most 250+ strikeout seasons by a starting pitcher

Nolan Ryan played the most seasons by a starting pitcher with 250+ strikeouts, with 27 seasons.

	NAME	SEAS	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	27	5,654	773	318	291	.522	773	3.18	222	61	0	5326.0	3,880	1,884	2,151	314	2,748	156	0	75	22,310	275	9.55	4.64	2.06	0.53	25.3	12.3	1.24	.265	3.63	6.56
2	Tommy John T. John	26	2,191	700	284	228	.555	700	3.35	162	46	0	4622.1	4,699	1,718	1,981	295	1,223	98	0	99	19,321	178	4.27	2.38	1.79	0.57	11.3	6.3	1.28	.284	3.86	9.15
3	Jamie Moyer J. Moyer	25	2,353	638	262	206	.560	638	4.27	33	10	0	3947.1	4,107	1,872	2,020	509	1,104	142	0	64	16,812	52	5.36	2.52	2.13	1.16	14.0	6.6	1.32	.283	4.61	9.36
4	Roger Clemens R. Clemens	24	4,671	707	354	184	.658	707	3.12	118	46	0	4913.2	4,182	1,706	1,884	363	1,579	159	0	63	20,227	143	8.56	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	7.66
5	Steve Carlton S. Carlton	24	4,104	709	327	240	.577	709	3.20	254	55	0	5165.1	4,616	1,835	2,096	405	1,814	53	0	145	21,457	177	7.15	3.16	2.26	0.71	19.1	8.5	1.24	.279	3.65	8.04
6	Jim Kaat J. Kaat	24	2,294	625	260	217	.545	625	3.43	180	31	0	4137.2	4,203	1,579	1,850	366	955	115	0	77	17,336	116	4.99	2.08	2.40	0.80	13.2	5.5	1.25	.282	4.02	9.14
7	Greg Maddux G. Maddux	23	3,366	740	355	226	.611	740	3.15	109	35	0	5001.0	4,717	1,750	1,974	351	996	137	0	177	20,388	70	6.06	1.79	3.38	0.63	16.5	4.9	1.14	.281	3.55	8.49
8	Dennis Martinez D. Martinez	23	1,984	562	230	182	.558	562	3.66	122	30	0	3730.2	3,631	1,517	1,701	349	1,067	113	0	60	15,613	70	4.79	2.57	1.86	0.84	12.7	6.8	1.26	.271	4.10	8.76
9	Don Sutton D. Sutton	23	3,545	756	321	253	.559	756	3.27	178	58	0	5248.1	4,670	1,905	2,095	469	1,333	81	0	96	21,500	110	6.08	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.59	8.01
10	Early Wynn E. Wynn	23	2,255	611	287	232	.553	611	3.56	289	49	0	4398.2	4,135	1,742	1,981	330	1,713	62	0	32	18,704	50	4.61	3.50	1.32	0.68	12.1	9.2	1.33	.265	4.05	8.46
11	Randy Johnson R. Johnson	22	4,818	603	301	166	.645	603	3.30	100	37	0	4103.0	3,320	1,504	1,692	408	1,491	188	0	37	16,937	109	10.57	3.27	3.23	0.89	28.4	8.8	1.17	.290	3.71	7.28
12	Tom Glavine T. Glavine	22	2,607	682	305	203	.600	682	3.54	56	25	0	4413.1	4,298	1,734	1,900	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	8.76
13	Bert Blyleven B. Blyleven	22	3,694	685	286	248	.536	685	3.31	242	60	0	4957.1	4,614	1,823	2,021	428	1,316	155	0	67	20,429	114	6.71	2.39	2.81	0.78	18.1	6.4	1.20	.282	3.67	8.38
14	Jerry Reuss J. Reuss	22	1,830	547	212	185	.534	547	3.64	127	39	0	3539.2	3,612	1,430	1,638	239	1,068	57	0	101	15,009	103	4.65	2.72	1.71	0.61	12.2	7.1	1.32	.285	4.16	9.18
15	Phil Niekro P. Niekro	22	3,181	716	302	262	.535	716	3.37	245	45	0	5149.2	4,815	1,928	2,227	465	1,703	116	0	73	21,585	207	5.56	2.98	1.87	0.81	14.7	7.9	1.27	.270	3.89	8.42
16	Gaylord Perry G. Perry	22	3,372	690	305	252	.548	690	3.10	303	53	0	5156.2	4,762	1,778	2,045	382	1,314	101	0	144	21,140	150	5.89	2.29	2.57	0.67	16.0	6.2	1.18	.274	3.57	8.31
17	Red Ruffing R. Ruffing	22	1,869	538	264	212	.555	538	3.82	335	45	0	4132.2	4,094	1,755	2,016	249	1,463	51	0		17,623	44	4.07	3.19	1.28	0.54	10.6	8.3	1.34	.275	4.39	8.92
18	Herb Pennock H. Pennock	22	1,035	419	217	145	.599	419	3.59	249	35	0	3137.2	3,488		1,477	117	749	28	0		13,351	51	2.97	2.15	1.38	0.34	7.8	5.6	1.35	.295	4.24	10.00
19	Bartolo Colon B. Colon	21	2,502	552	246	187	.568	552	4.12	38	13	0	3434.0	3,565	1,571	1,705	436	944	63	0	47	14,541	45	6.56	2.47	2.65	1.14	17.2	6.5	1.31	.295	4.47	9.34
20	Mike Morgan M. Morgan	21	1,246	411	127	178	.416	411	4.30	46	10	0	2482.2	2,661	1,186	1,308	242	828	67	0	64	10,648	92	4.52	3.00	1.50	0.88	11.7	7.8	1.41	.293	4.74	9.65
21	Frank Tanana F. Tanana	21	2,734	616	236	236	.500	616	3.67	143	34	0	4136.1	4,019	1,688	1,893	445	1,227	128	0	110	17,413	114	5.95	2.67	2.23	0.97	15.7	7.0	1.27	.278	4.12	8.74
22	Joe Niekro J. Niekro	21	1,541	500	201	186	.519	500	3.65	107	29	0	3216.1	3,144	1,306	1,485	252	1,123	58	0	56	13,637	156	4.31	3.14	1.37	0.71	11.3	8.2	1.33	.271	4.16	8.80
23	Warren Spahn W. Spahn	21	2,501	665	358	227	.612	665	3.08	382	63	0	5101.0	4,703	1,743	1,951	422	1,383	39	0	52	20,960	74	4.41	2.44	1.81	0.74	11.9	6.6	1.19	.258	3.44	8.30
24	Ted Lyons T. Lyons	21	1,010	484	245	210	.538	484	3.60	356	27	0	3907.0	4,196	1,564	1,900	208	1,027	30	0		16,676	48	2.33	2.37	0.98	0.48	6.1	6.2	1.34	.277	4.38	9.67
25	Eppa Rixey E. Rixey	21	1,244	554	247	239	.508	554	3.15	289	37	0	4171.2	4,335	1,462	1,849	84	982	71	0		17,427	84	2.68	2.12	1.27	0.18	7.1	5.6	1.27	.283	3.99	9.35