	462.8	616	300	141	.680	457	3.06	2,266	298	35	54	3940.2	3,849	1,339	1,594	162	1,187	42	123		16,622	51	5.18	2.71	1.91	0.37	13.6	7.1	1.28	.284	3.64	68	3.36	76	8.79
7	Pedro Martinez P. Martinez	454.6	476	219	100	.687	409	2.93	3,154	46	17	3	2827.1	2,221	919	1,006	239	760	141	23	30	11,394	62	10.04	2.42	4.15	0.76	27.7	6.7	1.05	.279	3.20	66	2.91	68	7.07
8	Kid Nichols K. Nichols	377.8	621	361	208	.634	562	2.96	1,881	532	48	17	5067.1	4,929	1,664	2,480	156	1,272	129	56		21,082	169	3.34	2.26	1.48	0.28	8.9	6.0	1.22	.271	4.40	73	3.48	85	8.75
9	Curt Schilling C. Schilling	373.6	569	216	146	.597	436	3.46	3,116	83	20	22	3261.0	2,998	1,253	1,318	347	711	52	81	43	13,284	72	8.60	1.96	4.38	0.96	23.5	5.4	1.14	.293	3.64	80	3.22	76	8.27
10	Mike Mussina M. Mussina	372.8	537	270	153	.638	536	3.68	2,813	57	23	0	3562.2	3,460	1,458	1,559	376	785	60	0	29	14,593	71	7.11	1.98	3.58	0.95	19.3	5.4	1.19	.292	3.94	82	3.57	79	8.74
11	Nolan Ryan N. Ryan	370.2	807	324	292	.526	773	3.19	5,714	222	61	3	5386.0	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56
12	Clayton Kershaw C. Kershaw	369.5	447	219	96	.695	444	2.51	3,017	25	15	0	2820.1	2,164	788	865	234	698	46	1	28	11,132	107	9.63	2.23	4.32	0.75	27.1	6.3	1.01	.270	2.76	64	2.85	70	6.91
13	Bert Blyleven B. Blyleven	368.6	692	287	250	.534	685	3.31	3,701	242	60	0	4970.0	4,632	1,830	2,029	430	1,322	155	3	71	20,491	114	6.70	2.39	2.80	0.78	18.1	6.5	1.20	.282	3.67	85	3.18	82	8.39
14	Christy Mathewson C. Mathewson	363	636	373	188	.665	552	2.13	2,507	435	79	30	4788.2	4,219	1,135	1,620	89	848	59	73		18,913	115	4.71	1.59	2.96	0.17	13.3	4.5	1.06	.268	3.04	75	2.26	76	7.93
15	Grover Alexander G. Alexander	359.1	696	373	208	.642	600	2.56	2,198	436	90	32	5190.0	4,868	1,476	1,852	165	951	70	81		20,893	38	3.81	1.65	2.31	0.29	10.5	4.6	1.12	.269	3.21	73	2.88	81	8.44
16	John Smoltz J. Smoltz	356.6	723	213	155	.579	481	3.33	3,084	53	16	154	3473.0	3,074	1,284	1,391	288	1,010	57	204	84	14,271	145	7.99	2.62	3.05	0.75	21.6	7.1	1.18	.283	3.60	81	3.23	78	7.97
17	Kevin Brown K. Brown	344.2	486	211	144	.594	476	3.28	2,397	72	17	0	3256.1	3,079	1,185	1,357	208	901	139	1	42	13,542	108	6.62	2.49	2.66	0.57	17.7	6.7	1.22	.290	3.75	78	3.32	78	8.51
18	Gaylord Perry G. Perry	312.9	777	314	265	.542	690	3.11	3,534	303	53	10	5350.0	4,938	1,846	2,128	399	1,379	108	33	164	21,953	160	5.95	2.32	2.56	0.67	16.1	6.3	1.18	.275	3.58	85	3.06	85	8.31
19	Justin Verlander J. Verlander	308.5	547	263	156	.628	547	3.33	3,511	26	9	0	3522.0	3,006	1,302	1,410	367	988	120	0	27	14,413	99	8.97	2.52	3.55	0.94	24.4	6.9	1.13	.280	3.60	79	3.43	81	7.68
20	Max Scherzer M. Scherzer	307.6	476	218	114	.657	467	3.17	3,459	12	5	0	2932.0	2,392	1,033	1,106	346	768	114	2	20	11,845	79	10.62	2.36	4.50	1.06	29.2	6.5	1.08	.286	3.39	76	3.20	77	7.34
21	Chris Sale C. Sale	297.2	387	143	87	.622	307	3.02	2,528	16	3	12	2047.2	1,668	686	739	209	481	126	25	15	8,249	47	11.11	2.11	5.26	0.92	30.6	5.8	1.05	.297	3.25	71	2.88	69	7.33
22	Roy Halladay R. Halladay	296	416	203	105	.659	390	3.38	2,117	67	20	1	2749.1	2,646	1,034	1,135	236	592	81	6	28	11,287	56	6.93	1.94	3.58	0.77	18.8	5.2	1.18	.292	3.72	77	3.39	77	8.66
23	Bob Gibson B. Gibson	290.5	528	251	174	.591	482	2.91	3,117	255	56	6	3884.1	3,279	1,258	1,420	257	1,336	102	21	118	16,068	108	7.22	3.10	2.33	0.60	19.4	8.3	1.19	.268	3.29	78	2.89	81	7.60
24	John Clarkson J. Clarkson	289.8	531	328	178	.648	518	2.81	1,978	485	37	5	4536.1	4,295	1,417	2,384	159	1,191	80	12		19,146	182	3.92	2.36	1.66	0.32	10.3	6.2	1.21	.263	4.73	75	3.35	88	8.52
25	Dazzy Vance D. Vance	288.3	442	197	140	.585	349	3.24	2,045	217	29	12	2966.2	2,809	1,068	1,246	132	840	77	52		12,366	37	6.20	2.55	2.43	0.40	16.5	6.8	1.23	.289	3.78	81	3.18	79	8.52