Between the 2000 and 2009 seasons, Andrew Bailey had the best ERA, with an ERA of 1.84.

Interpreted as:

lowest career era with a minimum of 0.5 IP per team game by a player in the 2000's

	NAME	ERA	G	W	L	W%	GS	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Andrew Bailey A. Bailey	1.84	68	6	3	.667	0	91	0	0	26	83.1	49	17	17	5	24	0	54	3	323	6	9.83	2.59	3.79	0.54	28.2	7.4	0.88	.217	1.84	43	2.55	59	5.29	16.7
2	Tommy Hanson T. Hanson	2.89	21	11	4	.733	21	116	0	0	0	127.2	105	41	42	10	46	5	0	1	522	2	8.18	3.24	2.52	0.70	22.2	8.8	1.18	.275	2.96	70	3.49	82	7.40	10.5
3	Tim Lincecum T. Lincecum	2.90	90	40	17	.702	89	676	6	3	0	598.2	472	193	211	33	217	14	0	8	2,451	38	10.16	3.26	3.12	0.50	27.6	8.9	1.15	.291	3.17	68	2.75	65	7.10	99.7
4	Randy Wells R. Wells	2.95	31	12	10	.545	27	105	0	0	0	170.2	165	56	67	14	49	6	2	4	712	3	5.54	2.58	2.14	0.74	14.7	6.9	1.25	.281	3.53	68	3.89	91	8.70	7.3
5	Pedro Martinez P. Martinez	3.01	227	112	50	.691	227	1,620	18	6	0	1468.0	1,171	491	530	132	350	86	0	10	5,917	24	9.93	2.15	4.63	0.81	27.4	5.9	1.04	.279	3.25	68	2.91	67	7.18	241.6
6	Johan Santana J. Santana	3.12	310	122	60	.670	234	1,733	9	6	1	1709.2	1,430	592	641	187	473	34	23	10	6,946	65	9.12	2.49	3.66	0.98	24.9	6.8	1.11	.275	3.37	70	3.37	78	7.53	181.5
7	Adam Wainwright A. Wainwright	3.17	149	46	24	.657	86	511	3	0	3	644.0	616	227	248	49	193	19	11	8	2,714	19	7.14	2.70	2.65	0.68	18.8	7.1	1.26	.292	3.47	76	3.53	83	8.61	52.5
8	Jair Jurrjens J. Jurrjens	3.21	72	30	21	.588	72	304	0	0	0	434.0	398	155	174	30	156	8	0	10	1,819	8	6.30	3.24	1.95	0.62	16.7	8.6	1.28	.279	3.61	76	3.74	88	8.25	25.2
9	Roy Oswalt R. Oswalt	3.23	283	137	70	.662	271	1,473	18	6	0	1803.1	1,756	647	695	154	412	66	5	30	7,455	21	7.35	2.06	3.58	0.77	19.8	5.5	1.20	.299	3.47	75	3.34	76	8.76	208.1
10	Jake Peavy J. Peavy	3.26	215	95	68	.583	215	1,366	7	3	0	1362.2	1,169	494	525	136	441	45	0	31	5,626	26	9.02	2.91	3.10	0.90	24.3	7.8	1.18	.284	3.47	82	3.45	82	7.72	115.8
11	Brandon Webb B. Webb	3.27	199	87	62	.584	198	1,065	15	8	0	1319.2	1,200	479	557	92	435	50	1	34	5,515	56	7.26	2.97	2.45	0.63	19.3	7.9	1.24	.286	3.80	72	3.49	78	8.18	146.6
12	John Smoltz J. Smoltz	3.28	367	56	42	.571	125	986	6	2	154	1058.2	982	386	405	93	236	19	204	29	4,324	26	8.38	2.01	4.18	0.79	22.8	5.5	1.15	.297	3.44	76	3.09	71	8.35	147.5
13	Kevin Brown K. Brown	3.30	137	54	36	.600	129	696	6	1	0	825.2	766	303	342	68	218	31	0	7	3,417	26	7.59	2.38	3.19	0.74	20.4	6.4	1.19	.290	3.73	78	3.34	76	8.35	99.9
14	Roger Clemens R. Clemens	3.34	229	107	50	.682	228	1,356	3	1	0	1454.1	1,268	539	596	129	478	45	0	19	6,029	53	8.39	2.96	2.84	0.80	22.5	7.9	1.20	.283	3.69	75	3.42	76	7.85	169.1
15	Randy Johnson R. Johnson	3.34	287	143	78	.647	281	2,182	32	12	0	1885.1	1,616	699	790	212	484	89	3	22	7,686	34	10.42	2.31	4.51	1.01	28.4	6.3	1.11	.298	3.77	75	3.12	70	7.71	275.2
16	Clayton Kershaw C. Kershaw	3.36	53	13	13	.500	51	285	0	0	0	278.2	228	104	106	18	143	2	1	7	1,171	18	9.20	4.62	1.99	0.58	24.3	12.2	1.33	.290	3.42	81	3.46	82	7.36	23.1
17	Rich Harden R. Harden	3.39	135	50	29	.633	127	783	2	1	0	753.2	603	284	311	70	329	16	2	15	3,136	26	9.35	3.93	2.38	0.84	25.0	10.5	1.24	.275	3.71	77	3.57	81	7.20	68.5
18	Roy Halladay R. Halladay	3.40	275	139	69	.668	267	1,400	47	14	0	1883.1	1,832	712	790	151	374	52	4	21	7,712	37	6.69	1.79	3.74	0.72	18.2	4.8	1.17	.293	3.78	74	3.31	74	8.75	243.9
19	Josh Johnson J. Johnson	3.40	86	34	16	.680	76	425	3	0	0	481.1	448	182	198	36	175	12	1	16	2,016	18	7.95	3.27	2.43	0.67	21.1	8.7	1.29	.301	3.70	79	3.49	81	8.38	42.5
20	Brad Bergesen B. Bergesen	3.43	19	7	5	.583	19	65	1	0	0	123.1	126	47	52	11	32	5	0	4	519	2	4.74	2.34	2.03	0.80	12.5	6.2	1.28	.283	3.79	76	4.09	89	9.19	6.7
21	Felix Hernandez F. Hernandez	3.45	138	58	41	.586	138	810	7	3	0	905.0	863	347	385	80	287	27	0	13	3,786	46	8.06	2.85	2.82	0.80	21.4	7.6	1.27	.303	3.83	80	3.53	82	8.58	80.6
22	Tim Hudson T. Hudson	3.50	290	137	76	.643	289	1,270	21	11	0	1923.1	1,837	749	818	156	570	71	0	59	8,024	52	5.94	2.67	2.23	0.73	15.8	7.1	1.25	.282	3.83	79	3.81	86	8.60	135.6
23	Mark Prior M. Prior	3.51	106	42	29	.592	106	757	5	1	0	657.0	582	256	277	77	223	31	0	10	2,771	21	10.37	3.05	3.39	1.05	27.3	8.0	1.23	.300	3.79	81	3.40	78	7.97	70.6
24	Carlos Zambrano C. Zambrano	3.51	259	105	68	.607	238	1,324	9	4	0	1551.1	1,313	605	669	126	698	81	4	36	6,593	49	7.68	4.05	1.90	0.73	20.1	10.6	1.30	.272	3.88	80	3.94	89	7.62	82.3
25	Matt Cain M. Cain	3.53	138	44	51	.463	137	729	8	2	0	872.1	744	342	357	77	349	21	1	20	3,650	38	7.52	3.60	2.09	0.79	20.0	9.6	1.25	.270	3.68	81	3.88	91	7.68	37.8