Giancarlo Stanton has the most games with 4+ strikeouts, with 31 games.

Interpreted as:

most 4+ strikeouts regular-season games by a player

	NAME	G	SO	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Giancarlo Stanton G. Stanton	31	126	145	3	8	4	0	1	3	2	0	0	0	147	15	5	0	0	0	2	.055	.068	.103	.171
2	Ryan Howard R. Howard	27	109	131	10	12	3	0	5	13	8	0	0	0	140	30	8	0	1	1	0	.092	.143	.229	.372
3	Chris Davis C. Davis	26	106	120	1	1	0	0	0	1	3	0	0	0	124	1	0	0	1	0	2	.008	.032	.008	.041
4	Eugenio Suárez E. Suárez	25	101	111	1	4	1	1	0	2	5	1	0	0	117	7	2	0	0	0	0	.036	.085	.063	.149
5	Joey Gallo J. Gallo	25	100	106	1	2	0	1	0	4	3	0	0	0	109	4	1	0	0	0	0	.019	.046	.038	.084
6	Reggie Jackson R. Jackson	23	93	118	6	9	2	0	2	9	5	0	0	0	123	17	4	0	0	0	0	.076	.114	.144	.258
7	Jim Thome J. Thome	20	82	101	5	8	1	0	2	12	2	0	0	0	104	15	3	0	1	0	2	.079	.096	.149	.245
8	Adam Dunn A. Dunn	19	77	81	1	2	0	0	1	3	3	0	0	0	84	5	1	0	0	0	0	.025	.060	.062	.121
9	Bo Jackson B. Jackson	19	77	83	1	2	1	0	0	0	0	0	0	0	83	3	1	0	0	0	1	.024	.024	.036	.060
10	Miguel Sanó M. Sanó	18	73	87	5	6	0	0	3	4	2	0	0	0	89	15	3	0	0	0	0	.069	.090	.172	.262
11	Mark Reynolds M. Reynolds	18	72	86	6	7	1	0	3	9	2	0	2	0	88	17	4	0	0	0	0	.081	.102	.198	.300
12	Sammy Sosa S. Sosa	17	72	82	3	5	1	0	1	3	1	0	0	0	83	9	2	0	0	0	1	.061	.072	.110	.182
13	Rob Deer R. Deer	17	69	75	2	3	0	0	2	5	4	0	1	0	79	9	2	0	0	0	0	.040	.089	.120	.209
14	Trevor Story T. Story	16	65	73	4	4	0	0	3	9	2	1	1	0	77	13	3	0	1	0	0	.055	.091	.178	.269
15	Javier Báez J. Báez	16	67	72	2	4	0	0	0	0	1	0	0	0	73	4	0	0	0	0	0	.056	.068	.056	.124
16	Jose Canseco J. Canseco	16	65	74	4	4	4	0	0	2	2	0	0	0	76	8	4	0	0	0	0	.054	.079	.108	.187
17	Ryan McMahon R. McMahon	15	62	66	1	4	2	0	1	2	1	0	0	0	67	9	3	0	0	0	0	.061	.075	.136	.211
18	Yoán Moncada Y. Moncada	15	61	71	2	5	2	0	0	0	2	0	0	1	73	7	2	0	0	0	0	.070	.096	.099	.194
19	Mike Napoli M. Napoli	15	60	73	2	2	0	0	0	1	2	0	0	0	75	2	0	0	0	0	2	.027	.053	.027	.081
20	Andres Galarraga A. Galarraga	15	60	66	0	3	0	0	0	0	0	0	0	0	66	3	0	0	0	0	0	.045	.045	.045	.091
21	Dave Kingman D. Kingman	15	61	67	3	4	1	0	2	3	1	0	0	0	68	11	3	0	0	0	0	.060	.074	.164	.238
22	Dick Allen D. Allen	15	62	67	2	2	1	0	1	2	0	0	0	0	67	6	2	0	0	0	0	.030	.030	.090	.119
23	Ian Happ I. Happ	14	56	66	3	6	1	0	1	9	2	1	1	0	70	10	2	0	1	0	1	.091	.129	.152	.280
24	Aaron Judge A. Judge	14	59	65	2	2	0	0	1	4	1	0	0	1	66	5	1	0	0	0	0	.031	.045	.077	.122
25	Kyle Schwarber K. Schwarber	14	56	58	2	1	0	0	0	0	3	0	0	0	61	1	0	0	0	0	0	.017	.066	.017	.083