Grover Alexander had the most games pitched when pitching at least 10 innings, with 57 games.

Interpreted as:

most regular-season games by a player with 10+ ip

	NAME	G	IP	W	L	W%	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Grover Alexander G. Alexander	57	644.0	38	15	.717	57	1.55	278	57	6	0	547		158	12	128	3	0		2,533	2	3.89	1.79	2.17	0.17	11.0	5.1	1.05	.253	2.21	7.64
2	Walter Johnson W. Johnson	55	641.1	31	21	.596	52	0.91	360	52	10	0	458		117	1	133	19	3		2,458	20	5.05	1.87	2.71	0.01	14.6	5.4	0.92	.235	1.64	6.43
3	Gaylord Perry G. Perry	37	406.1	13	9	.591	36	1.77	271	16	1	0	298	80	93	26	78	6	0	23	1,558	7	6.00	1.73	3.47	0.58	17.4	5.0	0.93	.231	2.06	6.60
4	Ted Lyons T. Lyons	35	391.2	19	15	.559	35	2.21	112	34	1	0	345	96	126	13	103	3	0		1,590	4	2.57	2.37	1.09	0.30	7.0	6.5	1.14	.244	2.90	7.93
5	Eppa Rixey E. Rixey	33	384.0	19	14	.576	33	1.73	135	32	0	0	335	74	102	5	106	8	0		1,541	11	3.16	2.48	1.27	0.12	8.8	6.9	1.15	.256	2.39	7.85
6	Red Faber R. Faber	32	356.2	23	7	.767	30	1.92	148	28	1	0	297	76	88	8	64	12	2		1,399	6	3.73	1.61	2.31	0.20	10.6	4.6	1.01	.248	2.22	7.49
7	Wilbur Cooper W. Cooper	32	361.2	20	8	.714	32	1.72	130	32	1	0	287	69	83	8	86	9	0		1,422	5	3.24	2.14	1.51	0.20	9.1	6.0	1.03	.235	2.07	7.14
8	Bucky Walters B. Walters	28	304.0	19	7	.731	28	1.69	98	25	2	0	239	57	67	14	100	2	0		1,214	2	2.90	2.96	0.98	0.41	8.1	8.2	1.12	.225	1.98	7.08
9	Earl Whitehill E. Whitehill	25	276.0	11	11	.500	25	2.61	97	22	1	0	267	80	92	8	92	7	0		1,169	6	3.16	3.00	1.05	0.26	8.3	7.9	1.30	.268	3.00	8.71
10	Red Ruffing R. Ruffing	25	285.2	11	12	.478	25	2.65	151	22	2	0	234	84	96	14	100	1	0		1,174	0	4.76	3.15	1.51	0.44	12.9	8.5	1.17	.242	3.02	7.37
11	Stan Coveleski S. Coveleski	25	275.2	14	11	.560	25	1.37	72	24	3	0	212	42	51	3	69	2	0		1,089	3	2.35	2.25	1.04	0.10	6.6	6.3	1.02	.222	1.67	6.92
12	Hippo Vaughn H. Vaughn	25	278.1	12	10	.545	25	1.26	128	24	2	0	237		75	4	61	8	0		1,106	7	4.14	1.97	2.10	0.13	11.6	5.5	1.07	.257	2.43	7.66
13	Eddie Cicotte E. Cicotte	25	272.2	10	14	.417	25	1.16	110	25	2	0	209		66	5	64	4	0		1,062	5	3.63	2.11	1.72	0.17	10.4	6.0	1.00	.232	2.18	6.90
14	Lefty Grove L. Grove	24	286.2	14	8	.636	24	2.04	135	22	1	0	242	65	71	9	96	2	0		1,184	3	4.24	3.01	1.41	0.28	11.4	8.1	1.18	.247	2.23	7.60
15	Jeff Pfeffer J. Pfeffer	24	281.0	8	11	.421	24	1.51	99	22	2	0	221	47	69	3	60	9	0		1,100	3	3.17	1.92	1.65	0.10	9.0	5.5	1.00	.235	2.21	7.08
16	Robin Roberts R. Roberts	23	256.2	12	7	.632	23	2.07	109	17	1	0	207	59	60	17	59	0	0	8	1,005	2	3.82	2.07	1.85	0.60	10.8	5.9	1.04	.232	2.10	7.26
17	Warren Spahn W. Spahn	23	263.2	11	10	.524	23	1.71	120	20	0	0	189	50	57	14	64	0	0	5	1,018	2	4.10	2.18	1.88	0.48	11.8	6.3	0.96	.213	1.95	6.45
18	Carl Hubbell C. Hubbell	23	260.2	10	11	.476	22	1.66	122	20	3	0	189	48	56	16	47	0	1		1,009	4	4.21	1.62	2.60	0.55	12.1	4.7	0.91	.210	1.93	6.53
19	Dolf Luque D. Luque	23	254.0	11	9	.550	23	1.56	117	20	2	0	191	44	56	4	60	2	0		995	2	4.15	2.13	1.95	0.14	11.8	6.0	0.99	.230	1.98	6.77
20	Billy Pierce B. Pierce	21	234.0	8	10	.444	21	1.69	145	18	3	0	181	44	49	10	65	2	0	3	929	3	5.58	2.50	2.23	0.38	15.6	7.0	1.05	.242	1.88	6.96
21	Lon Warneke L. Warneke	21	219.1	10	9	.526	21	2.01	84	18	1	0	200	49	56	10	43	0	0		877	3	3.45	1.76	1.95	0.41	9.6	4.9	1.11	.257	2.30	8.21
22	Paul Derringer P. Derringer	21	234.0	8	11	.421	21	1.85	78	18	2	0	204	48	63	8	39	6	0		933	4	3.00	1.50	2.00	0.31	8.4	4.2	1.04	.244	2.42	7.85
23	Ed Walsh E. Walsh	21	258.2	10	9	.526	21	0.35	141	21	1	0	190		62	1	49	9	0		1,008	3	4.91	1.70	2.88	0.03	14.0	4.9	0.92	.234	2.16	6.61
24	Jim Palmer J. Palmer	20	213.1	5	5	.500	20	1.52	121	10	0	0	144	36	38	14	46	1	0	3	810	5	5.10	1.94	2.63	0.59	14.9	5.7	0.89	.207	1.60	6.08
25	Hal Newhouser H. Newhouser	20	219.0	16	4	.800	20	1.81	117	20	2	0	158	44	48	5	68	0	0		879	4	4.81	2.79	1.72	0.21	13.3	7.7	1.03	.222	1.97	6.49