Lucas Gilbreath had the highest strikeout percentage this season, with a strikeout percentage of 50.0.

Interpreted as:

MLB pitcher highest strikeout% this regular season

	NAME	K%	SEASON	TM	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Lucas Gilbreath L. Gilbreath	50.0	2025	COL	1	0	0		0	9.00	2	0	0	0	1.0	1	1	1	1	0	0	1	0	4	0	18.00	0.00		9.00	0.0	1.00	.000	9.00	189	12.13	280	9.00	-0.8
2	Jose Espada J. Espada	44.4	2025	BAL	1	0	0		0	0.00	4	0	0	0	3.0	1	0	0	0	0	0	1	0	9	0	12.00	0.00		0.00	0.0	0.33	.200	0.00	0	0.46	11	3.00	1.2
3	Mason Miller M. Miller	44.4	2025	TOT	60	1	2	.333	0	2.63	104	0	0	22	61.2	28	18	19	5	28	1	37	2	234	3	15.18	4.09	3.71	0.73	12.0	0.91	.240	2.77	64	2.22	53	4.09	13.2
4	Cole Ragans C. Ragans	38.1	2025	KCR	13	3	3	.500	13	4.67	98	0	0	0	61.2	53	32	33	7	20	2	0	0	257	3	14.30	2.92	4.90	1.02	7.8	1.18	.354	4.82	109	2.50	60	7.74	11.5
5	Edwin Díaz E. Díaz	38.0	2025	NYM	62	6	3	.667	0	1.63	98	0	0	28	66.1	37	12	14	4	21	8	48	0	258	7	13.30	2.85	4.67	0.54	8.1	0.87	.260	1.90	40	2.27	55	5.02	13.5
6	Ryan Burr R. Burr	37.5	2025	TOR	2	1	0	1.000	0	0.00	3	0	0	0	2.0	1	0	0	0	1	0	0	0	8	0	13.50	4.50	3.00	0.00	12.5	1.00	.250	0.00	0	1.63	39	4.50	0.6
7	José Quijada J. Quijada	37.5	2025	LAA	2	0	0		0	0.00	3	0	0	0	1.1	1	0	0	0	2	0	0	0	8	0	20.25	13.50	1.50	0.00	25.0	2.25	.333	0.00	0	3.13	73	6.75	0.2
8	Kyle Bradish K. Bradish	37.3	2025	BAL	6	1	1	.500	6	2.53	47	0	0	0	32.0	23	9	9	3	10	1	0	0	126	0	13.22	2.81	4.70	0.84	7.9	1.03	.308	2.53	63	2.44	60	6.47	5.9
9	Aroldis Chapman A. Chapman	37.3	2025	BOS	67	5	3	.625	0	1.17	85	0	0	32	61.1	28	8	9	3	15	0	43	0	228	6	12.47	2.20	5.67	0.44	6.6	0.70	.200	1.32	27	1.73	41	4.11	16.8
10	Josh Hader J. Hader	36.9	2025	HOU	48	6	2	.750	0	2.05	76	0	0	28	52.2	29	12	16	8	16	2	41	1	206	2	12.99	2.73	4.75	1.37	7.8	0.85	.202	2.73	51	3.24	79	4.96	5.2
11	Connelly Early C. Early	36.7	2025	BOS	4	1	2	.333	4	2.33	29	0	0	0	19.1	17	5	6	0	4	1	0	0	79	0	13.50	1.86	7.25	0.00	5.1	1.09	.378	2.79	54	0.90	21	7.91	7
12	Fernando Cruz F. Cruz	36.0	2025	NYY	49	3	4	.429	0	3.56	72	0	0	2	48.0	33	19	21	5	24	3	4	0	200	5	13.50	4.50	3.00	0.94	12.0	1.19	.292	3.94	87	3.17	74	6.19	5.9
13	Freddy Tarnok F. Tarnok	35.7	2025	MIA	5	1	0	1.000	0	2.45	10	0	0	1	7.1	1	2	2	1	4	1	3	0	28	0	12.27	4.91	2.50	1.23	14.3	0.68	.000	2.45	57	4.22	102	1.23	-0.1
14	Ty Adcock T. Adcock	35.7	2025	NYM	3	0	0		0	3.00	5	0	0	0	3.0	2	1	1	1	2	0	1	0	14	0	15.00	6.00	2.50	3.00	14.3	1.33	.167	3.00	74	6.13	150	6.00	-0.7
15	Chase Burns C. Burns	35.6	2025	CIN	13	0	3	.000	8	4.57	67	0	0	0	43.1	41	22	25	5	16	0	1	0	188	0	13.92	3.32	4.19	1.04	8.5	1.32	.360	5.19	102	2.64	60	8.52	8
16	Jeremiah Estrada J. Estrada	35.5	2025	SDP	77	4	5	.444	0	3.45	108	0	0	3	73.0	58	28	31	12	27	3	7	2	304	3	13.32	3.33	4.00	1.48	8.9	1.16	.299	3.82	85	3.54	87	7.15	4.5
17	Bryan Abreu B. Abreu	35.5	2025	HOU	70	3	4	.429	0	2.28	105	0	0	7	71.0	51	18	18	4	31	4	19	0	296	4	13.31	3.93	3.39	0.51	10.5	1.15	.309	2.28	56	2.38	58	6.46	13.9
18	Félix Bautista F. Bautista	35.2	2025	BAL	35	1	1	.500	0	2.60	50	0	0	19	34.2	16	10	10	3	23	0	28	0	142	1	12.98	5.97	2.17	0.78	16.2	1.13	.197	2.60	65	3.36	82	4.15	2.8
19	Danny Young D. Young	35.1	2025	NYM	10	0	0		0	4.32	13	0	0	0	8.1	9	4	5	0	3	1	4	0	37	0	14.04	3.24	4.33	0.00	8.1	1.44	.450	5.40	107	1.45	35	9.72	2.5
20	Griffin Jax G. Jax	35.0	2025	TOT	73	1	7	.125	2	4.23	99	0	0	0	66.0	64	31	33	7	21	1	6	3	283	0	13.50	2.86	4.71	0.95	7.4	1.29	.368	4.50	105	2.51	61	8.73	11.9
21	Devin Williams D. Williams	34.7	2025	NYY	67	4	6	.400	0	4.79	90	0	0	18	62.0	45	33	37	5	25	4	29	1	259	4	13.06	3.63	3.60	0.73	9.7	1.13	.296	5.37	117	2.68	62	6.53	10.9
22	Erik Sabrowski E. Sabrowski	34.7	2025	CLE	33	0	1	.000	0	1.84	42	0	0	0	29.1	14	6	8	2	21	3	3	0	121	0	12.89	6.44	2.00	0.61	17.4	1.19	.226	2.45	45	3.61	87	4.30	1.7
23	Craig Kimbrel C. Kimbrel	34.7	2025	TOT	14	0	1	.000	0	2.25	17	0	0	0	12.0	10	3	4	2	7	0	5	0	49	0	12.75	5.25	2.43	1.50	14.3	1.42	.348	3.00	56	4.21	102	7.50	-0.1
24	Cade Smith C. Smith	34.7	2025	CLE	76	8	5	.615	0	2.93	104	0	0	16	73.2	55	24	31	4	19	4	30	3	300	3	12.71	2.32	5.47	0.49	6.3	1.00	.302	3.79	72	1.95	47	6.72	18
25	Grant Taylor G. Taylor	34.4	2025	CWS	36	2	4	.333	2	4.91	54	0	0	6	36.2	37	20	20	0	15	0	10	1	157	5	13.25	3.68	3.60	0.00	9.6	1.42	.420	4.91	119	1.41	33	9.08	11.5