Lou Gehrig has the highest career slugging percentage when making 400+ plate appearances in the month of June, with a slugging percentage of .739.

Interpreted as:

highest career slg by a player in june with 400+ pa

	NAME	SLG	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	OPS
1	Lou Gehrig L. Gehrig	.739	1,752	383	1,484	405	561	112	36	117	386	249	7	148	29		1,096	265	12				.378	.470	1.208
2	Shohei Ohtani S. Ohtani	.721	673	157	569	120	181	33	8	60	129	93	4	164	16	5	410	101	0	7	13	9	.318	.413	1.134
3	Babe Ruth B. Ruth	.710	1,937	454	1,499	407	529	78	17	141	413	416	14	257	25		1,064	236	8				.353	.497	1.207
4	Yordan Alvarez Y. Alvarez	.675	414	98	351	78	116	21	2	32	99	53	8	74	2	1	237	55	0	2	5	14	.330	.428	1.103
5	Larry Walker L. Walker	.641	1,320	326	1,111	248	376	77	8	81	243	162	31	195	31	20	712	166	0	16	22	22	.338	.431	1.072
6	Ted Williams T. Williams	.635	1,895	433	1,501	367	504	114	19	99	378	380	9	144	4	1	953	232	0	5	15	35	.336	.471	1.106
7	Hank Greenberg H. Greenberg	.621	1,108	248	953	190	299	72	16	63	239	143	2	164	11		592	151	10			9	.314	.404	1.026
8	Jim Thome J. Thome	.616	1,735	441	1,408	281	394	79	5	128	314	302	13	427	6	2	867	212	0	12	25	27	.280	.409	1.024
9	Jimmie Foxx J. Foxx	.615	1,891	454	1,601	364	526	84	21	111	388	277	1	259	21		985	216	12			12	.329	.428	1.043
10	Aaron Judge A. Judge	.606	715	161	596	131	173	25	2	53	129	111	5	207	10	1	361	80	0	3	18	11	.290	.404	1.010
11	Ronald Acuña Jr. R. Acuña Jr.	.604	574	123	492	121	160	29	0	36	78	69	10	119	38	11	297	65	0	3	2	6	.325	.416	1.020
12	Rogers Hornsby R. Hornsby	.603	1,738	407	1,490	287	527	89	36	70		210	12	130	33		898	195	26				.354	.438	1.040
13	Fernando Tatis Jr. F. Tatis Jr.	.600	504	115	435	103	140	31	3	28	68	59	8	113	26	3	261	62	1	1	1	5	.322	.412	1.012
14	Frank Thomas F. Thomas	.592	1,706	395	1,396	268	429	73	2	107	298	276	18	256	7	6	827	182	0	16	35	40	.307	.424	1.016
15	Mike Piazza M. Piazza	.591	1,313	318	1,184	203	382	61	1	85	237	118	4	171	3	3	700	147	0	7	27	34	.323	.384	.975
16	Joe DiMaggio J. DiMaggio	.585	1,429	323	1,288	265	399	74	23	78	276	129	9	72	3	0	753	175	3			29	.310	.377	.961
17	Kevin Mitchell K. Mitchell	.583	752	200	662	117	215	52	4	37	126	82	2	81	5	0	386	93	0	6	20	13	.325	.398	.981
18	Mike Trout M. Trout	.580	1,128	255	942	184	301	55	8	58	156	164	14	241	38	4	546	121	0	8	24	12	.320	.425	1.004
19	Stan Musial S. Musial	.579	2,275	538	1,951	350	652	116	41	93	352	299	11	102	12	6	1,129	250	9	5	27	49	.334	.425	1.003
20	Randy Milligan R. Milligan	.578	483	130	400	69	128	22	0	27	82	80	2	68	2	4	231	49	0	1	2	12	.320	.435	1.012
21	Mark McGwire M. McGwire	.576	1,423	346	1,156	209	299	42	2	107	249	237	14	315	2	2	666	151	1	15	28	25	.259	.387	.963
22	Ketel Marte K. Marte	.576	786	188	693	153	231	50	5	36	109	86	3	107	9	4	399	91	1	3	7	16	.333	.408	.983
23	Chuck Klein C. Klein	.575	1,362	321	1,237	231	414	74	17	63	241	114	3	88	10		711	154	8			6	.335	.392	.967
24	Bernie Williams B. Williams	.573	1,312	301	1,136	221	376	82	8	59	218	160	5	165	22	12	651	149	0	11	11	31	.331	.412	.985
25	Dante Bichette D. Bichette	.573	1,252	303	1,187	196	383	97	7	62	235	51	2	192	28	13	680	166	0	12	5	32	.323	.348	.921