Andy Larkin has the highest career ERA when pitching at least 100 innings, with an ERA of 8.86.

Interpreted as:

highest era by a player with 100 or more ip all-time

	NAME	ERA	IP	G	W	L	W%	GS	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Andy Larkin A. Larkin	8.86	105.2	39	3	11	.214	15	69	0	0	1	139	104	112	18	75	5	11	5	522	5	5.88	6.39	0.92	1.53	13.2	14.4	2.03	.341	9.54	208	6.31	144	11.84	-22.8
2	Dewey McDougal D. McDougal	8.30	124.2	21	3	11	.214	15	23	10	0	0	200	115	157	13	50	11	6		622	1	1.66	3.61	0.46	0.94	3.7	8.0	2.01	.356	11.33	177	6.01	128	14.44	-18.5
3	Aaron Myette A. Myette	8.16	154.1	47	6	12	.333	30	134	0	0	0	185	140	144	26	106	22	7	1	761	9	7.81	6.18	1.26	1.52	17.6	13.9	1.89	.336	8.40	174	5.97	131	10.79	-23.2
4	Connor Seabold C. Seabold	7.73	115.1	36	1	11	.083	19	91	0	0	0	161	99	103	25	41	10	10	1	547	9	7.10	3.20	2.22	1.95	16.6	7.5	1.75	.358	8.04	164	5.78	130	12.56	-16.2
5	Mark Holzemer M. Holzemer	7.69	100.2	94	2	5	.286	4	64	0	0	1	138	86	93	15	47	9	24	3	490	4	5.72	4.20	1.36	1.34	13.1	9.6	1.84	.346	8.31	166	5.43	116	12.34	-8.6
6	William Rotes W. Rotes	7.60	151.2	20	5	12	.294	19	22	17	0	0	244	128	173	10	66	10	1		769	1	1.31	3.92	0.33	0.59	2.9	8.6	2.04	.354	10.27	170	5.31	119	14.48	-16.2
7	David Wainhouse D. Wainhouse	7.37	105.0	85	2	3	.400	0	66	0	0	0	130	86	91	15	61	8	31	2	498	8	5.66	5.23	1.08	1.29	13.3	12.2	1.82	.330	7.80	159	5.69	125	11.14	-12.4
8	Ryan Feierabend R. Feierabend	7.34	119.0	33	2	12	.143	20	72	1	0	0	170	97	97	22	47	5	3	3	557	7	5.45	3.55	1.53	1.66	12.9	8.4	1.82	.360	7.34	171	5.68	132	12.86	-18.7
9	Chet Nichols C. Nichols	7.19	122.2	44	1	8	.111	5	33	1	0	1	167	98	116	11	56	4	13		591	3	2.42	4.11	0.59	0.81	5.6	9.5	1.82	.320	8.51	154	5.35	112	12.25	-6
10	Luther Roy L. Roy	7.17	170.2	56	6	13	.316	17	36	3	0	0	231	136	157	14	92	4	20		824	6	1.90	4.85	0.39	0.74	4.4	11.2	1.89	.320	8.28	152	5.44	120	12.18	-15.6
11	Laurin Pepper L. Pepper	7.06	109.2	44	2	8	.200	17	40	0	0	0	134	86	102	11	98	2	13	3	551	6	3.28	8.04	0.41	0.90	7.3	17.8	2.12	.308	8.37	175	5.70	142	11.00	-20.5
12	Jake Boyd J. Boyd	7.02	143.2	22	3	16	.158	18	27	13	0	0	214	112	164	2	69	17	4		716	5	1.69	4.32	0.39	0.13	3.8	9.6	1.97	.353	10.27	148	5.15	109	13.41	-6.8
13	Greg Reynolds G. Reynolds	7.01	123.1	33	6	11	.353	21	53	0	0	0	161	96	99	25	42	9	3	6	571	3	3.87	3.06	1.26	1.82	9.3	7.4	1.65	.308	7.22	159	6.09	143	11.75	-24.1
14	Spencer Howard S. Howard	7.00	144.0	47	4	13	.235	32	136	0	0	0	181	112	123	31	69	6	5	1	683	7	8.50	4.31	1.97	1.94	19.9	10.1	1.74	.340	7.69	168	5.62	134	11.31	-21.9
15	Bill Kissinger B. Kissinger	6.99	319.1	53	7	25	.219	32	61	23	0	1	500	248	342	15	123	24	20		1,568	10	1.72	3.47	0.50	0.42	3.9	7.8	1.95	.361	9.64	154	5.04	111	14.09	-17
16	Hal Elliott H. Elliott	6.95	322.1	120	11	24	.314	30	90	4	0	3	453	249	295	22	174	2	42		1,550	4	2.51	4.86	0.52	0.61	5.8	11.2	1.95	.342	8.24	140	5.22	106	12.65	-5.2
17	Carl Doyle C. Doyle	6.95	222.2	51	6	15	.286	21	101	6	1	2	277	172	195	18	155	17	16		1,099	16	4.08	6.26	0.65	0.73	9.2	14.1	1.94	.321	7.88	159	5.46	126	11.20	-27
18	Hector Fajardo H. Fajardo	6.95	124.1	30	5	9	.357	17	78	0	0	0	149	96	100	19	42	4	3	0	558	10	5.65	3.04	1.86	1.38	14.0	7.5	1.54	.313	7.24	149	4.91	107	10.79	-4.8
19	Radhames Liz R. Liz	6.94	133.2	42	7	12	.368	21	109	0	0	0	158	103	109	24	88	9	12	6	637	10	7.34	5.93	1.24	1.62	17.1	13.8	1.84	.329	7.34	158	6.02	137	10.64	-23.5
20	Scott Klingenbeck S. Klingenbeck	6.91	138.0	39	5	8	.385	17	75	0	0	0	175	106	114	34	63	7	6	1	643	8	4.89	4.11	1.19	2.22	11.7	9.8	1.72	.304	7.43	145	6.76	144	11.41	-31.4
21	Chris Fussell C. Fussell	6.90	135.2	40	5	9	.357	19	91	0	0	2	159	104	112	28	89	7	5	6	632	9	6.04	5.90	1.02	1.86	14.4	14.1	1.83	.314	7.43	136	6.59	134	10.55	-24.6
22	Jack Wadsworth J. Wadsworth	6.85	367.2	47	6	38	.136	44	87	39	0	0	524	280	393	16	199	10	2		1,808	32	2.13	4.87	0.44	0.39	4.8	11.0	1.97	.340	9.62	156	5.17	116	12.83	-30.3
23	Mike Johnson M. Johnson	6.85	218.0	81	7	14	.333	32	147	0	0	2	254	166	169	47	103	13	10	6	1,003	17	6.07	4.25	1.43	1.94	14.7	10.3	1.64	.299	6.98	153	6.16	136	10.49	-39.6
24	Jack Knight J. Knight	6.85	255.0	72	10	18	.357	27	49	9	0	5	382	194	231	27	89	1	26		1,214	4	1.73	3.14	0.55	0.95	4.0	7.3	1.85	.339	8.15	157	5.05	115	13.48	-15.4
25	Zach Stewart Z. Stewart	6.82	103.0	33	3	10	.231	14	64	1	1	0	148	78	84	25	22	3	9	2	465	2	5.59	1.92	2.91	2.18	13.8	4.7	1.65	.350	7.34	161	5.68	135	12.93	-16.1