Chris Sale has the highest career K/9, with 11.14 per nine innings.

Interpreted as:

highest k/9 with a minimum of 1500 IP of all-time pitchers

	NAME	K/9	IP	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Chris Sale C. Sale	11.14	2084.0	393	145	88	.622	312	3.01	2,579	16	3	12	1,692	697	750	213	487	130	25	15	8,389	48	2.10	5.30	0.92	30.7	5.8	1.05	.297	3.24	70	2.87	68	7.31	303.3
2	Jacob deGrom J. deGrom	10.82	1539.2	248	96	65	.596	248	2.57	1,851	4	2	0	1,173	440	477	146	345	25	0	13	6,045	30	2.02	5.37	0.85	30.6	5.7	0.99	.279	2.79	66	2.70	66	6.86	239.4
3	Randy Johnson R. Johnson	10.61	4135.1	618	303	166	.646	603	3.29	4,875	100	37	2	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
4	Max Scherzer M. Scherzer	10.60	2963.0	483	220	117	.653	474	3.22	3,489	12	5	0	2,433	1,059	1,132	354	779	114	2	20	11,987	80	2.37	4.48	1.08	29.1	6.5	1.08	.287	3.44	77	3.23	78	7.39	302.5
5	Yu Darvish Y. Darvish	10.50	1778.0	297	115	93	.553	297	3.65	2,075	2	1	0	1,460	721	756	231	563	83	0	8	7,305	83	2.85	3.69	1.17	28.4	7.7	1.14	.282	3.83	87	3.58	85	7.39	120
6	Gerrit Cole G. Cole	10.37	1954.0	317	153	80	.657	317	3.18	2,251	8	5	0	1,627	690	740	217	500	61	0	8	7,861	58	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
7	Pedro Martinez P. Martinez	10.04	2827.1	476	219	100	.687	409	2.93	3,154	46	17	3	2,221	919	1,006	239	760	141	23	30	11,394	62	2.42	4.15	0.76	27.7	6.7	1.05	.279	3.20	66	2.91	68	7.07	454.6
8	Aaron Nola A. Nola	9.84	1715.2	285	109	89	.551	285	3.83	1,876	6	4	0	1,522	730	769	217	449	56	0	16	7,039	18	2.36	4.18	1.14	26.7	6.4	1.15	.294	4.03	91	3.50	82	7.98	147.1
9	Clayton Kershaw C. Kershaw	9.62	2855.1	455	223	96	.699	451	2.53	3,052	25	15	0	2,193	804	881	235	713	46	1	28	11,279	108	2.25	4.28	0.74	27.1	6.3	1.02	.271	2.78	65	2.85	70	6.91	375.1
10	Nolan Ryan N. Ryan	9.55	5386.0	807	324	292	.526	773	3.19	5,714	222	61	3	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56	370.2
11	Zack Wheeler Z. Wheeler	9.48	1728.1	283	113	75	.601	283	3.28	1,820	5	3	0	1,475	630	683	166	490	76	0	14	7,086	41	2.55	3.71	0.86	25.7	6.9	1.14	.289	3.56	82	3.28	80	7.68	164.6
12	Corey Kluber C. Kluber	9.46	1641.2	271	116	77	.601	260	3.44	1,725	18	8	1	1,486	627	684	177	368	65	4	9	6,688	31	2.02	4.69	0.97	25.8	5.5	1.13	.301	3.75	83	3.22	78	8.15	161.7
13	Tim Lincecum T. Lincecum	9.29	1682.0	278	110	89	.553	270	3.74	1,736	10	7	1	1,506	699	746	147	669	44	3	33	7,120	107	3.58	2.59	0.79	24.4	9.4	1.29	.300	3.99	99	3.44	90	8.06	81.5
14	Sandy Koufax S. Koufax	9.28	2324.1	397	165	87	.655	314	2.76	2,396	137	40	9	1,754	713	806	204	817	18	44	48	9,497	87	3.16	2.93	0.79	25.2	8.6	1.11	.256	3.12	75	2.69	75	6.79	226.6
15	Kevin Gausman K. Gausman	9.20	1911.0	361	112	113	.498	322	3.81	1,954	4	2	0	1,835	810	866	233	535	38	11	11	7,986	64	2.52	3.65	1.10	24.5	6.7	1.24	.307	4.08	92	3.59	85	8.64	132.7
16	Carlos Carrasco C. Carrasco	9.05	1687.1	335	112	105	.516	286	4.22	1,696	11	4	2	1,673	792	832	221	468	56	23	21	7,073	61	2.50	3.62	1.18	24.0	6.6	1.27	.313	4.44	102	3.76	90	8.92	74.1
17	Lance Lynn L. Lynn	9.04	2006.1	364	143	99	.591	340	3.74	2,015	4	2	1	1,856	834	916	231	704	89	4	21	8,520	61	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
18	Sonny Gray S. Gray	9.03	1918.0	339	125	102	.551	330	3.58	1,925	7	5	0	1,675	763	836	192	621	57	2	5	7,952	106	2.91	3.10	0.90	24.2	7.8	1.20	.288	3.92	87	3.51	85	7.86	136.2
19	Francisco Liriano F. Liriano	9.01	1813.2	419	112	114	.496	300	4.15	1,815	3	1	1	1,649	837	911	184	816	62	19	15	7,781	100	4.05	2.22	0.91	23.3	10.5	1.36	.299	4.52	101	3.88	95	8.18	39.3
20	Justin Verlander J. Verlander	8.96	3567.2	555	266	158	.627	555	3.32	3,553	26	9	0	3,046	1,317	1,428	371	1,004	121	0	28	14,607	99	2.53	3.54	0.94	24.3	6.9	1.14	.280	3.60	79	3.43	81	7.68	310.9
21	Sam McDowell S. McDowell	8.86	2492.1	425	141	134	.513	346	3.17	2,453	103	23	14	1,948	879	999	164	1,312	59	39	74	10,587	140	4.74	1.87	0.59	23.2	12.4	1.31	.270	3.61	90	3.06	84	7.03	160.4
22	Johan Santana J. Santana	8.83	2025.2	360	139	78	.641	284	3.20	1,988	15	10	1	1,726	721	773	220	567	36	23	13	8,262	68	2.52	3.51	0.98	24.1	6.9	1.13	.276	3.43	74	3.43	81	7.67	187.6
23	Hideo Nomo H. Nomo	8.73	1976.1	323	123	109	.530	318	4.24	1,918	16	9	0	1,768	932	993	251	908	38	2	31	8,462	109	4.13	2.11	1.14	22.7	10.7	1.35	.284	4.52	102	4.22	98	8.05	14.5
24	David Price D. Price	8.72	2143.2	400	157	82	.657	322	3.32	2,076	17	3	3	1,930	790	865	221	562	63	19	16	8,807	40	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
25	Charlie Morton C. Morton	8.72	2267.2	416	147	134	.523	409	4.13	2,196	3	2	0	2,143	1,040	1,139	226	859	200	1	27	9,755	72	3.41	2.56	0.90	22.5	8.8	1.32	.306	4.52	103	3.89	97	8.51	36.6