The Seattle Mariners have a run differential of 173 runs in the regular-season and playoffs since 2020.
| TEAM | DIFF | SEASON | G | W% | W | L | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Mariners | -49 | 2020 | 60 | .450 | 27 | 33 | 1,929 | 254 | 435 | 88 | 5 | 60 | 244 | 207 | 30 | 545 | 50 | 16 | 2,181 | 713 | 153 | 3 | 12 | 5 | 35 | .226 | .309 | .370 | .678 |
| 2 | | Mariners | -51 | 2021 | 162 | .556 | 90 | 72 | 5,355 | 697 | 1,209 | 233 | 11 | 199 | 673 | 535 | 72 | 1,492 | 64 | 24 | 6,007 | 2,061 | 443 | 9 | 36 | 8 | 92 | .226 | .303 | .385 | .688 |
| 3 | | Mariners | 68 | 2022 | 167 | .551 | 92 | 75 | 5,577 | 713 | 1,281 | 243 | 20 | 201 | 685 | 613 | 92 | 1,456 | 84 | 28 | 6,337 | 2,167 | 464 | 9 | 46 | 19 | 122 | .230 | .314 | .389 | .702 |
| 4 | | Mariners | 99 | 2023 | 162 | .543 | 88 | 74 | 5,500 | 758 | 1,333 | 282 | 12 | 210 | 728 | 548 | 111 | 1,603 | 118 | 30 | 6,200 | 2,269 | 504 | 4 | 37 | 14 | 95 | .242 | .321 | .413 | .734 |
| 5 | | Mariners | 69 | 2024 | 162 | .525 | 85 | 77 | 5,330 | 676 | 1,195 | 228 | 13 | 185 | 642 | 571 | 116 | 1,625 | 140 | 28 | 6,065 | 2,004 | 426 | 14 | 34 | 13 | 106 | .224 | .311 | .376 | .687 |
| 6 | | Mariners | 37 | 2025 | 119 | .555 | 66 | 53 | 4,054 | 547 | 987 | 156 | 6 | 171 | 524 | 408 | 64 | 1,062 | 125 | 28 | 4,573 | 1,668 | 333 | 21 | 26 | 19 | 74 | .243 | .321 | .411 | .732 |
| Total | 173 | 832 | .538 | 448 | 384 | 27,745 | 3,645 | 6,440 | 1,230 | 67 | 1,026 | 3,496 | 2,882 | 485 | 7,783 | 581 | 154 | 31,363 | 10,882 | 2,323 | 60 | 191 | 78 | 524 | .232 | .313 | .392 | .706 |
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