Barry Bonds has the most home runs per at-bat with 100+ games played in a season, with 0.15 in 2001.

Interpreted as:

highest hr/ab by a player in a season (min 100 g)

	NAME	HR/AB	G	HR	AB	SEASON	TM	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Barry Bonds B. Bonds	0.15	153	73	476	2001	SFG	129	156	32	2	137	177	9	93	13	3	664	411	107	0	2	35	5	.328	.515	.863	1.379	200	117.7	.537	234	116.6
2	Mark McGwire M. McGwire	0.14	155	70	509	1998	STL	130	152	21	0	147	162	6	155	1	0	681	383	91	0	4	28	8	.299	.470	.752	1.222	176	91.7	.492	205	90.7
3	Mark McGwire M. McGwire	0.12	153	65	521	1999	STL	118	145	21	1	147	133	2	141	0	0	661	363	87	0	5	21	12	.278	.424	.697	1.120	150	64.2	.453	169	61.5
4	Mark McGwire M. McGwire	0.12	104	39	317	1995	OAK	75	87	13	0	90	88	11	77	1	1	422	217	52	0	6	5	9	.274	.441	.685	1.125	99	46.7	.466	183	45.9
5	Mark McGwire M. McGwire	0.12	130	52	423	1996	OAK	104	132	21	0	113	116	8	112	0	0	548	309	73	0	1	16	14	.312	.467	.730	1.198	142	71.8	.489	190	68.5
6	Barry Bonds B. Bonds	0.12	147	45	373	2004	SFG	129	135	27	3	101	232	9	41	6	1	617	303	75	0	3	120	5	.362	.609	.812	1.422	185	108	.537	233	105.7
7	Babe Ruth B. Ruth	0.12	142	54	458	1920	NYY	158	172	36	9	135	150	3	80	14	14	616	388	99	5				.376	.532	.847	1.379	191	120.9	.597	237	110.5
8	Barry Bonds B. Bonds	0.12	130	45	390	2003	SFG	111	133	22	1	90	148	10	58	7	0	550	292	68	0	2	61	7	.341	.529	.749	1.278	148	80.5	.503	212	79.4
9	Barry Bonds B. Bonds	0.11	143	46	403	2002	SFG	117	149	31	2	110	198	9	47	9	2	612	322	79	0	2	68	4	.370	.582	.799	1.381	183	110	.544	244	109.9
10	Babe Ruth B. Ruth	0.11	151	60	540	1927	NYY	158	192	29	8	165	137	0	89	7	6	691	417	97	14				.356	.486	.772	1.258	195	109.9	.545	212	104.8
11	Sammy Sosa S. Sosa	0.11	160	64	577	2001	CHC	146	189	34	5	160	116	6	153	0	2	711	425	103	0	12	37	6	.328	.437	.737	1.174	171	82.7	.465	186	79.8
12	Babe Ruth B. Ruth	0.11	152	59	540	1921	NYY	177	204	44	16	168	145	4	81	17	13	693	457	119	4				.378	.512	.846	1.359	214	127.8	.575	224	118.7
13	Aaron Judge A. Judge	0.11	157	62	570	2022	NYY	133	177	28	0	131	111	6	175	16	3	692	391	90	0	5	19	14	.311	.425	.686	1.111	161	81.6	.458	208	84.5
14	Jim Thome J. Thome	0.11	147	52	480	2002	CLE	101	146	19	2	118	122	5	139	1	2	613	325	73	0	6	18	5	.304	.445	.677	1.122	142	68.3	.461	189	67.1
15	Mark McGwire M. McGwire	0.11	156	58	540	1997	TOT	86	148	27	0	123	101	9	159	3	0	657	349	85	0	7	16	9	.274	.393	.646	1.039	134	52.9	.429	161	51.4
16	Mickey Mantle M. Mantle	0.11	153	54	514	1961	NYY	131	163	16	6	128	126	0	112	12	1	646	353	76	1	5	9	2	.317	.448	.687	1.135	156	79.6	.478	197	78.8
17	Hank Greenberg H. Greenberg	0.1	155	58	556	1938	DET	143	175	23	4	147	119	3	92	7	5	681	380	85	3				.315	.438	.683	1.122	166	80.3	.489	162	62
18	J.D. Martinez	0.1	119	45	432	2017	TOT	85	131	26	3	104	53	0	128	4	0	489	298	74	0	4	8	23	.303	.376	.690	1.066	105	45.1	.430	167	41.2
19	Aaron Judge A. Judge	0.1	158	58	559	2024	NYY	122	180	36	1	144	133	9	171	10	0	703	392	95	0	2	20	22	.322	.458	.701	1.159	176	93.7	.476	219	95.5
20	Roger Maris R. Maris	0.1	161	61	590	1961	NYY	132	159	16	4	141	94	7	67	0	0	698	366	81	0	7	0	16	.269	.372	.620	.993	138	55.9	.424	162	55.1
21	Sammy Sosa S. Sosa	0.1	159	66	643	1998	CHC	134	198	20	0	158	73	1	171	18	9	722	416	86	0	5	14	20	.308	.377	.647	1.024	146	56.6	.425	159	53.7
22	Barry Bonds B. Bonds	0.1	143	49	480	2000	SFG	129	147	28	4	106	117	3	77	11	3	607	330	81	0	7	22	6	.306	.440	.688	1.127	141	61	.456	174	61.2
23	Hank Aaron H. Aaron	0.1	120	40	392	1973	ATL	84	118	12	1	96	68	1	51	1	1	465	252	53	0	4	13	7	.301	.402	.643	1.045	97	46	.449	176	40.8
24	Aaron Judge A. Judge	0.1	106	37	367	2023	NYY	79	98	16	0	75	88	0	130	3	1	458	225	53	0	3	9	5	.267	.406	.613	1.019	95	38.8	.420	172	39.7
25	Sammy Sosa S. Sosa	0.1	162	63	625	1999	CHC	114	180	24	2	141	78	3	171	7	8	712	397	89	0	6	8	17	.288	.367	.635	1.002	138	45.2	.414	143	41.3